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Zinsinsi Zambiri za 7 Zokhudza Kugwiritsa Ntchito Ntchito, Mukudziwa
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Zinsinsi Zofunika za 7 Zokhudza Kugwiritsa Ntchito Ntchito, Mukudziwa?

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Chirichonse chokhudza Pramlintide

1. Yambitsaninso Pramlintide
2. Kodi pramlintide ndi yani?
3. Kodi pramlintide ikugwira ntchito bwanji pa inu?
4. Kodi ndichite chiyani kamodzi koyambitsa jekeseni?
5. Ndani Sagwiritse Ntchito Pramlintide?
6. Zochitika zosiyana kuchokera ku pramlintide
7. Kutsiliza

1. Yambitsaninso Pramlintide aasraw

Pramlintide (Symlin) ndi hormone yopangira yomwe imapezeka m'thupi la munthu mwachibadwa. Mankhwalawa amatha kuchepetsa shuga m'magazi ndipo, choncho, amagwiritsidwa ntchito makamaka ndi matenda a shuga 1 & 2 omwe ali ndi insulini. Kawirikawiri, Symlin hormone monga insulini imapangidwira pamatenda pamene shuga ndipamwamba. Mankhwalawa amagwira ntchito m'njira zosiyanasiyana kuti athetse magazi a shuga. Mutangotenga mlingo wanu, mankhwalawa amachepetsera mlingo umene chakudya chimachokera m'matumbo kuphatikizapo shuga - Kupititsa patsogolo shuga malonda pansi pa dzina lake Symlin ndipo sichipezeka ngati mankhwala ochiritsira.

Komabe, Pramlintide (196078-30-5) imatchinjiriza chiwindi chanu kuti musapange tizilombo toyambitsa matenda, zomwe zimapangitsa kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda, komanso tizilombo toyambitsa matenda. Kugwiritsa ntchito mankhwala kumachepetsa kuchepetsa chakudya chanu kuti chikhale choyenera ngakhale kwa anthu omwe akufuna kudula thupi lawo lowonjezera. M'maphunziro ambiri opangidwa ndi asayansi osiyanasiyana, Pramlintide yakhala yothandiza kuthandiza odwala kuchepetsa shuga lawo la magazi komanso kuthandiza ena kulamulira thupi lawo.

Pogwiritsira ntchito mankhwalawa, simukusowa kudandaula kuyambira pamene anavomerezedwa kuti anthu azidya ndi FDA mu March 2005. Komabe, musanagwiritse ntchito Pramlintide onetsetsani kuti mupite kukayezetsa mankhwala kuti mudziwe ngati mankhwalawa akuyenererani. Thupi laumunthu lingakhale lovuta makamaka momwe amachitira ndi mankhwala osiyanasiyana. Musangogula Pramlintide pa pepala ndipo muyambe kugwiritsa ntchito popanda dokotala wanu kudziwa. Kukhala mankhwala osakaniza, kumatanthauza kuti mukufunikira dokotala kuti awononge mlingo wake kapena akuphunzitseni momwe mungadzipangire.

Kuonjezerapo, pamene mukugula mankhwalawa mutsimikizire kuti muzilandira kuchokera kwa odalirika ndi odziwa bwino Pramlintide ogulitsa. Kugwiritsira ntchito mankhwala osokoneza bongo kungakhale koopsa, ndipo izi zingayambitse mavuto aakulu. Lankhulani ndi dokotala wanu kuti akuthandizeni kupeza Pramlintide yapamwamba kwambiri zotsatira. Mukawona zotsatira zoopsa zimathandizanso dokotala wanu nthawi yomweyo chisanafike.

Zinsinsi Zambiri za 7 Zokhudza Kugwiritsa Ntchito Ntchito, Mukudziwa

2. Kodi Pramlintide ndi ndani? aasraw

Monga tafotokozera pamwambapa, mankhwalawa ndi omwe amadalitsidwa ndi odwala matenda a shuga kuti awathandize kuchepetsa shuga m'magazi. Pramlintide yakhala yothandiza pochiza matenda a shuga kwa odwala omwe sakhala okwanira. Mankhwalawa angagwiritsidwe ntchito pamodzi ndi insulini kuti zikhale bwino. Komabe, onetsetsani kuti mwapeza mankhwala osokoneza bongo kuchokera kwa dokotala kuti musakhale ndi zotsatira zoyipa.

