Chidule cha Lactoferrin

Lactoferrin (LF) ndi chakudya chachilengedwe chokhala ndi mkaka wa mamiliyoni ndikuwonetsa zinthu zotsutsana ndi tizilombo. Kuyambira pomwe adayamba mu 60s, pakhala pali maphunziro ambiri kuti akhazikitse kuchuluka kwa kuchiritsa kwa glycoprotein ndi udindo wake pakulimbana ndi chitetezo chamthupi.

Ngakhale ana ang'onoang'ono amatha kupeza zowonjezera kuchokera poyamwa amayi awo, lactoferrin ufa wopangidwa ndi malonda amapezeka pazaka zonse.

1. Kodi Lactoferrin ndi chiyani?

Lactoferrin (146897-68-9) ndi glycoprotein womanga wachitsulo wa banja lolo. Protein iyi ili ndi ma antibodies ambiri ndipo imapezeka mu mkaka wa anthu ndi ng'ombe. Kuphatikiza apo, ndimachotseredwe ambiri obisika mwachilengedwe monga misozi, malovu, madzi amphuno, madzi a kapamba, ndi bile. Thupi limatulutsa glycoprotein mwanjira yothandizira kupukusa.

Musanapange a lactoferrin mugule, tengani tsamba kudzera pamawu awa kuti muwone ngati chowonjezeracho chilidi.

Mafuta ochulukirapo a lactoferrin amapezeka mu colostrum, womwe ndi madzi oyamba kwambiri pokhapokha atabereka. Imasungidwa mkaka m'masiku awiri kapena atatu atabadwa. Ngakhale zobisika za colostrum zikuyandikira, kuchuluka kwa lactoferrin kudzapezekabe mkaka wosinthika ndi mkaka wokhwima.

Ndiye, mumachotsa bwanji lactoferrin kuchokera ku bovine colostrum?

Ndiloreni kuti ndikupatseni njira yodzipatula ya lactoferrin.

Gawo loyamba limaphatikizapo kulekanitsa Whey kuchokera mkaka. Whey ndimadzulu amadzimadzi amene amakhalapo pambuyo poti kupindika kapena mkaka wosakanizika ndi acid acid. Njira yodzipatula imagwiritsa ntchito ma hydrophobic mogwirizana ndi ma chromatography ndi ma ion-exchange chromatography omwe amatsatiridwa ndikutsatiridwa motsatizana ndi njira zamchere.

Bovine colostrum imachokera ku ng'ombe. Muli mapuloteni, ma antibodies, mchere, mavitamini, chakudya, komanso mafuta. Magawo awa atsimikizira phindu la achire la colostrum, motero, akukopa chidwi pakati pa asayansi ofufuza zamankhwala.

Popeza kuti zinthu za lactoferrin zimachepera nthawi yotsala itatha, gawo lina limalimbikitsa mwana wakhanda. Mwachitsanzo, mwachitsanzo, LF wamba akangobadwa ili pafupi 7-14mg / ml. komabe, ndende imatha kutsikira pafupifupi 1mg / ml ndi mkaka wokhwima.

Ngati mukufuna kuphatikizanso mu lactoferrin wa immunological, muyenera ku banki pazowonjezera za bovine colostrum.

Mafuta opangidwa ndi lactoferrin opangidwa ndi makampani ogulitsa ndi chipangizo cha bovine colostrum. Komabe, malonda akhala nkhawa kwa anthu ena omwe akuwoneka kuti akhumudwitsidwa chifukwa chodwala matendawa. Chabwino, ndikutsimikizireni kuti izi sizachilendo. Kuphatikiza apo, zakudya zina za ana za lactoferrin ndizopanga za mpunga wopangidwa ndi majini, mokomera anthu omwe ali osalolera lactose.

Kodi Zophatikiza Zophatikiza ndi Ziphuphu za Lactoferrin Zotani Kwa Akuluakulu Ndi Ana Omwe

2. Chifukwa chiyani kugwiritsa ntchito Lactoferrin Powder monga Zowonjezera, Zopindulitsa za Lactoferrin zilipo?

Kuwongolera Ziphuphu

Cutibacterium ndi propionibacterium amachititsa ziphuphu zambiri. Lactoferrin imagwira ntchito kuti ithetse mabakiteriya achitsulo ndikuchepetsa zotsatira zake.

