Kodi Oxiracetam ndi chiyani?

Oxiracetam ndi imodzi mwa nootropic yakale zowonjezera ochokera kubanja la racetam. Anali gulu lachitatu la racetam pambuyo pa piracetam ndi aniracetam ndipo idapangidwa koyamba m'ma 1970. Oxiracetam ndi mankhwala ochokera ku racetam yoyambirira, piracetam.

Monga ma racetams ena, oxiracetam imakhala ndi pyrrolidone pachimake pake. Komabe, oxiracetam ili ndi gulu la hydroxyl, ndichifukwa chake imakhala yamphamvu kwambiri kuposa kholo lawo, piracetam.

Imadziwika bwino chifukwa chokhoza kukonza magwiridwe antchito azidziwitso monga kukumbukira, kuyang'ana komanso kuphunzira komanso zotsatira zoyipa zomwe zimapereka. Oxiracetam nootropics imakulitsa thanzi lanu lonse laubongo.

Oxiracetam ufa: Kodi Oxiracetam Amagwiritsidwa Ntchito Motani?

Pali mitundu yambiri ya oxiracetam yomwe inanenedwa ndi ofufuza komanso zokumana nazo za oxiracetam zomwe zidagawana pamapulatifomu osiyanasiyana.

Oxiracetam, monga racetam ina iliyonse, imagwiritsidwa ntchito kupititsa patsogolo kuzindikira mwa kukonza kuthekera kopanga kukumbukira kwakanthawi kochepa komanso kwakanthawi. Chifukwa chake imagwiritsidwa ntchito ndi aliyense amene amafunika kuphunzira ndikukumbukira zambiri. Ndizabwino kwambiri kwa ophunzira omwe akuyenera kuchita bwino pamayeso awo, chifukwa zithandiza kwambiri kuphunzira ndikukumbukira zida mosavuta. Zimathandizanso kuti azingoganizira kwambiri ndikukhala ndi chidwi kwanthawi yayitali.

Ntchito ya Oxiracetam ndizapadera chifukwa zimapereka chidziwitso pakulimbikitsa malingaliro anu kuti mukhale ozindikira komanso atcheru. Chinthu chabwino kwambiri pazotsatira zake ndikuti mosiyana ndi zina zomwe zimapangitsa kuti munthu azikhala womangika komanso wosakhazikika, oxiracetam imalimbikitsa malingaliro ndikukusiyani bata ndi kumasuka. Kwa ogwira ntchito omwe amafunikiradi kusinkhasinkha ndikuwunika, zochitika za oxiracetam ndizosakayikitsa.

Kafukufuku akuwonetseranso kuti oxiracetam imagwiritsa ntchito pochiza kuchepa kwazindikiritso kuphatikiza kuchepa kwa kukumbukira kwa odwala omwe ali ndi matenda a Alzheimer powapatsa chitetezo cha neuronal.

Mwachitsanzo, wina akukonzekera kuyankhulana, zidzakhala zofunikira kuoneka anzeru. Oxiracetam imakweza bwino mawu omwe amathandiza anthu kugwiritsa ntchito mawu abwino omwe amalimbikitsa mwayi wawo wopeza ntchito zomwe amalota.

Oxiracetam ufa ndichonso njira ya kukumbukira kukumbukira okalamba omwe nthawi zambiri amakhala ndi vuto lokumbukira kapena kuchepa.

Popeza matupi athu samapanga oxiracetam mwa iwo okha, kuti mutenge phindu la oxiracetam mudzalingalira kuti oxiracetam imagula kwa ogulitsa odalirika. ?????

Kafukufuku wambiri waanthu adakhazikitsidwa ndi okalamba komanso anthu osakhala athanzi, chifukwa chake kafukufuku wambiri pa anthu athanzi angafunike kutsimikizira kugwiritsa ntchito oxiracetam. Komabe, kuwunika kwa oxiracetam kumawonetsa kuthekera kwa oxiracetam mwaumoyo komanso wachinyamata.

