Kodi 9-ME-BC ndi chiyani?

9-Me-BC (9-Methyl-β-carboline) yemwenso imadziwika kuti 9-MBC ndi buku la nootropic lochokera pagulu la β-carboline. The β-Carbolines amachokera ku banja loipa kwambiri la carboline. Izi zikutanthauza kuti amapangidwa mozungulira thupi la munthu komanso zipatso zina, nyama yophika, utsi wa fodya ndi khofi.

The β-Carbolines (BCs) amadziwika kuti ndi neurotoxic, komabe, posachedwapa zapezeka kuti 9-Me-Bc ndiyopindulitsa. 9-Ine-BC ndi dopaminergic neuroprotector yomwe imathandizanso kuzindikira ntchito.

9-Me-BC ufa komanso kapisozi wa 9-Me-BC kuwonjezera mawonekedwe ndi nootropic yabwino kwambiri. Popeza mosiyana ndi ma nootropics ena omwe maubwino awo amatha pambuyo pa maola ochepa, 9-Me-BC imapereka zotsatira zokhalitsa komanso zazitali.

9-ME-BC ufa- Zimagwira bwanji?

9-Me-BC ndiyabwino kwambiri nootropic yomwe imawonekera m'njira zingapo. Njira zingapo za 9-Me-BC zimathandizira kuti zizigwira bwino ntchito pochita.

Pansipa pali njira zogwirira ntchito za 9-Me-BC;

  1. Imakweza mulingo wa dopamine muubongo poletsa kuwonongeka kwa dopamine, mosiyana ndi zotsekemera zina monga caffeine yomwe imachepetsa dopamine chifukwa chamasulidwe ochulukirapo ndikugwiritsa ntchito.
  2. 9-Me-BC imalimbikitsa zochitika za dopamine, zimasiyanitsa komanso kuteteza ma neuron, dendrites ndi ma synapses muubongo. Ichi ndichifukwa chake imatha kupititsa patsogolo maphunziro, chikumbukiro ndi kuzindikira ntchito
  3. Zimakhudza tyrosine hydroxylase (TH) ndi zolemba zake mukamayenderana ndi tyrosine kinases. Ma tyrosine kinases amathandizira kutembenuza L-tyrosine kukhala L-Dopa woyang'anira kaphatikizidwe ka dopamine.
  4. 9-Me-BC imaletsa monoamine oxidase A ndi B (MAOA ndi MAOB) motero zimalepheretsa kupanga mankhwala a neurotoxic monga DOPAC kuchokera ku dopamine metabolism. Zinthu izi zimayambitsa kufa kwa ma dopaminergic neurons.
  5. 9-Me-BC imathandizira kupuma kwa mitochondrial. Zimakwaniritsa izi mwa kukulitsa kapena kuteteza NADH dehydrogenase, yomwe imagwiritsidwa ntchito potumiza zamagetsi popanga magetsi.
  6. 9-Me-BC ikhozanso kukulitsa ma neurotrophic factor monga Nerve grow factor (NGF), SHH (Sonic Hedgehog Signaling Molecule), Brain-derived neurotrophic factor (BDNF) yomwe imathandizira magwiridwe antchito amalingaliro, chidwi komanso chidwi.
  7. Zimalimbikitsa zochitika za neuronal komanso zimalimbikitsa kukula kwa ma neuron atsopano. Izi zimapangitsa kukumbukira ndi kuphunzira komanso magwiridwe antchito ambiri.
  8. Zotsutsa-zotupa. 9-me-BC imachitika ndikulimbana ndi kutupa kosatha muubongo pochepetsa ma cytokines otupa, omwe amadziwika kuti amayambitsa kudzikundikira kwama microglial komwe kumayambitsanso magwiridwe antchito.

Ubwino wa 9-ME-BC - Momwe 9-ME-BC Powder (Nootropic) ingakuthandizeni?

9-Ine-BC kuwonjezera ali ndi maubwino osiyanasiyana azaumoyo. Mapindu osiyanasiyana a 9-Me-BC ndi chifukwa cha zochitika zingapo zomwe zimawonetsa.

Pansipa pali zabwino za 9-Me-BC;

i. Zitha kupititsa patsogolo kuphunzira, kukumbukira komanso kuzindikira

9-Me-BC imathandizira ma neuron ndikuwonjezeranso kukula kwamaselo atsopano a neuron. Izi ndizofunikira kwambiri pakupititsa patsogolo maphunziro, chikumbukiro ndi magwiridwe antchito azidziwitso.

9-Me-BC nawonso kulimbikitsa ATP kupanga mphamvu mwa kupititsa patsogolo kupuma kwa mitochondrial. Chifukwa chake mphamvu zowonjezera zomwe zimalimbikitsa chidwi komanso kukhala tcheru.

