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Mpweya wa Nicotinamide Mononucleotide (NMN) wakuda (1094-61-7)

(1 kasitomala review)

Nkhumba yaikuru ya Nicotinamide Mononucleotide (NMN) yomwe inalepheretsa kulemera kwa thupi kwa zaka zapitazo ......


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum
mphamvu: 1370kg / mwezi

Kufotokozera

Pulogalamu yapamwamba ya Nicotinamide Mononucleotide (NMN) (1094-61-7) kanema

Mphungu ya Nicotinamide Mononucleotide (NMN) powder (1094-61-7) Ndemanga

Nkhumba ya Nicotinamide Mononucleotide powder ("NMN" ndi "β-NMN") ndi nucleotide yotengedwa kuchokera ku ribose ndi nicotinamide. Mofanana ndi nicotinamide riboside, NMN ndizochokera ku niacin, ndipo anthu ali ndi michere yomwe ingagwiritse ntchito NMN kupanga nicotinamide adenine dinucleotide (NADH).

Chifukwa chakuti NADH ndi cofactor yothandizira mkati mwa mitochondria, chifukwa siritini, ndi PARP, NMN yaphunzitsidwa ndi zinyama monga chodziwitsira chisokonezo komanso anti-aging agent. Makampani othandizira zakudya adayambitsa malonda a NMN malonda omwe amawauza kuti apindule nawo, ngakhale kuti palibe maphunziro a zachipatala omwe anthu amafalitsidwa.

Mphungu ya Nicotinamide Mononucleotide (NMN) powder (1094-61-7)

Name mankhwala Mphungu yaikulu ya Nicotinamide Mononucleotide (NMN)
Mankhwala Name Beta-nicotinamide ribose monophosphate; Nkhumba ya Nicotinamide Mononucleotide powder; AC1Q6RVF; AC1L23AN; NMN (+); SCHEMBL6858129
Brand NAme Mirailabo
Kalasi ya Mankhwala Zakudya zowonjezera
Nambala ya CAS 1094-61-7
InChIKey DAYLJWODMCOQEW-TURQNECASA-N
Maselo Fmphutsi C11H15N2O8P
Maselo Wasanu ndi atatu 334.22
Misa ya Monoisotopic 335.229 g / mol
Kusungunula Pmafuta > 96 ° C
Fkubwezeretsanso Pmafuta Palibe tsiku likupezeka
Halimo Half-Life Choncho, monga momwe tawonetsera mkuyu: 3, nicotinamide inatheratu mwazi ndi theka la maola a 5.3, pamene theka la moyo wa nicotinic asidi inali ola la 1.1.
mtundu Yoyera mpaka wofiira
Szovuta Methanol (Pang'ono), Madzi (Pang'onopang'ono)
Smazunzo Tkutentha Zosakaniza, -20˚C Freezer, pansi pa malo osadziwika
Amalingaliro Pofuna kugwira ntchito yowonjezera moyo ndikuchiza matenda a shuga

Nkhono ya Nicotinamide Mononucleotide (NMN) ufa (1094-61-7) Ndemanga

Nkhumba ya Nicotinamide Mononucleotide powder ("NMN" ndi "β-NMN") ndi nucleotide yotengedwa kuchokera ku ribose ndi nicotinamide. Mofanana ndi nicotinamide riboside, NMN ndi chiyambi cha niacin, ndipo anthu ali ndi michere yomwe ingagwiritse ntchito NMN kupanga nicotinamide adenine dinucleotide (NADH).

Kafukufuku watsopano akusonyeza kuti NMN ikhoza kubwezeretsa kagayidwe ka maselo, ndikukhala ndi zotsatira zotsutsa kwambiri. Pochita mwachibadwa m'thupi, NMN (β-Nicotinamide mononucleotide) ndi yofunika kwambiri kuti kutembenuka kwa zakudya kukhale mphamvu. Kuwonjezera NMN monga gawo la ulamuliro wanu wa tsiku ndi tsiku kungapereke mphamvu zowonjezera mphamvu, kutetezera ku ukalamba, ndi kuchepetsa chiopsezo cha mavuto a mtima. NMN ndi cofactor mu redox, chochitika chofunika kwambiri kagwiritsidwe ntchito ka kagayidwe kake mu mapangidwe a ATP mphamvu yopereka mphamvu ya molecule. NMN ili ndi mankhwala omwe amachititsa kuti tizilombo toyambitsa matenda tiziyenda bwino.

Kugwiritsira ntchito Nicotinamide Mononucleotide (NMN) ufa (1094-61-7)

  1. Nicotinamide mononucleotide m'maselo aumunthu amagwira ntchito yofunika kwambiri mu mphamvu yowonjezera mphamvu, imaphatikizapo ku NAD yophatikizapo (nicotinamide adenine dinucleotide, mphamvu yamagetsi yotembenuka mtima yofunika coenzyme) kaphatikizidwe, yogwiritsidwa ntchito poletsa kukalamba, kugwa shuga ndi magazi ena.
  2. Nicotinamide Mononucleotide ndi vitamini wosasungunuka ndi madzi, Chomeracho ndi choyera chopanda mafuta, chosasunthika kapena chosavuta, chowawa kwambiri, chosungunuka mwa madzi kapena ethanol, chosungunuka mu glycerin.
  3. Nicotinamide Mononucleotidepowderis imakhala yosavuta kumamwa pamlomo, ndipo imafalitsidwa kwambiri m'thupi, ma metabolites owonjezera kapena mafano amachotsa mkodzo. Nicotinamide ndi mbali ya coenzyme I ndi coenzyme II yomwe imathandiza kuti hydrogen ikhale yopangidwa ndi okosijeni yopuma, imathandizira kuti tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda tizilombo toyambitsa matenda, tizilombo toyambitsa matenda (makamaka khungu, kapangidwe kakang'ono ndi mantha).