Oxiracetamu

Oxiracetam: Kodi imagwira ntchito bwanji?

Ngakhale, phindu la oxiracetam limadziwika bwino momwe magwiridwe antchito amagwirira ntchito sanatanthauziridwe bwino. Komabe, njira zingapo za oxiracetam zimanenedwa.

M'munsimu muli njira zina za oxiracetam;

i. Amayang'anira neurotransmitter, acetylcholine

Ma neurotransmitters awiriwa amatenga gawo lofunikira pakukwanitsa kwathu kupanga kukumbukira kwakanthawi kochepa komanso kwakanthawi, kuphunzira ndi magwiridwe antchito azidziwitso.

Oxiracetam imathandizira machitidwe a cholinergic ndi glutamate potero amasinthitsa kutulutsidwa kwa ma neurotransmitters ofunikira, acetylcholine ACh ndi glutamate.

Makamaka, oxiracetam imapangitsa chidwi cha ma acetylcholine receptors. Imachita izi popititsa patsogolo michere ya protein kinase C (PKC) yomwe imakhudza ma M1 acetylcholine receptors.

Oxiracetam nootropic imawonetsedwanso kuti imatha kukonzanso zolandilira zomwe zimawonetsetsa kuti ACh ikukhudzana ndi magwiridwe antchito.

ii. Zolimbikitsa za psycho

Oxiracetam nootropics imapereka mphamvu zolimbitsa pang'ono pakatikati mwa manjenje.

Oxiracetam imagwera m'mabanja ampakine azida. Ampakine amadziwika kuti amawonetsa zinthu zolimbikitsa. Ampakine ndi mankhwala omwe amathandizira ma glutamatergic AMPA receptors. Mwamwayi, mosiyana ndi zinthu zina zopatsa mphamvu monga caffeine yomwe imakulepheretsani kugona komanso kuchita mantha, ampakine samakusiyirani zovuta zilizonse.

Oxiracetam chifukwa chake imapereka zolimbikitsa zomwe zimakupangitsani kukhala tcheru ndikuwunika pomwe zikusiyirani malingaliro ndi thupi bata ndi kumasuka.

Kuphatikiza apo, oxiracetam imatha kukweza milingo yama phosphates amphamvu kwambiri omwe amathandizira kukulitsa mphamvu komanso kukulitsa chidwi.

iii. Sungani dongosolo la glutamate

Oxiracetam imakhudza dongosolo la glutamate ndipo imathandizira kutulutsa kwa neurotransmitter, glutamate. Imakhala ndi zotsatira zabwino komanso kwa nthawi yayitali.

Glutamate ndi imodzi mwama neurotransmitter ochuluka kwambiri mu dongosolo la neural lomwe nthawi zambiri limatumiza zizindikilo kuubongo ndi thupi lonse.

Glutamate amatenga gawo lofunikira pakugwira ntchito mozindikira komanso makamaka ndi kukumbukira komanso kuphunzira.

iv. Imathandizira kulumikizana pakati pa ma neuron

Kafukufuku wina akuwonetsa kuti oxiracetam imathandizira kulumikizana pakati pa ma neuron mu hippocampus. Hippocampus ndi gawo laubongo lomwe limakhudza kukumbukira, kutengeka, ndi mitsempha yapakati.

Oxiracetam amakwaniritsa izi m'njira ziwiri. Imodzi ndiyo kuyambitsa kutulutsidwa kwa D-aspartic acid ndipo chachiwiri, pokhudza kagayidwe kake ka lipid. Lipid metabolism kuonetsetsa kuti pali mphamvu zokwanira zamaganizidwe zofunika kuti ma neuron azigwira ntchito.

Zotsatira za Oxiracetam & Ubwino

Pali mitundu ingapo ya ma oxiracetam omwe amafotokozedwera ngakhale zowonjezerazo sizivomerezedwa ndi Food and Drug Administration (FDA).