Pakafukufuku wamakoswe, zowonjezera 9-Me-BC zoperekedwa masiku 10 zidapezeka kuti zikuwongolera kuphunzira. Kafukufukuyu adati izi zidachitika chifukwa cha kuchuluka kwa ma dopamine komanso kulimbikitsa kukula kwa ma synapses ndi ma dendrites.

9-Ine-BC

ii. Amathandizira kulimbana ndi kutupa

Kutupa ndimachitidwe achilengedwe momwe thupi limamenyera motsutsana ndi matenda kapena kuvulala. Komabe, kutupa kosatha kumatha kukhala kovulaza thupi ndipo kwakhala kukugwirizanitsidwa ndi matenda ambiri monga matenda ashuga ndi khansa.

Chifukwa chake zimakhala zofunikira kuti muchepetse kutupa uku kusanakhale koipa mthupi lanu. Mwamwayi, ufa wa 9-Me-BC ungathandize kupewa kutupa kosatha. Imalimbana ndi kutupa pochepetsa ma cytokines otupa.

iii. Ikhoza kupititsa patsogolo libido

9-Me-BC mankhwala a nootropic ndi dopaminergic kwambiri. Mankhwala a Dopaminergic amadziwika kuti amachulukitsa kuchuluka kwa dopamine muubongo. Izi zimapangitsa kuti ntchito ya dopamine igwirizane kwambiri ndi kuchuluka kwa libido.

iv. Itha kulimbikitsa magwiridwe antchito a othamanga

Kutha kwa 9-Me-BC kukulitsa kupanga mphamvu komanso kulimbikitsana komanso chidwi kumapangitsa kuti akhale woyenera kusintha magwiridwe antchito a othamanga.

Chidziwitso cha 9-Me-BC: Momwe mungagwiritsire ntchito 9-MBC?

Mlingo woyenera wa 9-Me-BC umatenga kapisozi umodzi wa 9-Me-BC tsiku lililonse. Kapisozi mmodzi wa 9-Me-BC ndi wofanana ndi 15 mg wa ufa wa 9-Me-BC.

Ndikofunika kutenga kapisozi wa 9-Me-BC m'mawa chifukwa zimadziwika kuti ziwonjezere kukhala tcheru, kusunthika, komanso chidwi, zomwe mungafunikire pochita masana.

Kodi ndizotetezeka komanso zovomerezeka kugwiritsa ntchito 9-MBC? Zowopsa za 9-me-bc?

9-MBC imadziwika kuti ndi yotetezeka chakudya chowonjezera. Kuchokera ku kafukufuku wa nyama, 9-Me-BC nootropic yoperekedwa kwamasiku 10 idapezeka kuti ndi yotetezeka kotheratu.

Komabe, palibe deta yomwe ikupezeka pankhani yogwiritsa ntchito 9-Me-BC yowonjezerapo kwa nthawi yayitali komanso mayesero ochepa azachipatala okhudzana ndi 9-Me-BC nootropic iyi.

Chifukwa chake ndikofunikira kuti muzisamala mukamamwa nootropic iyi popumira pakati kuti mupewe zovuta zilizonse za 9-Me-BC zomwe zingachitike.

Zowonjezera za 9-Me-BC ndizovomerezeka mdziko lililonse padziko lapansi. Amagawidwa m'magulu ndikugulitsidwa ngati chowonjezera cha zakudya motero chimayendetsedwa mofanana ndi zakudya za Food and Drug Administration.

Ndizovomerezeka kuti aliyense agule ndikugwiritsa ntchito zowonjezera za 9-Me-BC. Ngakhale, 9-Me-BC imawerengedwa kuti ndi yotetezedwa mwalamulo, amalangizidwa kuti munthu akafunsire kuchipatala asanachite izi.

Zotsatira za 9-Me-BC

Ngakhale zowonjezera 9-Me-BC nthawi zambiri zimawoneka ngati zotetezeka, pali zoyambitsa ziwiri zazikulu zomwe zingachitike ku 9-Me-Bc zomwe mungakumane nazo;

Chithunzi-tcheru - kuwonekera kwakanthawi kwa dzuwa kuyenera kupewedwa mukamagwiritsa ntchito Zowonjezera za 9-Me-BC chifukwa izi zitha kubweretsa kuwonongeka kwa DNA chifukwa cha kuwunikira kwa UV. Ngati mukuyenera kukhala pansi ndi kuwala kwa dzuwa kumafunika kuti mupewe zotsatirapo za 9-Me-BC.

Dopamine neurotoxicity ikhozanso kuchitika; komabe, izi zimachitika mukadutsa mulingo woyenera wa 9-Me-BC. Chifukwa chake, zitha kupewedwa potenga mulingo woyenera wa 9-Me-BC.