Kafukufuku wasonyeza kuti Pramlintide shuga imatha kuthandiza anthu amene akufuna kulamulira thupi lawo. Mankhwalawa amachepetsa chilakolako, ndipo pochita zimenezi, thupi limadya mafuta omwe alipo omwe amachititsa kulemera. Kugwiritsira ntchito mankhwalawa kungatanthauze kuti zidzakuthandizani kuti muyambe kudya, zomwe zimakhala njira yabwino kwambiri yowonera kulemera kwanu. Pramlintide imathandizanso kuchepetsa shuga chifukwa cha chiwindi. Komabe, mankhwalawa akuti amagwiritsa ntchito zambiri, koma mukhoza kutsimikizira ndi dokotala kapena asupe anu musanayambe kugwiritsa ntchito.

Pambuyo pa kafukufuku wamankhwala, adokotala akhozanso kukupatsani mankhwalawa kwa chifukwa china chilichonse chachipatala chomwe chingathetsedwe ndi Pramlintide. Nthawi zina mankhwalawa angagwiritsidwe ntchito ndi ena monga insulini kuti apindule bwino komanso kuthandiza wogwiritsa ntchito zotsatira zake. Onetsetsani kuti mumagwiritsa ntchito dokotala wanu muyezo wonse wa mankhwala a Pramlintide, kuti mupewe zotsatira zoopsa. Nthawi zina mungayambe kukumana ndi mavuto mwamsanga, mutenge mlingo wanu woyamba kapena ngakhale patapita kanthawi, ndipo mukusowa chithandizo chamankhwala mukangoyamba kukhala ndi vuto lililonse.

3. Kodi Pramlintide ikugwira ntchito bwanji? aasraw

Mankhwalawa ndi mawonekedwe a amylin hormone omwe amapangidwa m'thupi lanu ndi makoswe monga insulini. Symlin imagwiritsidwa ntchito popanga mankhwalawa monga chinthu chofunika kwambiri cha Pramlintide. Ndilo buku lopangidwa ndi anthu la amylin, ndi jekeseni, Pramlintide imagwira ntchito zitatu kuti zithandize kuchepa thupi ndi kuchepetsa chilakolako chanu. Kwa chikhalidwe, chimagwira ntchito kudzera mu ubongo. Apa ndi pamene zimakupangitsani kuti mumve bwino. Kudya ndi kugwirizana kwa ubongo. Mumakonda kudya chifukwa malingaliro anu amakuuzani kuti muli ndi njala. Ndi mankhwalawa, ubongo wanu umakuuzani kuti muli odzaza nthawi ya chakudya chomwe chimakupangitsani kudya pang'ono kapena kudya chakudya. Mwamtheradi, kulemera kwakukulu kumabwera chifukwa chodyera kapena kudya pamene sikofunikira. Zokonda ndizimene zimayambitsa kudya kwambiri komwe mumakhala ndi chilakolako chodya china (makamaka zinthu zokoma) ngakhale pamene simuli ndi njala. Symlin ingakuthandizeni kuthetsa vutoli.

Njira ina imene Symlin amagwira ntchito mwa iwe ndi ntchito ya m'mimba. Izi ndi zomwe mukugwiritsa ntchito mankhwalawa, mlingo umene chakudya chimachokera m'mimba kupita m'mimba mwaching'ono amachepa. Kudya chakudya ndi chakudya chokwanira chimaphatikizapo m'matumbo ang'onoang'ono, ndipo pambuyo pa njira zomwe mumayamba kumva njala ndikukonzekera kudya. Kodi chimachitika ndi chiyani pamene chakudya chimatengera nthawi yaitali kuti chifike ku chimbudzi? Zidzatenga nthawi kuti mukhale ndi njala motero mudzawonjezera nthawi pakati pa nthawi yanu ya chakudya.

Njira yachitatu ndi kudzera mu ntchito ya chiwindi. Zochita za chiwindi, Symlin amagwira ntchito poletsa kapena kuchepetsa kutuluka kwa glucagon ndi maphala. Iyi ndi hormone yomwe imayenera kumasula shuga m'magazi. Glucagon imathandiza chiwindi pakatembenuka kwa glycogen kuti shuga. Pa matenda a shuga omwe ali ndi mitsempha yambiri yamagazi, Symlin amathandiza kuthetsa vutoli polepheretsa kutuluka kwa shuga kwambiri pogwiritsa ntchito glucagon.