M'munsimu muli oxiracetam amapindula;

i. Zimathandizira kukumbukira ndi kuphunzira

Oxiracetam ndiyotchuka kwambiri chifukwa chokhoza kukumbukira kukumbukira. Zimathandizira kupanga kukumbukira kwatsopano komanso kuwonjezera kuthamanga komwe malingaliro amakumbukira ndikukumbukira zambiri.

Oxiracetam imathandizanso kukumbukira kukumbukira pochepetsa kuwonongeka kwa minyewa, kutulutsa kagayidwe kabwino ka lipid muubongo, kuwonjezeka kwa magazi komanso kuletsa kuyambitsa kwa astrocyte.

Kutuluka kwa magazi m'dera lam'mimba ndikofunikira kwambiri kuti mpweya wabwino ufike kuubongo kuti ubongo uzigwira bwino ntchito kuphatikiza kukumbukira.

Kuphatikiza apo, kupsyinjika kwa oxidative kumatha kuchitika pazifukwa zingapo ndipo ngati kusalamulirika kumatha kuwonongeka ndi ma neuronal. Zowonjezera za Oxiracetam athandizireni pakuchepetsa kuwonongeka kwa ma neuron.

Kuphatikiza apo, oxiracetam akuti imathandizira kusintha kwa nthawi yayitali mwina chifukwa chowonjezera kutulutsa kwa glutamate ndi-aspartic acid mu hippocampus.

Pofufuza anthu okalamba 60 omwe ali ndi kuchepa kwazindikiritso, kuchuluka kwa oxiracetam kwa 400 mg katatu tsiku lililonse kumapezeka kuti kumathandizira kukumbukira ndikuchepetsa zizindikiritso zakuchepa kwachidziwitso.

Pakafukufuku wina wa anthu okalamba 40 omwe ali ndi vuto la misala, oxiracetam pa 2,400 mg tsiku lililonse amapezeka kuti amasintha kwakanthawi chikumbukiro komanso kulankhula momasuka.

ii. Imalimbitsa chidwi ndi chidwi

Mukakumana ndi ntchito yomwe imafunikira chidwi kwa nthawi yayitali, oxiracetam ikhoza kukhala chisankho chabwino. Moyo wa Oxiracetam uli pafupi ma 8-10 maola chifukwa chake imatha kupindulitsa nthawi yayitali.

Oxiracetam imatha kukuthandizani kuti muziyang'ana kwambiri ntchito nthawi yayitali osataya chidwi. Oxiracetam ndiyokhudzana ndi kupanga mphamvu muubongo motero kumapereka mphamvu yofunikira kuti athe kuyang'ana kwambiri pantchito kwakanthawi komanso kuphunzira zinthu zatsopano mosavuta.

Oxiracetam imapereka zofatsa zomwe zimakuthandizani kuti muziyang'ana popanda kutaya chidwi kapena chidwi.

M'mayeso awiri amunthu okhudzana ndi okalamba 96 omwe ali ndi matenda a dementia ndipo inayo imakhudza anthu 43 omwe ali ndi kuchepa kwanzeru, oxiracetam supplementation idapezeka kuti ikuthandizira nthawi yoyankhira komanso chidwi.

Oxiracetamu

iii. Zotsatira zoyipa

Oxiracetam supplement amakhala ndi ma neuroprotective phindu chifukwa amatha kuteteza mawonekedwe a ubongo ndikuwonongeka kwazidziwitso chifukwa cha msinkhu kapena kuvulala kwaubongo.

Oxiracetam imatha kuteteza ubongo ku zipsinjo zomwe zimayambitsa matenda a Alzheimer's komanso matenda ena a dementia.