Nthawi zina, ma radicals omasuka komanso mitundu ya mpweya yomwe imagwira ntchito imathandizira kuti masoka apangidwe komanso kuwonongeka kwa DNA. Chifukwa cha kupsinjika kwa oxidative, kutupa kumatha kuchitika komanso kukhudza kukula kwa ziphuphu. Malinga ndi asayansi ofufuza, lactoferrin ndi anti-oxidant, chifukwa chake, amatha kupikisana ndi ma radicals aulere.

Kutenga lactoferrin pambali pa vitamini E ndi zinc kumachepetsa zilonda zam'mimba ndi comedones pakangotha ​​miyezi itatu.

Kuphatikiza apo, kutupa kumayambitsa mwachindunji mapangidwe a ziphuphu ndi cysts mwa kutseka ma pores. Ntchito zotsutsa-zotupa za lactoferrin zimatsimikizira kuchiritsidwa kwa zotupa.

Akatswiri a zamankhwala amatsimikizira kuti thanzi lanu la m'matumbo limawonetsa khungu lanu. Mwachitsanzo, ngati mawonekedwe anu am'mimba ndi otupa kapena osapatsa thanzi, kugwiritsa ntchito mitundu yonse ya mawonekedwe kapena mawonekedwe apadziko lapansi sangathetse kutupa, khungu, masewera, kapena chikanga. Kutenga lactoferrin kutulutsa kachilombo koyambitsa kupukusa pakulimbitsa thupi ndikumalimbikitsa ntchito za zomera zofunikira za Bifidus.

Kupatula pochiza ziphuphu, lactoferrin adachepetsa zizindikiro za psoriasis ndikuthandizira kuchira kuchokera ku zilonda zam'mapazi za neuropathic, zomwe zimapezeka kwambiri pakati pa odwala matenda a shuga.

Wothandizira Anti Microbial

Kafukufuku wosawerengeka amatsimikizira kuti Lactoferrin (LN) imalepheretsa mavairasi, mabakiteriya, majeremusi, ndi matenda oyamba ndi fungus kuukira thupi. pulojekitiyo imagwira ntchito pomanga ma ma virus, kupangitsanso mawonekedwe awo maselo, ndikutseka ma cell receptor.

Pakufufuza kwina, asayansi adawona kuti lactotransferrin (EA anali othandiza kwambiri kuteteza kachilombo ka herpes kuposa mtundu wa anthu. Kafukufuku wa in vitro akuwonetsanso kuti chowonjezera ichi chimayendetsa bwino zovuta za HIV.

Mlingo wapamwamba pang'ono, lactoferrin imagwira ntchito kuti iwongolere matenda a Hepatitis C. Malinga ndi Kafukufuku wa Hepatology, mankhwalawa amawonjezera mawu a interleukin-18, puloteni wothandizira kuyendetsa kachilombo ka Hepatitis C. Kuti muchite bwino, odwala ayenera kudya pafupifupi 1.8 mpaka 3.6 magalamu a mankhwala patsiku. Cholinga chake ndi chakuti Mlingo wochepetsetsa wa lactoferrin sangachititse zosiyana zamagulu anu.

Pali malingaliro, omwe amalingalira LF ngati chithandizo cha matenda a helicobacter pylori. Mukakonza zowonjezerazo ndi mankhwala anu achilonda, mwayi ndiwakuti mankhwalawa adzakhala othandiza. Izi zakhala mkangano wamafupa pakati pa ofufuza chifukwa ambiri amaganiza kuti lactoferrin ufa wogwiritsa ntchito ukakhala wosavomerezeka popanda kupezeka mankhwala.

Kuwongolera kwa Iron Metabolism

Lactoferrin sidzangoyendetsa kuchuluka kwa chitsulo mthupi komanso kuwonjezera kuyamwa kwake.

Pakhala pali kafukufuku wopitiliza kuchipatala yemwe amafuna kuyerekeza mphamvu ya LF posiyanitsa ndi kufera kwa kuchepa kwa magazi m'thupi pazakudya zapakati pa mimba. Kuchokera pakuzengedwa, lactoferrin adakhala wamphamvu kwambiri polimbikitsa mapangidwe a hemoglobin ndi maselo ofiira amwazi.

Amayi omwe amadya glycoprotein ali ndi mulingo woyenera kwambiri wazitsulo wokhala ndi zotsatira zoyipa. Lactoferrin amagwira ntchito kuti achepetse kutayika kwa padera, kubereka asanabadwe, komanso kubereka otsika.