4. Kodi ndiyenera kuchita chiyani kamodzi koyambitsa jekeseni la Pramlintide? aasraw

Gwiritsani ntchito Symlin molondola chifukwa muyenera kuuzidwa ndi dokotala wanu. Tsatirani maulendo onse pa lemba lanu la mankhwala. Dokotala wanu angasinthe mlingo wanu kuti mupeze zotsatira zabwino kwambiri. Mukayamba kutenga Symlin mlingo wanu, mlingo wanu umatha kusintha. Musagwiritse ntchito mankhwala anu mu ndalama zazikulu kapena zing'onozing'ono kapena kwa nthawi yaitali kuposa momwe mwalangizira mankhwala anu. Kumbukirani, a Katemera wa hypodermic ziyenera kuchitidwa ndi katswiri kuti athetse mavuto aliwonse koma dokotala angakuphunzitseni momwe mungadzipirere kwanu.

Symlin imajambulidwa pansi pa khungu, pa nthawi yoyenera monga jekeseni yako ya mahomoni; komabe pa mlingo wosiyana kwambiri. Osakaniza mankhwala ndi insulini mu jekeseni lomwelo. Komanso, musadwale mankhwala anu ngati simukudziwa za izo chifukwa zingayambitse mavuto. Pezani mlingo kwa dokotala wanu kapena mutaphunzitsidwa momwe mungagwiritsire ntchito siritseni moyenera.

(1) Zimene mungachite musanagwiritse ntchito Symlin

Lolani wamankhwala anu kudziwa ngati muli ndi mankhwala enaake kapena mankhwala omwe ali mu Symlin. Yang'anani kutsogolera mankhwala kwa zigawo zikuluzikulu musanayambe kutenga mayendedwe anu.

Udziwitseni dokotala mankhwala alionse omwe simukuwalembera mankhwala omwe simukuwalemba. Angakhale vitamini, mankhwala a zitsamba kapena zakudya zowonjezera zakudya. Fufuzani chenjezo la Mvetserani kwa mankhwalawa kuti muwone ngati mukuloledwa kugwiritsa ntchito limodzi ndi mankhwala ena monga Symlin. Dokotala wanu angagwiritse ntchito pepala kuti apeze mlingo woyenerera wa Pramlintide kwa inu kapena ayi / akhoza kukutsatirani mosamala za zotsatirapo zilizonse.

Ngati muli ndi chithandizo chilichonse cha kulera, mankhwala opweteka ndi opha ululu, otengedwa pamlomo, muyenera kuwagwira maola awiri kapena awiri musanagwiritse ntchito Symlin.

Adziwe dokotala wanu ngati muli ndi pakati, kapena mukatenga mimba mukamagwiritsa ntchito mankhwalawa kuti mupewe mavuto alionse m'tsogolomu.

Werengani ndi kumvetsetsa malangizo ndi malangizo a ntchito. Muyenera kuwerenga ndi kumvetsetsa ndikutsata ndondomeko ya mankhwala. Kodi kufufuza ndi kumvetsa momwe mungagwiritsire ntchito mankhwalawa, zomwe muyenera kuyembekezera mutagwiritsa ntchito komanso zotsatira zowopsa za Symlin. Pezani zonse zomwe mukufunikira panthawi ya mankhwala monga singano. Pezani chithandizo cha katswiri kuti mumvetse mitundu yosiyanasiyana ya singano ndi yomwe ili yabwino kwa inu. Werengani malangizo ndi malangizo othandizira olemba mankhwalawa. Komanso, onetsetsani kuti mumvetsetsa pamene mukufuna kukhazikitsa singano yatsopano ndikulola adokotala akuwonetseni momwe mungagwiritsire ntchito.

Musanayambe kulandira jekeseni wa Pramlintide, nthawi zonse yang'anani yankho lanu ndikuonetsetsa kuti liri bwino komanso losapanga mtundu. Ngati mitambo, yakuda, yofiira kapena ili ndi tizilombo tomweyi, ingathe kutsirizidwa kapena kutetezeka kugwiritsira ntchito. Onetsetsani tsiku lomalizira pa lemba ndipo ngati simunathetsere, funsani dokotala kuti adziwe ngati zili zotetezeka.

Sambani jekeseni. Zikhoza kukhala paliponse pa ntchafu kapena paliponse ponseponse atalangizidwa ndi mankhwala anu. Konzani malowa poyeretsa ndi kusamba poyamba. Derali liyenera kukhala ndi masentimita awiri kuchokera pamene mukufuna kupanga jekeseni wa insulini.