Kafukufuku wambiri wazinyama akuwonetsa kuti oxiracetam imatha kuteteza ubongo kuti usawonongeke. Mwachitsanzo, mu kafukufuku yemwe ma neurotoxins adayambitsidwa kuti asokoneze kukumbukira kukumbukira ngati kuvulala kwaubongo, chithandizo chisanafike ndi oxiracetam chidapezeka kuti chiteteze neurotoxicity.

Kafukufuku wowonjezera wavumbula kuti, mankhwala a oxiracetam atatha kuteteza makoswe ku sitiroko yoletsa kuthana ndi zotchinga zamaubongo am'magazi.

Pakafukufuku waumunthu wa odwala 140 omwe adadwala stroko chifukwa cha kuthamanga kwa magazi (oopsa), oxiracetam idaperekedwa limodzi nerve kukula factor (NGF). Mankhwalawa anapezeka kuti athandiza ubongo kuchira komanso kuwonjezera kupulumuka. Kafukufukuyu adanenanso kuchepetsa kutupa komanso kulimbitsa mphamvu zamtundu womwe ndizizindikiro zakubwezeretsa pambuyo pakuwonongeka kwa ubongo.

iv. Kupititsa patsogolo kuzindikira kwakumverera

Oxiracetam imakhudza momwe timazindikira zinthu kudzera mu mphamvu zisanu za kuwona, kununkhiza, kukhudza, kumva komanso ngakhale kulawa.

Mukatenga oxiracetam imachulukitsa magazi omwe amatulutsa malingaliro omwe amathandizira malingaliro kuzindikira ndi kukonza komanso kutanthauzira zomwe timazindikira.

Kuzindikira kwamalingaliro kumatanthawuza kupanga zisankho zabwino modekha.

v. Bwino mawu

Oxiracetam imawonetsedwa kuti imathandizira kugwira ntchito kwa ubongo ndipo imatha kusintha bwino mawu. Kulankhula bwino ndi chimodzi mwazinthu zanzeru zomwe zimatithandiza kuti tipeze zomwe takumbukira.

Pakafukufuku wa anthu 73 omwe ali ndi vuto la dementia (MID) kapena ma dementia oyambilira (PDD), oxiracetam idapezeka kuti iteteza kuchepa kwa chidziwitso komanso idawongolera bwino mawu awo.

vi. Kuchulukitsa kukhala tcheru

Kukhala maso ndi kuyang'ana ndikofunikira kuti mugwire bwino ntchito. Oxiracetam imapereka zofatsa zomwe zimakuthandizani kuti mukhale ogalamuka pakuwonjezera magazi muubongo.

Pakafukufuku wa anthu 289 omwe ali ndi vuto la misala, oxiracetam idapezeka kuti ikuthandizira kuzindikira. Adanenanso kuti amalimbikitsa kukhala tcheru pomwe amachepetsa nkhawa komanso mantha.

Ufa wa Oxiracetam: Mlingowu uti?

Kutengera kuyesedwa kwamankhwala mtundu woyenera wa oxiracetam ndi 750-1,500 mg patsiku. Mlingo wa oxiracetam umagawika m'magulu awiri omwe amatengedwa m'mawa ndi m'mawa.

Muyenera kupewa kutenga oxiracetam supplement madzulo chifukwa imakhala ndi zovuta zomwe zingasokoneze kugona kwanu.

Popeza oxiracetam imasungunuka m'madzi imatha kumwedwa ngati piritsi, kapisozi kapenanso ufa, ngakhale wopanda chakudya.

Kafukufuku akuwonetsa kuti oxiracetam imatenga pafupifupi maola 1-3 kuti ifike pachimake mu seramu ndipo chifukwa chake iyenera kutengedwa ola limodzi isanachitike ntchito yophunzirira. Moyo wa oxiracetam uli pafupifupi maola 8-10 ndipo muyenera kuyembekezera kufikira kumapeto kwa sabata limodzi.

Ngakhale, kafukufuku wina wagwiritsa ntchito milingo yayikulu ya oxiracetam mpaka 2,400 mg tsiku lililonse, nthawi zonse kuyambira pazoyambira zotsika kwambiri kupita mtsogolo momwe zingafunikire.