Chifukwa chake, zikuwonekeratu kuti ndi chowonjezera chowonjezera cha amayi omwe ali ndi pakati komanso azimayi azaka zoyambira kubereka omwe amataya zitsulo zina akakhala kuti ali ndi vuto. Masamba komanso opereka magazi pafupipafupi atha kupindulanso ndi lactoferrin zowonjezera.

Thirakiti Lathanzi Lathanzi

Lactoferrin khanda lothandizira limatulutsa ndipo limapangitsa kuti m'matumbo mukhale athanzi. Amachotsa mabakiteriya oyipa, omwe amachititsa kutupa. Mwachitsanzo, ma virus amenewa amabwera chifukwa cha gastroenteritis yambiri ndi enterocolitis, yomwe imawononga makhoma am'mimba ndikupangitsa kuti munthu asamwalire msanga. Ngati pazifukwa zina, mwana wanu samayamwa, ndikofunikira kuti musinthe bovine lactotransferrin (LTF).

Kodi Zophatikiza Zophatikiza ndi Ziphuphu za Lactoferrin Zotani Kwa Akuluakulu Ndi Ana Omwe

3. Ubwino wa Lactoferrin pa Khanda

Lactoferrin khanda lothandizira limalepheretsa kukula kwa tizilombo m'matumbo a makanda akhanda. Ma virus amenewa ndi monga Escherichia coli, Bacillus stearothermophilus, Staphylococcus Albus, Candida albicans, ndi Pseudomonas aeruginosa. Kafukufuku wambiri akutsimikizira kuti kudya tsiku lililonse lactoferrin wowonjezera kumachepetsa mwayi wa makanda a noroviral gastroenteritis mu makanda.

Adakali m'matumbo, LF imalimbikitsa kufalikira kwa maselo amkati mwa ma endothelial pomwe akuwonetsa kukula kwa masentimita am'mimba. Chifukwa chake, zikuwonekeratu kuti kuphatikiza kwa lactoferrin kungakhale mankhwala othandizira owonongeka m'matumbo.

Kuyamwitsa ndiko gwero lalikulu lachitsulo kwa ma neonates. Komabe, akatswiri azachipatala amalimbikitsa kuti kuwonjezera pazitsulo zowonjezera ndizofunikira popeza mkaka wa m'mawere ulibe zochepa za mcherewu.

Ndiloreni ndifotokoze chifukwa chake LF ndi njira yabwino yothandizira ana asanakonzekere ndi makanda obadwa ndi otsika otsika. Nthawi zambiri, gululi limatengeka kwambiri ndi vuto la kuchepa magazi m'thupi. Kuyang'anira khansa ya khansa ya lactoferrin kumakulitsa hemoglobin ndi maselo ofiira amwazi mu toddler. Komanso, kafukufuku akuwonetsa kuti kuwonjezera pazitsulo kumathandizira khanda kukula kwamitsempha.

Nthawi zina, mabakiteriya oyipa ngati E.coli amadya chitsulo cham'mimba. Kutenga lactoferrin kumaphwanyaza kachilombo kakang'ono kachitsulo ndikuwawononga ndikumawonetsetsa kuti wolandirayo alandila michere yonse yomwe ilipo.

LF imathandizira kwambiri pakukula kwa chitetezo cha mthupi cha mwana. Zina mwazomwe amagwiritsa ntchito lactoferrin ufa zimaphatikizira kuchuluka kwa ntchito za macrophages, ma immunoglobulins, ma cell a NK, ndi ma lymphocyte a T, omwe amachititsa kuti chitetezo cha neonatal chitenthe. Zowonjezera, kuphatikiza LF kumachepetsa kukhudzika kwa ziwopsezo zam'thupi.

4. Kodi Lactoferrin Amasintha Bwanji Thupi Lathanzi?

Zapakatikati pakati pa Ntchito za Adaptive and Innate Immune

Pakulimbana kwa chitetezo chamthupi, lactoferrin imachita m'njira zingapo. Mwachitsanzo, imathandizira zochitika za maselo akupha achilengedwe (NK) ndi ma neutrophils. Mapuloteniwo amawonjezera phagocytosis ndipo amachititsa kuwonjezeka kwa macrophages.