(2) Symlin mlingo wokwanira

Symlin yakhala yothandiza kwambiri kwa anthu omwe ali ndi matenda a shuga a 1. Komabe, izi zingatheke pokhapokha ngati zogwiritsidwa ntchito moyenera komanso moyenera. Pali njira zingapo zopangira ntchito ya Symlin. Choyamba ndi kuyamba pazing'ono. Kuti muzindikire ndikudziwa zolondola Mlingo wa pramlintide zomwe zimagwirira ntchito kwa inu, muyenera kuyamba pansi ndipo mwinamwake kuonjezera kuchuluka kwa mzere. Yambani ndi kugwiritsa ntchito mankhwala pakudya kamodzi pa tsiku. Mwachitsanzo, mungayambe kugwiritsa ntchito kadzutsa. Mutangomaliza kuyeza mlingo umenewo ndikuzindikira kuti palibe zotsatirapo zovuta, yesetsani kugwiritsa ntchito njira yofananayo pa zakudya zonse. Onani kuti mlingowo sayenera kusiyana ndi chakudya chimodzi. Muyenera kutenga mlingo womwewo mosasamala kanthu kapena kuti mumakonzekera kuchuluka bwanji.

Chinthu chotsatira ndicho kudziwa mlingo woyenera. Muyenera kuyamba ndizing'ono zomwe zili 15 mcg ngati mukugwiritsa ntchito cholembera kapena 2 ku maselo a 3 ngati mukugwiritsa ntchito sitiroko. Gwiritsani ntchito masiku pafupifupi atatu ndikuwonjezerapo ndi 15 mcg mpaka mutapeza mankhwala ochiritsira.

Chiwerengero choyenera cha Symlin chikhoza kupangitsa mimba yako kuwawa kwa 15 kwa 30 maminiti atalandira jekeseni, kapena mukhoza kukhala ndi shuga ya m'magazi otsika kwa maola angapo. Ngati simukusowa zina mwa izi, muyenera kuwonjezera mlingo wanu. Muyenera kuwonjezera mlingo ndi ntchito yaitali. Pambuyo pa nthawi yaitali ntchito ngati miyezi kapena zaka, mukhoza kuyamba kulekerera Symlin, ndipo muyenera kutenga ndalama zochepa kuti mukwaniritse zotsatira.

Mlingo wokwanira uli motere;

15 microgram pang'onopang'ono, jekeseni nthawi yomweyo chakudya chilichonse chachikulu

-Mayeso otchedwa hormone (kuphatikizapo premixed insulini) ayenera kuchepetsedwa ndi zisanu mazana asanu.

-Kupweteka kumayenera kukwezedwa kuwonjezereka kwina (30, 45, kapena makumi asanu ndi limodzi mcg) kamodzi kokha kusachiritsika kwakukulu kwa kachipatala kwachitika kwa masiku osachepera atatu.

-Koma kusanza kwakukulu kumapitirizabe kuchuluka kwa mlingo wa dose makumi asanu ndi zisanu kapena zisanu ndi umodzi za mlingo wa mlingo, mlingowu uyenera kuchepetsedwa kwa 30 micrograms.

-Koma mayeso a microgram makumi atatu saloledwa, mapeto ayenera kuganiziridwa.

Gwiritsani ntchito chithandizo kwa odwala omwe ali ndi vuto limodzi la matenda a polygenic. Bungwe la World Health Organization limagwiritsa ntchito chithandizo chamankhwala cha mahomoni tsiku ndi tsiku ndipo World Health Organization silingakwanitse kukwaniritsa zofuna za aldohexose ngakhale kuti ndibwino kwambiri thandizo lachipatala la hormone.

Kawirikawiri Mayi akuluakulu a matenda a polygen monga mtundu 2:

60 microgram pang'onopang'ono, jekeseni nthawi yomweyo chakudya chilichonse chachikulu

Comments:

-Mayeso otchedwa hormone (kuphatikizapo premixed insulini) ayenera kuchepetsedwa ndi zisanu mazana asanu.

-Kuyenera kupatsidwa mankhwala okhudzana ndi zowawa zapakati pa makumi asanu ndi limodzi kapena makumi awiri mphambu makumi awiri (1) pa chakudya chambiri chisanayambe kuchepetsa kunyowa kwapadera kwa masiku osachepera atatu.

