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Mafuta a Caffeic acid (phenethyl ester powder) (104594-70-9)

(1 kasitomala review)

Mafuta akuluakulu a caffeic acid ndi phenethyl ester ufa ndi phenethyl alcohol ester ya caffeic acid ndi bioactive ......


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum
mphamvu: 1180kg / mwezi

Kufotokozera

Mafuta a Caffeic acid a phenethyl ester powder (104594-70-9) kanema

Mafuta a Caffeic acid (phenethyl ester powder) (104594-70-9) Szizindikiro

Name mankhwala Yaikulu Caffeic acid asidi phenethyl ester ufa
Mankhwala Name Mafuta akuluakulu a Caffeic acid; phenethyl ester ufa;

Caffeate ya Phenylethyl; Phenethyl caffeate; Caffeic acid 2-phenylethyl ester; caffeate ya β-phenylethyl;

2-Phenylethyl (2E) -3- (3,4-dihydroxyphenyl) acrylate

Brand NAme Palibe deta yopezeka
Kalasi ya Mankhwala Tyrosine Kinase Inhibitors, Inhibitors
Nambala ya CAS 104594-70-9
InChIKey SWUARLUWKZWEBQ-VQHVLOKHSA-N
Maselo Fmphutsi C17H16O4
Maselo Wasanu ndi atatu 284.311 g / mol
Misa ya Monoisotopic 284.31 g · mol-1
Kusungunula Pmafuta 125-126ºC (dec.)
Malo otentha 498.6 ± 45.0 ° C pa 760 mmHg
Halimo Half-Life Palibe Dongosolo Lilipo
mtundu kuchoka poyera
Szovuta Sungunulani mu ethyl acetate pa 50mg / ml. Kusungunuka mu DMSO ndi ethanol.
Smazunzo Tkutentha Sungani ku 0 ° C
Yaikulu ya Caffeic acid acid phenethyl ester ufa Amalingaliro Cytotoxic wothandizira matenda a khansa. Inhibitor of ornithine decarboxylase ndi mapuloteni tyrosine kinase. Inapezeka kuti ndi inhibitor yeniyeni ya nyukiliya, NF-kB. Kuwonetseranso kuti kulimbikitsa kwambiri lipoxygenase njira ya arachidonic asidi metabolism panthawi yotupa.

Mafuta a Caffeic acid (phenethyl ester powder) (104594-70-9)

Mafuta akuluakulu a Caffeic acid ndi phenethyl ester ufa ndi phenethyl alcohol ester ya caffeic acid ndi chigawo chokhazikika cha chisa cha mng'oma, ndi mankhwala osokoneza bongo, maselo a cytoprotective ndi immunomodulating. Pakulamulira, Raw Caffeic acid (phenethyl ester powder) (CAPE) imaletsa NF-kappa B kukonza nyukiliya ndipo imatha kuletsa p70S6K ndi njira zozindikiritsira Akt. Kuonjezera apo, CAPE imaletsa PDGF kuwonjezereka kwa maselo osakanikirana a maselo kudzera pulojekiti ya p38 yomwe imayambitsa mapuloteni kinase (MAPK) ndi hypoxia-inducible factor (HIF) -1alpha komanso kudulidwa kwa heme oxygenase-1 (HO-1) .

Caffeic acid amachititsa kuti phenethyl ester ikhale ndi anti-carcinogenic, anti-inflammatory, ndi immunomodulatory properties. CAPE imaletsanso HIV-1 integrase. Zizindikiro zotsutsana ndi zotupa zimaganiziridwa kuti ndizo chifukwa cha kuchotsa lipoxygenase njira ya arachidonic acid metabolism ndi CAPE. Zofukufuku zawonetsanso kuti CAPE ndiyoyikitsa komanso yothetsa mphamvu ya NF kappa B, yomwe imakhala ndi mapuloteni omwe amachititsa kuti DNA ilembedwe. Caffeic Acid Phenethylester ndi choletsa cha ODC ndi Tyrosine Kinase

Caffeic acid acid phenethyl ester powder (104594-70-9) Njira yogwira ntchito

Mankhwala a caffeic acid phenethyl ester ndi omwe amapanga ming'oma ya uchi, amachititsa kuti NF-κB iwonongeke chifukwa cha phorbol ester, ceramide, okadaic acid, ndi hydrogen peroxide poteteza kusintha kwa p65 subunit ya NF-κB kukati. Mu mitsempha yambiri yamagazi, Caffeic acid ya phenethyl ester imasonyeza ntchito yodalirika yotsutsana ndi EC50 ya 1.76, 3.16, 13.7, ndi 44.0 μM motsutsana ndi murine colon 26-L5, B16-BL6 melanoma, HT-1080 fibrosarcoma ndi mapapo a anthu A549 maselo a adenocarcinoma, motsatira. Caffeic acid, phenethyl ester, monga antioxidant yamphamvu, imakhala ndi anti-apoptotic mumaselo a cerebellar granule mwa kulepheretsa kupanga mapangidwe a ROS ndi kuletsa ntchito ya caspase. Komanso, Caffeic acid phosethyl ester imateteza kuti pulogalamu yopweteka kwambiri ya LPS, yomwe imayambitsa HSC, iwonongeke kwambiri, ndipo kuchititsa kuti LPS iwalimbikitse ku HSC kwa zizindikiro za fibrogenic pogwiritsa ntchito zizindikiro za NF-κB.

Mavitamini a Caffeic acid phenethyl ester (10 mg / kg, ip) amaletsa kukula ndi angiogenesis ya matumbo oyambirira mu C57BL / 6 ndi BALB / c mbewa zomwe zimayambitsidwa ndi Lewis lung carcinoma, colon carcinoma, ndi maselo a melanoma. Caffeic acid pulothyl ester (5, 10, 20 mg / kg) imasonyezanso zotsatira zolimbitsa thupi m'thupi mwa kuchepetsa kupweteka kwa thymus ndi / kapena maselo a thymus ndi ntchentche.

Kugwiritsa ntchito ufa wa Caffeic acid phenethyl ester (104594-70-9)

▪ Kuteteza thupi

▪ Zomwe sizikuwotcha

▪ Iimmunomodulator

▪ Blocker ya NFkB

ubwino Caffeic acid acid phenethyl ester ufa (104594-70-9)

Phenethyl caffeate ndi kampani yomwe imapezeka mu propolis, osakaniza ndi njuchi. Caffeic acid (phenomhyl ester) (CAPE) ikhoza kukhala yothandiza popewera ndi kuchiza matenda opweteka monga nyamakazi ya nyamakazi, njira zamakono za lupus ndi psoriasis, khansa zosiyanasiyana ndi matenda omwe ali ndi vuto lopweteketsa, matenda a cataracts, ndi matenda ena omwe amayamba chifukwa cha kupanikizika kwa magazi. Kuwonjezera apo, CAPE ikhoza kugwiritsidwa ntchito pochiza kachilombo ka HIV mukakhala pamodzi ndi mankhwala omwe ali ndi kachilombo ka HIV. Ikhozanso kugwiritsidwa ntchito kutsutsana ndi atherosclerotic, antioxidative, cardioprotective, anti-obesity ndi antimitogenic.


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1 review kwa Mafuta a Caffeic acid (phenethyl ester powder) (104594-70-9)

  1. Phcoker -

    Ali ndi Caffeic acid phosethyl ester powder kuti ayesedwe, zotsatira zowonetsera zimasonyeza bwino kwambiri ndi chiyero!

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