Kuonjezera apo, nicotinamide ili ndi chitetezo ndi chithandizo cha matenda a mtima, sinus node function ndi anti-fast experimental arrhythmias, nicotinamide ikhoza kusintha kwambiri kuthamanga mtima ndi atrioventricular block chifukwa cha verapamil.

ubwino ya Nicotinamide Mononucleotide (NMN) ufa (1094-61-7)

  • NMN Imalimbitsa Mphamvu ya Metabolism - NAD + imathandiza kuwononga chakudya monga shuga mu mphamvu.
  • Kumalimbikitsa ubongo wathanzi ndi ntchito ya mtima.
  • DNA Yothetsera Matenda Okalamba - NAD + imagwiritsidwa ntchito kukonza nsalu zosweka za DNA.
  • SIRTUIN Activator - NAD + imafunika kuti majini athu azitha kugwira ntchito.
  • NMN ndi COMPY yomwe amagwiritsidwa ntchito ndi Harvard Asayansi kuti ayimbenso zizindikiro zina za minofu yakale mu mbewa zomwe zinayamba kuthamangira ku NAD zowonjezereka.
  • Kuchiza kwa NMN kumateteza kuvulazidwa koopsa kwa ubongo
  • Mankhwala a NMN Amapulumutsa kuvutika kwa maganizo
  • Nicotinamide mononucleotide imalepheretsa JNK kukhazikitsa kuti asinthe matenda a Alzheimer
  • NMN ikhoza kubwezeretsa kuzindikira mu makoswe a AD

Analimbikitsa Nicotinamide Mononucleotide (NMN) ufa (1094-61-7) Mlingo

Mlingo wochuluka wa Nicotinamide Mononucleotide ufa uli palipakati pakati pa 250 - 1500 mg pa tsiku.

NMN imathamanga mofulumira kwambiri ndipo ili ndi hafu yaifupi, kotero kuti zisungidwe za NAD + zikhale zapadera tsiku lililonse momwe zingathere zimalimbikitsa kutenga kapu imodzi ya 125 mg pakuka ndi wina madzulo ngati mutenga 250 mg tsiku.

Zotsatira zoyipa ya Nicotinamide Mononucleotide (NMN) ufa (1094-61-7)

Ngakhale Nicotinamide mononucleotide (NMN) powder ndiwowonjezera watsopano ndipo kafukufuku akupitirira, maphunziro omwe apangidwa mpaka pano asonyeza kuti ali otetezeka komanso osakhala poizoni.

Zotsatira zake sizodziwika, koma kunjenjemera, chizunguliro, thukuta, ndi kunyoza kwakhala kwatchulidwa nthawi zina.


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Mafotokozedwe ndi zolemba zamagulu

2019 Mankhwala Otsutsa Otsutsa Okalamba: Nicotinamide Mononucleotide (NMN)

Zothandizira

  1. Mphero, KF, Yoshino, J., Yoshida, S., et al. (2016). Kulamulira kwa Nthaŵi Zakale za Nicotinamide Mononucleotide Zimasintha Mitengo ya Kusagwirizana Kwambiri M'magulu. Cell Metabolism.
  2. Yoshino, J., Mills, KF, Imai, SI, ndi Yoon, MJ (2011). Nicotinamide Mononucleotide, chofunika kwambiri cha NAD + Chokhazikika, Amachiza Pathophysiology Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chakudya Chamakono Cell Metabolism.
  3. Yamamoto, T., Byun, J., Zhai P., Ikeda, Y., Oka, S., ndi Sadoshima, J. (2014). Nicotinamide Mononucleotide, Wopakatikati wa NAD + Synthesis, Amateteza Mtima ku Ischemia ndi Reperfusion.
  4. Sinclair, DA, Uddin, GM, Youngson, NA, ndi Morris, MJ (2016). Mutu kupita ku Mutu Kufanizitsa Chithandizo cha Nthawi Yachidule ndi Chotsutsa NAD + Chotsatira Nicotinamide Mononucleotide (NMN) ndi Ma sabata asanu ndi limodzi a Kuchita Zozizira M'magulu Okazi Amuna.
  5. Imai, S., Yoshino, J., Mills, KF, Grozio, A., et al. (2019) Slc12a8 ndi Nicotinamide Mononucleotide Transporter. Chilengedwe cha Metabolism.
  6. De Picciotto, NE, Mills, KF, Imai, S., Gano, LB, et al. (2016). Nicotinamide Mononucleotide Amatsitsimutsa Matenda Osavuta ndi Mavuto Osokoneza Bongo ndi Amphawi Okalamba.
  7. Yao, Z., Gao, Z., Yang, W., ndi Jia, P. (2017). Nicotinamide Mononucleotide Imaletsa JNK Kukonzekera Kuti Muthane ndi Matenda a Alzheimer.
  8. Hou, Y., Wang, Y., Zhang, Y., Lautrup, S., et al. (2018). NAD + Zowonjezeretsa Zomwe Zimapangitsa Makhalidwe Aakulu a Alzheimer ndi DNA Kuwonongeka Mayankho mu New AD Mouse Model ndi Kutulutsidwa DNA Kukonza Kufooka.

1 review kwa Mpweya wa Nicotinamide Mononucleotide (NMN) wakuda (1094-61-7)

  1. boma -

    Ali ndi Nicotinamide Mononucleotide powder kuti ayesedwe, zotsatira zowonetsera zimasonyeza kwambiri khalidwe labwino ndi chiyero!

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