-Koma kusanza kwakukulu kumapitirirabe pa mlingo wa zana ndi makumi awiri wa microgram, mlingowu uyenera kuchepetsedwa mpaka makumi asanu ndi limodzi.

Zinsinsi Zambiri za 7 Zokhudza Kugwiritsa Ntchito Ntchito, Mukudziwa

(3) Pambuyo pobaya jekeseni wa Pramlintide

Samalani kuti musalole kuti shuga wanu ukhale wotsika kwambiri. Katemera wotsika kwambiri (hypoglycemia) ukhoza kuchitika pakapita maola atatu kamodzi kake kamene kamayambitsa jekeseni wa Symlin. Ngati muli ndi hypoglycemia yamphamvu ndipo simungathe kudya kapena kumwa, gwiritsani ntchito jekeseni wamkati. Dokotala wanu adzatsitsa kapangidwe kakang'ono ka jekeseni kachitetezo chamkati ndikuwonetsani momwe mungagwiritsire ntchito.

Onetsetsani zizindikiro za shuga yapamwamba (hyperglycemia) ngati ludzu lolemekezeka, kuwonongedwa kwakukulu, njala, pakamwa youma, fruity kupuma kununkhira, kugona, khungu louma, kuona bwino, ndi kuwonongeka.

Onetsetsani shuga wanu mosakayika nthawi zonse zovuta, kuyenda, matenda, opaleshoni kapena zovuta zachipatala, kuchita masewera olimbitsa thupi, kapena kumwa mowa kapena kudya zakudya. Zinthu izi zidzakhudza miyeso yanu ya aldohexose, ndipo chikhumbo chanu chikhoza kuphatikizapo kusintha.

Gwiritsani ntchito singano ndi syringe yosangika kamodzi kokha. Tsatirani malamulo aliwonse a boma kapena malamulo oyendetsera zitsulo komanso masipiringi. Gwiritsani ntchito zipangizo zochotsera zida zowonongeka (funsani mapiritsi anu kulikonse kumene mungapangire njira imodzi ndi njira yowataya). Sungani zidazi kuti zisatheke kwa achinyamata ndi ziweto.

Musagwirizane nawo cholembera cha digiri ya jekeseni ndi munthu wina. Kugawana jekeseni wa Pramlintide zolembera zidzathandiza matenda monga matenda a chiwindi kapena kachilombo ka HIV kuti apite kuchokera kwa munthu mmodzi yemwe ndi owopsa.

Itanani dokotala wanu ngati muli ndi nseru yaikulu yomwe imakhala masiku ambiri. Izi zikhoza kukhala chisonyezero chakuti mlingo wanu ndi wapamwamba kwambiri

Symlin ndi gawo limodzi la mapulogalamu omwe amaphatikizapo kudya, kuchita masewero olimbitsa thupi, kuyang'anira kulemera, kuyesayesa kwa nthawi zonse, ndi thandizo loyamba la mankhwala. Khalani ndi ndondomeko ya tsiku ndi tsiku kamodzi koyambitsa jekeseni wanu ndikuyesera shuga. Ndizofunikira kuti mukonzekere chakudya chanu ndi zochitika zanu. Simungakhale okonzeka kupitiriza kugwiritsa ntchito Symlin ngati simukutsatira malangizo a mlingo.

Pramlintide idzakuchepetsani chimbudzi chanu, ndipo ziyenera kutenga nthawi yaitali kuti thupi lanu lizitha kuyamwa mankhwala alionse omwe mukuwatenga. Pewani kumwa mankhwala alionse pakamwa pakapita ola limodzi kapena maola awiri mutagwiritsa ntchito Symlin.

Pewani kumwa mowa. Adzatsitsa shuga wanu.

Zomwe mungathe kuti mukhale ndi zotsika kwambiri shuga ndizowonjezereka ngati:

  • musamatsatire malangizo a wothandizira anu kuti muchepetse kugwiritsa ntchito mahomoni musanadye
  • gwiritsani ntchito SYMLIN yowonjezera kapena mahomoni ochuluka kuposa momwe akulamulidwa ndi wogulitsa wanu
  • sintha mlingo wa homoni popanda kudziwa dokotala wanu
  • idyani chakudya chochepa kusiyana ndi chakudya chanu chachizolowezi
  • ali odwala ndipo sangathe kudya
  • ndizowonjezera zowonjezera kuposa nthawi zonse
  • Mukhale ndi khofi ya shuga musanayambe kudya
  • kumwa mowa

Kusiyanitsa kwa chithandizo chamankhwala!!!