Poyankha moyenera, LF imathandizira pakusintha kwa ma T-cell ndi B-cell. Pankhani yakutseguka kwa mauthenga, ziwalo zamkati ndi zosinthika m'thupi zimaphatikizana kuthana ndi zomwe zimachitika.

Lactoferrin amawongolera kupanga kwa pro-kutupa cytokines ndi interleukin 12, komwe kumawonetsa chitetezo kumbuyo kwa tizilombo toyambitsa matenda.

Amagwiritsa ntchito mu Systemic Inflammatory Response Syndrome (SIRS)

Udindo wa lactoferrin ufa popewa mitundu ya mpweya yomwe imagwira (ROS) yakhala yofunikira pophunzira ubale wake ndi kutukusira kwa khansa. Kuwonjezeka kwa ROS kumatanthauzira ku chiwopsezo chachikulu cha zotupa chifukwa cha apoptosis kapena kuvulala kwa ma cell.

Chitetezo chokwanira

Mphamvu yotsutsa-tizilombo tating'onoting'ono ta lactoferrin imadula mabakiteriya, tizilombo, tiziromboti, ndi matenda oyamba ndi fungus.

Microbes imakula bwino ndipo imadalira chitsulo kuti ikule ndi kupulumuka. Akaukira wolowa, LF imalepheretsa kugwiritsa ntchito kwawo chitsulo.

Pa gawo loyambirira la matenda, lactoferrin (LF) amalimbana ndi zoyambitsa zakunja m'njira ziwiri zotsimikizika. Mapuloteniwa amatha kutseka ma cellular receptor kapena kumangirira ku virus, potero, kupewa kuti alowe nawo. Zochita zina zotsutsana ndi tizilombo tating'onoting'ono ta lactoferrin zimaphatikizira kuchepetsa njira ya pathogen kapena kutsekeka kagayidwe kazachilengedwe.

Kafukufuku wambiri amawongolera ufa wa lactoferrin pakuwongolera kachilombo ka Herpes, kachilombo ka HIV, Humpatitis C ndi B, fuluwenza, ndi hantavirus. Kuphatikiza apo, zowonjezera zinalepheretsa kuchuluka kwa alphavirus, rotavirus, papillomavirus ya anthu, ndi ena angapo.

Nthawi zina, Lactoferrin sangatulutse matenda onse koma musakayikire kuti ichepetsa kuopsa kwa kuchuluka kwa ma virus omwe alipo. M'maphunziro am'mbuyomu, LF idachita bwino poletsa Sse pseudovirus. Popeza SARS-CoV-2 imagwera kalasi yomweyo SARS-CoV, pali kuthekera kwakuti lactoferrin ingachepetse kuvulazidwa kwa COVID-19.

Ngakhale akatswiri azachipatala omwe amathandizira kuti chitetezo cha mthupi lanu chiteteze chitetezo sichiteteza munthu ku coronavirus, kuphatikiza kwa lactoferrin kumathandizira pankhondo. Kupatula apo, akatswiri omwewo adawona kuti okalamba ndi anthu omwe ali ndi chitetezo chochepa kwambiri ali pachiwopsezo chachikulu chotenga COVID-19.

5. Kugwiritsa Ntchito kwa Lactoferrin Powder ndi Kugwiritsa Ntchito

Lactoferrin chochuluka ufa ulipo kwa asayansi ofufuza ndi akatswiri omwe akufuna kukhazikitsa phindu lawo lachipatala m'thupi la munthu. Ili ndi chiyembekezo chokwanira popewa matenda, zopatsa thanzi, chakudya komanso mankhwala antiseptics, komanso zodzola.

Pakuwunikira kwanu komanso kuyesa kwa labu, onetsetsani kuti mwayambitsa gululo kuchokera kwa othandizira a lactoferrin ufa.

Lactoferrin ufa gwiritsani mwana mkaka wa ufa

Mwana wakhanda ufa amawongolera mosalekeza kuwonetsa kuyamwa kwamkaka weniweni kuchokera kwa mayi. Lactoferrin ndiye mapuloteni awiri amodzi mu mkaka wa make wa mayi. Ndiwotchuka chifukwa chobweretsa zabwino zamtundu uliwonse kwa khanda kuphatikiza ndikumanga chitsulo pofuna kupewa chitetezo chokwanira, kupewa khansa, komanso kulimbikitsa mafupa athanzi pakati pa ena.