Kuphatikiza apo, popeza oxiracetam imathandizira kuti acetylcholine ichite bwino muubongo, onetsetsani kuti mukuyikapo ndi gwero labwino la choline monga Alpha GPC kapena CDP choline. Izi zidzakuthandizani kupewa zotsatira zoyipa za oxiracetam makamaka kupweteka kwa mutu chifukwa chosakwanira choline muubongo.

Zotsatira za Oxiracetam

Oxracetam nootropic amadziwika kuti ndi yotetezeka komanso imalekerera thupi.

Komabe, zovuta zina za oxiracetam zomwe zanenedwa ndi monga;

Mutu - izi zimachitika pamene wina amaiwala kusunga oxiracetam ndi gwero labwino la choline. Mutu umachitika chifukwa chosakwanira choline muubongo. Izi zitha kupewedwa potenga oxiracetam stack yokhala ndi choline monga Alpha GPC.

Kusowa tulo komanso kupumula ndizovuta kwambiri za oxiracetam. Amanenedwa ngati wina amamwa kwambiri oxiracetam kapena kumwa mankhwalawo madzulo. Pofuna kuthana ndi zotsatirazi za oxiracetam, nthawi zonse tengani mlingo woyenera ndikukhala ndi chizolowezi chotenga oxiracetam masana masana kuti musasokonezeke.

Zina mwazovuta za oxiracetam ndizo;

  • mseru,
  • Matenda oopsa,
  • Kutsekula m'mimba kapena kudzimbidwa, ndi

Oxiracetamu

Malangizo Okhazikika a Oxiracetam

Mafuta a Oxiracetam amagwira ntchito bwino kwambiri kuti apititse patsogolo kuzindikira ndi kuyambitsa dongosolo lamanjenje lokhalo kapena kuphatikiza ndi zowonjezera zina.

-oxiracetam Alpha GPC okwana

Monga ma racetams ena, Oxiracetam okwanira ndi choline gwero ndikofunikira kwambiri. Kuyika ndi Alpha GPC sikuti kumangowonjezera zotsatira zake komanso kumathandizanso kupewa kupezeka kwa mutu komwe kumakhudzana kwambiri ndi kuchepa kwa choline muubongo.

Mlingo wa oxiracetam alpha GPC umakhala 750 mg wa oxiracetam ndi 150-300 mg wa Alpha GPC wotengedwa m'miyeso iwiri, m'mawa ndi masana.

-oxiracetam noopept okwana

Noopept ndi imodzi mwama nootropics abwino kwambiri omwe amadziwika kuti amathandizira kuzindikira kwathunthu ndipo imagwira ntchito mofanana kwambiri ndi ma racetams.

Mukayika oxiracetam ndi noopeptMukuyembekeza kukumana ndi magwiridwe antchito anzeru kuphatikiza, chikumbukiro, kuphunzira, kukhala tcheru, kulimbikitsa komanso kuwunika.

Mlingo woyenera wa katunduyu ungakhale 750 mg wa oxiracetam ndi 10-30 mg wa noopept, wotengedwa tsiku lililonse.

-unifiram oxiracetam okwana

Unifiram ndi gulu la nootropic lomwe limatengedwa kuti lithandizire kuzindikira komanso momwe mapangidwe ake amafanana ndi ma racetams. Komabe, mayesero azachipatala akusowa ndipo izi zimapangitsa kuti zikhale zovuta kunena zomwe zingagwirizane nazo.

Komanso, chifukwa imagwiranso ntchito mofananamo, ma unifiram omwe amakhala ndi ma racetams kuphatikiza oxiracetam atha kuchititsa chidwi chazotheka. Amawonetsedwa kuti ndiopambana kuposa ma racetams motero chifukwa chotsika kwambiri chidzafunika kukwaniritsa zotsatirazi.