SYMLIN thandizo lachipatala liyenera kuthetsedwa ngati liripo:

  • Kusamalidwa kofunikira kwambiri kwachipatala.
  • Kusagwirizanitsa ndi kudziyendetsa bwino pa shuga la magazi.
  • Kusagwirizana ndi mazira a mahomoni amasintha.
  • Kusagwirizana ndi oyang'aniridwa nthawi zonse othandizira kapena kulangizidwa kuchipatala.

5. Ndani Sagwiritse Ntchito Pramlintide? aasraw

Ngati muli ndi chidziwitso chosadziwika, ndiye kuti matenda a shuga a Pramlintide sangakhale a inu. Kulephera kudziwa ngati glucose ikusiya kungakhale koopsa chifukwa cha chitsimikizo chokwanira cha hypoglycemia ndi Pramlintide.

Ngati mwapezeka kuti muli ndi gastroparesis, simungakhale woyenera kupita ku Pramlintide chifukwa cha kuchedwa kwa m'thupi mwachangu komwe kumachokera. Kupanga mankhwala sikunayesedwe kotetezeka kwa ana omwe sanabadwe kapena amayi; Choncho ngati muli ndi pakati kapena akuyamwitsa, ndiye kuti Pramlintide sungaperekedwe kwa inu.

Kupititsa patsogolo kumathandiza kwambiri kuchepetsa shuga m'thupi mwathu, ndipo pang'onopang'ono muyenera kuthandizidwa kuti mutenge Pramlintide.

Musanayambe kutenga Pramlintide, dokotala wanu ayenera kumvetsa ngati:

  • Musamadziwe bwino za hypoglycemia
  • Ali ndi pakati, amakhala ndi pakati kapena akuyamwitsa
  • Ndizovuta kwa metacresol
  • Khalani kapena muli ndi gastroparesis
  • Akumwa mankhwala opatsirana kapena mankhwala

6. Zochitika zosiyana kuchokera ku Pramlintide aasraw

Malingana ndi zotsatira zake zofunika, Pramlintide shuga (chinthu chogwiritsidwa ntchito chotchedwa Symlin) chingayambitse zina zosayenera. Ngakhale kuti zonsezi sizitha kuchitika, ngati zikuchitika zikufunika kuchipatala.

Yang'anani mwamsanga ndi dokotala ngati zotsatira za zotsatirazi zikuchitika mukatenga Pramlintide:

Zowonjezera Zambiri

  • nkhawa
  • zovuta
  • Kuwombera kozizira
  • chisokonezo
  • Khungu lozizira kwambiri
  • Zovuta ndi kumeza
  • chizungulire
  • njala yochuluka
  • mawu osokoneza
  • Kukhazikika mu chifuwa

Zina mwa zotsatira za Pramlintide zikhoza kuchitika zomwe samafuna kuchipatala. Zotsatirazi zimatha kuchoka pakapita mankhwala pamene thupi lanu limasintha mankhwala. Komanso, aluso anu a zaumoyo onse ndi okonzeka kukuuzani za njira zomwe zingasiyire kapena kuchepetsa zotsatirapo za zotsatirazi. Funsani mankhwala anu ngati zotsatira za zotsatirazi zikupitirira kapena zikukuvutitsani kapena ngati muli ndi mafunso awa:

Wodziwika

  • Zovuta ndi kusuntha
  • Kutaya chilakolako
  • kuwonda
  • Zochepa Zosagwirizana
  • Kusakanikirana
  • Kuuma kapena kupweteka kwa mmero
  • Kusokonezeka
  • Liwu limasintha

7. Kutsiliza aasraw

Pramlintide ndi digiri yoyanjana ndi amylin analog yomwe idzagwiritsidwa ntchito ndi nthawi ya ma hormone pakuthandizidwa ndi mtundu umodzi ndikukonza matenda awiri a polygen. Odwala omwe ali ndi matenda awiri a mitundu ya polygenic, Pramlintide imatha kupezeka kwa antidiabetic monotherapy, Glucophage monotherapy, kusakaniza sulfonylurea ndi Glucophage, kapena kusakaniza antidiabetic, Glucophage ndi hormone. Thandizo la zamankhwala ndi Pramlintide limachepetsa A1C ndi zero.2% mpaka 0.6% ndipo chifukwa cha 2-hours postprandial aldohexose ndi atatu.4 mpaka asanu mmol / L. Pakati pa maphunziro a chaka cha 1, thandizo lachipatala la Pramlintide linachepetsa kulemera ndi kudzichepetsa; Komabe, mu sabata limodzi la 52, chizindikiro chotseguka, kulemera kwayesero koyeso kunabwerera ku miyeso yoyamba. Pali digiri yoyanjana yamakono yomwe ikuyesa mphamvu Kutaya kwa thupi kwa Pramlintide wothandizira.