Lactoferrin ndi mbali imodzi ya mkaka woyamba wamayi womwe umadziwika kuti colostrum. Colostrum imakhala ndi pafupifupi kawiri pa mililita imodzi monga mkaka wa m'mawere wokhwima. Izi zikutanthauza kuti ana ang'onoang'ono kwambiri amafunika kuchuluka kwa lactoferrin kuti atukuke bwino.

Kupititsa patsogolo chitetezo chamwana wakhanda kumachirikizidwa ndi gawo la Lactoferrin mu wakhanda. Mapuloteniwa amagwira ntchito yofunika kwambiri chitetezo cha m'thupi cha mwana ndipo amayimira chitetezo chokwanira cha anti-viral and anti-microbial immune system. Njira yotsutsa-tizilombo tating'onoting'ono imabweretsa kwambiri kutulutsa kwa ayoni, komwe ndi kofunikira kwambiri pakukula kwa bakiteriya. Kuphatikiza apo, lactoferrin imakhulupiriranso ngati antioxidant yomwe ingalimbitse chitetezo cha mthupi poyambitsa kusiyanitsa, kuchuluka, komanso kuyambitsa maselo chitetezo.

Kodi Zophatikiza Zophatikiza ndi Ziphuphu za Lactoferrin Zotani Kwa Akuluakulu Ndi Ana Omwe

6. Zotsatira zoyipa za Lactoferrin

Chitetezo cha LF chimayenda pazinthu zochepa.

Mlingo wambiri wa Lactoferrin ukhoza kukhala wamtambo. Mwachitsanzo, pamene mankhwalawo amachokera mkaka wa ng'ombe, mutha kumudya bwino chaka chonse. Komabe, pamene mankhwalawo amachokera ku mpunga, mwayi wake ndikuti kuwonjezeka kwa masabata awiri kungayambitse mavuto ena.

Zotsatira zoyipa za lactotransferrin (LTF) zimaphatikizapo;

  • kutsekula
  • Kutaya njala
  • Ziphuphu za khungu
  • kudzimbidwa
  • Chills

Mosiyana ndi mankhwala othandizira ambiri, lactoferrin ndiyotetezeka kwa amayi oyembekezera ndi oyamwitsa.

Kuti tidutse zotsatira zoyipa za lactoferrin, mulingo woyambira pakati pa 200mg ndi 400mg tikulimbikitsidwa. Muyenera kutenga miyezi iwiri kapena itatu motsatizana. Nthawi zina, nthawi imatha kupitirira miyezi isanu ndi umodzi.

7. Ndani angapindule ndi Lactoferrin?

Amayi

Lactoferrin amapindulitsa mayi ndi khanda.

Munthawi ya bere, kupereka izi kumathandizanso kukula kwa mwana wosabadwayo ndi kulemera kwake. Amayi akapitilira ndi lactoferrin Mlingo wa mkaka wa mkaka wa m'mawere, mayendedwe ake amkaka amapeza bwino. Kupatula apo, mwana amatha kudzitamandira mopanda malire mu colostrum kuti akhale ndi thupi labwino.

Makanda ndi Ana Aang'ono Omwe Siamaweretsedwa kapena Kusakaniza

Lactoferrin imathandizira kuti khanda likhale ndi chitetezo champhamvu chamthupi poteteza matumbo osalimba kuchokera ku ziwindi. Kuphatikiza apo, chowonjezeracho chimagwira ntchito ngati mankhwala othandizira, othandizira kuyenda koyambira kwa mwana. Ma formula achichepere olemera mu colostrum amapezeka kwa ogulitsa online ndi Lactoferrin ufa.

Kuperewera kwa Chitsulo

Lactoferrin yowonjezera imachulukitsa milingo ya hemoglobin, maselo ofiira am'magazi, ndi ferritin. Ngakhale anthu ambiri amagwiritsa ntchito ferrous sulfate kuthana ndi kuchepa kwa chitsulo, kafukufuku wambiri akutsimikizira kuti lactoferrin ndi wamphamvu kwambiri.

Ngati ndinu wamasamba kapena wopereka magazi pafupipafupi, mufunika zakudya zamafuta azitsulo kuti mupange hemoglobin wotsika komanso ferritin. Kupanda kutero, mutha kupanga lactoferrin yabwino kugula kuchokera kwa ogulitsa pa intaneti.