Kutengera unifiram ndi oxiracetam zomwe zimakumana ndi mlingowo ziyenera kukhala 5-10 mg ya unifiram ndi 750 mg ya oxiracetam yotengedwa tsiku lililonse.

-Oxiracetam ndi Pramiracetam okwana

Oxiracetam imakhala bwino kwambiri pamipikisano ina.

Mukamagwiritsa ntchito oxiracetam stack ndi pramiracetam, kuzindikira kwa kukumbukira, kuganizira ndi kulimbikitsa kumalimbikitsidwa komanso kuti zokolola zanu ziwonjezeke.

Mphamvu yofatsa ya oxiracetam imathandizanso kukulitsa chidwi ndi kusinkhasinkha chifukwa chakulimbitsa mphamvu zamaganizidwe.

Mlingo woyenera wa katunduyu ndi 750 mg wa oxiracetam ndi 300 mg wa pramiracetam womwe umatengedwa kamodzi tsiku lililonse. Oxiracetam imatha kutengedwa pamimba yopanda kanthu popeza imasungunuka madzi pomwe pramiracetam imatha kuphatikizidwa pachakudya choyamba popeza ndi mafuta osungunuka osungunuka.

Komwe mungagule oxiracetam

Oxiracetam nootropic imapezeka mosavuta pa intaneti. Ngati muganiza kutenga oxiracetam mugule kwa ogulitsa otchuka kwambiri a nootropic pa intaneti. Ganizirani kuti muphunzire mosamala za oxiracetam ufa, makapisozi kapena mawonekedwe apiritsi omwe amaperekedwa.

Kuyang'ana zokumana nazo za oxiracetam zomwe zimagawidwa patsamba la kampani ndi njira imodzi yotsimikizirira kuti mwapeza zomwe mukuyang'ana.

Ndemanga za Oxiracetam patsamba la ogulitsa ndikutsegulira maso kwa oxiracetam nootropics yabwino chifukwa si onse omwe amapereka zinthu zabwino kwambiri.

Zothandizira
  1. Dysken, MW, Katz, R., Stallone, F., & Kuskowski, M. (1989). Oxiracetam pochiza matenda am'magazi am'magazi am'magazi am'magazi am'magazi am'magazi am'magazi ambiri. Journal of neuropsychiatry ndi ma neuroscience azachipatala, 1(3), 249-252.
  2. Hlinák Z, Krejcí I. (2005). Oxiracetam pre- koma osalandira chithandizo chamankhwala amalepheretsa kuchepa kwazomwe anthu amapanga ndi trimethyltin mu makoswe. Behav Brain Res.
  3. Huang L, Shang E, Fan W, Li X, Li B, Iye S, Fu Y, Zhang Y, Li Y, Fang W. (2017). S-oxiracetam amateteza ku ischemic stroke kudzera pochepetsa magazi kutchinga kosagwira makoswe.Eur J Pharm Sci.
  4. Maina, G., Fiori, L., Torta, R., Fagiani, MB, Ravizza, L., Bonavita, E., Ghiazza, B., Teruzzi, F., Zagnoni, PG, & Ferrario, E. (1989). ). Oxiracetam pochiza matenda opatsirana oyamba ndi opatsirana pogonana: kafukufuku wamaso awiri, wakhungu. Neuropsychobiology, 21(3), 141-145.
  5. Rozzini R, Zanetti O, Bianchetti A. (1992). Kuchita bwino kwa mankhwala a oxiracetam pochiza zofooka zam'maganizo pambuyo pa kuwonongeka kwakukulu kwa dementia. Accta Neurol (Napoli).
  6. Dzuwa, Y., Xu, B., & Zhang, Q. (2018). Kukula kwamitsempha kuphatikiza ndi Oxiracetam pochiza Hypertensive Cerebral Hemorrhage. Nkhani yaku Pakistan ya sayansi yamankhwala, 34(1), 73-77.

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