Pramlintide ili ndi mbiri yabwino yoteteza chitetezo ndi zotsutsana kwambiri. Kudandaula kwachizolowezi ndizochitika zovuta nthawi zonse. Kuchepetsa mpata wa hypoglycemia, kuchotsedwa kwa hormone yoyamba ndi mazana asanu ndi zana ndi kutseka aldohexose kuyang'ana kumatetezedwa.

Komabe mwazonse, Pramlintide acetate amawoneka ngati kuwonjezera koyenera ngati mawere a glucose samayankha hormone yekha. Mwachangu pafupipafupi pamimba, zimathandiza kuthetsa makasitomala apamwamba kuposa mahomoni okha. Kupanga mankhwalawa kumapangitsa kuti poizoni azitha kuwononga mankhwala omwe ali nawo mbali ya thupi la neoplastic cell lines yomwe imakhala ndi p53 zakutchire kapena mutant. Choncho, Pramlintide ikhoza kukhala yodalirika yothandizidwa ndi khansa ya thupi.

Khalani maso chifukwa cha zizindikiro za kuchepa kwa shuga ndipo nthawi zonse muyang'ane miyeso musanayambe kudya kamodzi. Odwala ambiri pa SymlinPen ndi okondwa kumeneko. Kambiranani ndi dokotala nthawi zonse musanayambe mlingo wanu wa Pramlintide kapena mukufuna kusiya mankhwala aliwonse panthawi yomwe mumatenga Pramlintide.

Mtengo wa Pramlintide ukhoza kukhala wosiyana ndi wopanga wina kapena wogulitsa wina koma nthawi zonse umatsimikizira kuti iwe Gulani Chilichonse kuchokera opanga odalirika. Pali ogulitsa ogulitsa osiyana omwe alipo pa intaneti koma samalani kuti musagule mankhwala otsika kapena otha msinkhu. Pezani kafukufuku wanu wamsika kuti mupeze ogulitsa abwino a Pramlintide ozungulira inu. Sankhani wogulitsa ndi mitengo yabwino komanso yomwe imapereka nthawi yochepa kwambiri. Dokotala wanu akhoza kukhala munthu wabwino kwambiri kuti akuthandizeni kupeza mankhwala abwino kwambiri ndi kwa wogulitsa wodziŵa zambiri.

Zothandizira

  1. Younk, LM, Mikeladze, M., & Davis, SN (2011). Kupanga mankhwala ndi chithandizo cha matenda a shuga: kubwereza deta kuyambira pachiyambi. Akatswiri pankhani ya pharmacotherapy, 12(9), 1439-1451.
  2. Herrmann, K., Frias, JP, Edelman, SV, Lutz, K., Shan, K., Chen, S., ... & Kolterman, OG (2013). Njira Zowonjezera Zowonongeka kwa Glycemic ndi Thupi la Thupi la Odwala Ndi Mtundu Womwe Ndikumasamalira Shuga Mellitus Akupitirizabe Kugwiritsa Ntchito Njira Yopatsirana Yopatsirana Mwachangu. Mankhwala apamwamba, 125(3), 136-144.
  3. Herrmann, K., Brunell, SC, Li, Y., Zhou, M., & Maggs, DG (2016). Zotsatira za matenda nthawi yayitali pa zotsatira za pramlintide mu mtundu wa 1 shuga: posanthula polemba mayesero atatu a kuchipatala. Kupititsa patsogolo pa mankhwala, 33(5), 848-861.

Kusiya ndemanga

Shangke Chemical ndi makampani apamwamba kwambiri omwe amagwiritsa ntchito mankhwala omwe amathandiza kwambiri. Pofuna kuyendetsa khalidweli panthawi yopanga, akatswiri ambiri odziwa bwino ntchito, makina oyambirira kupanga zipangizo komanso ma laboratori ndi mfundo zofunika kwambiri.

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