Anthu okhala ndi Low immune

Lactoferrin amateteza thupi ku tizilombo toyambitsa matenda mwa kutulutsa kachilombo koyambitsa matenda ndikulepheretsa kuchuluka kwa mabakiteriya ndi mavairasi. Pulogalamuyo imathandizira kusintha kosunthira ma signways omwe amayang'anira kuwunika kwa omwe akukhala nawo.

Lactoferrin amagwira ntchito ngati mkhalapakati, kutsata ndi kulumikizana ndi mgwirizano pakati pa zochita zamagulu olimbitsa thupi. Mwachitsanzo, imawongolera zochitika zapgocytic mwa kukweza kwa ma neutrophils ndi macrophages. Kwa chitetezo chamthupi chogwiritsa ntchito, panganoli limathandizira kusinthasintha kwa ma T-cell ndi ma B-cell, omwe amawonetsa chitetezo chamaselo komanso chazonda, chimodzimodzi.

8. Lactoferrin wokhala ndi IgG

Monga lactoferrin, IgG kapena immunoglobulin G ndi puloteni yotsutsa-tizilombo tating'onoting'ono tomwe timakhala m'mkaka wa mammary.

Kafukufuku angapo akupezeka kuti afotokoze kulumikizana pakati pa lactoferrin ndi IgG.

Kuchuluka kwa lactoferrin mu colostrum ndikwapamwamba kwambiri kuposa kumene kwa IgG. Malinga ndi asayansi ofufuza, zinthu zingapo zimakhudza kuchuluka kwa mapuloteni awa mkaka.

Mwachitsanzo, onse lactoferrin ndi IgG amamva kutentha ndi kutenthedwa. Immunoglobulin G imatha kuletsa kutentha kwa 100 ° C koma pang'ono masekondi. Mosiyana ndi izi, lactoferrin imatsika pang'onopang'ono ndi kuwonjezeka kwa kutentha mpaka kufota kwathunthu ku 100 ° C.

Polemba izi, muyenera kuti mwazindikira kuti nthawi ndi kutentha kwa kutentha ndizofunikira kwambiri pokonzekera mkaka wa neonatal. Popeza kuwotcha mkaka kwadzetsa mikangano, anthu ambiri amafunitsitsa kuti ziume.

Kuzunza kwa Lactoferrin (146897-68-9) ili pachimake pakabadwa. Nthawi yotsalira pambuyo pake ikachulukirachulukira, mapuloteni awa amayamba kuchepa, mwina chifukwa cha kuchepa kwa colostrum. Kumbali ina, kugwa kwa milingo ya immunoglobulin G pafupifupi kosafunikira nthawi yonse ya msambo.

Komabe, lactoferrin yambiri imatsikira mkaka wa mamalia, kuphatikiza kwake kumakhalabe kokulirapo kuposa kwa IGG. Izi zimayimirabe ngati mu colostrum, kusinthasintha, kapena mkaka okhwima.

Zothandizira

  • Yamauchi, K., et al. (2006). Bovine Lactoferrin: Zopindulitsa ndi Mechanism of Action motsutsana ndi matenda. Biochemistry ndi Cell Biology.
  • Jeffrey, KA, et al. (2009). Lactoferrin monga Wopanga Zoletsa Zachilengedwe. Kupanga Kwaposachedwa Mankhwala.
  • Lepanto, MS, et al. (2018). Kuchita bwino kwa Lactoferrin Oral Administration mu Chithandizo cha Anemia ndi Anemia of kutupa mu Amayi Oyembekezera komanso Opanda Pakati: Phunziro Lophatikizira. Malire a Immunology.
  • Goldsmith, SJ, et al. (1982). IgA, IgG, IgM ndi Lactoferrin Zamkati Wa Mkaka Waumunthu Pa Nthawi Yoyambira Kuwala Ndi Zovuta Zakuchita Ndikusungira. Zolemba Za Kutetezedwa Kwa Chakudya
  • Smith, KL, Conrad, HR, ndi Porter, RM (1971). Lactoferrin ndi IgG Immunoglobulins ochokera kwa Bovine Mammary Glands. Zolemba za Science Science.
  • Sanchez, L., Calvo, M., ndi Brock, JH (1992). Udindo Wachilengedwe wa Lactoferrin. Zolemba Zakale za Matenda Aunyamata.
  • Niaz, B., et al. (2019). Lactoferrin (LF): Mapuloteni Achilengedwe Oletsa Kupha Microbial. International Journal of Food Properties.