Zotsatira zina za 9-Me-BC zomwe zidanenedwa kuchokera kwa ogwiritsa ntchito omwe adagawana zomwe akumana nazo za 9-Me-BC zimaphatikizapo nseru komanso kupweteka mutu. Komabe, zovuta izi ndizosowa kwambiri ndipo zimangochitika munthu akamamwa mankhwala osokoneza bongo a 9-Me-BC.

Ndani angapindule ndi 9-me-bc (nootropic)?

Kwenikweni aliyense atha kupeza zabwino kuchokera ku 9-Me-BC nootropic. Komabe, magulu ena a anthu atha kupindula kwambiri ndi 9-Me-BC kuposa ena. Ogwira ntchito, ophunzira komanso othamanga atha kukolola zochuluka kuchokera Mapindu a 9-Me-BC.

Popeza, 9-Me-BC ndiyabwino kwambiri komanso ndi dopaminergic kwambiri, ndiwowonjezera wabwino kwa ophunzira omwe akufuna kuwonjezera chidwi, chidwi chophunzirira pomwe akupitilizabe kuphunzira ndi kukumbukira kukumbukira zambiri.

Kugwira ntchito kumatha kupanikiza komanso kutopetsa, koma mwamwayi 9-Me-BC imapereka chilimbikitso komanso mphamvu zomwe zimakupatsani mphamvu pantchito. Zimapangitsa ma neuron omwe amakupatsani chidwi nthawi zonse.

Ogwiritsa ntchito kuwunika kwa 9-Me-BC ali ndi chiyembekezo chotsimikizika popanda zovuta zina zomwe zanenedwa. Chifukwa chake zabwino kuwonjezera kwa onse.

9-Ine-BC

9-ME-BC ufa wogulitsa - Mungagule kuti 9-ME-BC?

9-Me-BC yogulitsa imapezeka mosavuta pa intaneti. Komabe, kuyera kwambiri kuyenera kutsimikiziridwa kuti mupeze zomwe mukuyembekezera. Ganizirani za kuwunika kwa 9-Me-BC kuchokera kwa ogwiritsa ntchito kuti mumvetsetse kapisozi wabwino kwambiri wa 9-Me-BC.

Monga zowonjezera zina, ndibwino kulingalira zoopsa za 9-Me-BC zomwe zitha kuchitika ndikutsatira njira zofunikira.

Ogwiritsa ntchito ambiri a 9-Me-BC amagula kuchokera kuvomerezedwa ogulitsa nootropics amene amapereka 9-Me-BC yogulitsa pamtengo wapamwamba kwambiri.

Mukamaganiza zogwiritsa ntchito 9-Me-BC mugule kuchokera kumakampani omwe amapereka 9-Me-BC kuti agulitsidwe mochuluka kuti musangalale ndi mitengo yotsika.

Zothandizira
  1. Gille G., Gruss M., Schmitt A., Braun K., Enzensperger C., Fleck C. ndi Appenroth D. (2011) 9-Methyl-b-carboline amalimbikitsa kuphunzira ndi kukumbukira makoswe. Neurodegen. Dis. 8, 195.
  2. Gruss, M., Appenroth, D., Flubacher, A., Enzenperger, C., Bock, J., Fleck, C.,… Braun, K. (2012). Kupititsa patsogolo chidziwitso cha 9-Methyl-β-carboline kumalumikizidwa ndi kuchuluka kwa hippocampal dopamine milingo ndi kuchuluka kwa dendritic ndi synaptic. Zolemba za Neurochemistry, 121 (6), 924-931.onetsani: 10.1111 / j.1471-4159.2012.07713. x.
  3. Hamann, J., Wernicke, C., Lehmann, J., Reichmann, H., Rommelspacher, H., & Gille, G. (2008). 9-Methyl-β-carboline imayang'anira mawonekedwe amitundu yosiyanasiyana ya dopaminergic neurones pachikhalidwe choyambirira cha mesencephalic. Neurochemistry Mayiko, 52 (4-5), 688-700.onetsani: 10.1016 / j.neuint.2007.08.018.
  4. Polanski W., Enzenperger C., Reichmann H. ndi Gille G. (2010) Makhalidwe apadera a 9-methyl-beta-carboline: kukondoweza, kuteteza ndi kusinthanso ma dopaminergic neurons kuphatikiza zotsutsana ndi zotupa. J. Neurochem. 113, 1659-1675.
  5. Wernicke, C., Hellmann, J., Ziêba, B., Kuter, K., Ossowska, K., Frenzel, M.,… Rommelspacher, H. (2010). 9-Methyl-b-carboline imakhala ndi zotsatira zobwezeretsa m'thupi la matenda a Parkinson. Malipoti Amankhwala, 19.
  6. RAW 9-METHYL-9H-BETA-CARBOLINE ufa (2521-07-5)

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