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NADH 2Na (606-68-8)

NADH ndi mtundu wa nicotinamide adenine dinucleotide (NAD) enzyme yogwira popanga ndi vitamini B3 ……….


Chikhalidwe: Mu Kupanga Misa
Zokonzedwa ndi Zokonzedweratu Zopezeka
mphamvu: 1277kg / mwezi

Kufotokozera

Zambiri za Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na)

Name mankhwala Beta-Nicotinamide adenine dinucleotide disodium mchere (NADH 2Na)
Mankhwala Name NADH (mchere wa disodium); Disodium nicotinamide adenine dinucleotide; eta-d-ribofuranosyl-3-pyridinecarboxamide, disodiumsalt; beta-NADH Disodium salt; Nicotinamide adenine dinucleotide, yafupika;
Nambala ya CAS 606-68-8
InChIKey QRGNQKGQENGQSE-WUEGHLCSSA-L
MUZIKONDWERETSA C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O.[Na+].[Na+]
Molecular Formula C21H27N7Na2O14P2
Kulemera kwa maselo 709.4
Misa ya Monoisotopic 709.088661 g / mol
Melting Point 140-142 ℃
mtundu Yellow
Stempage temp 2-8 ℃
Kutupa H2O: 50 mg / mL, momveka bwino, wachikasu
ntchito Mankhwala; zakudya ndi zakudya zopatsa thanzi;

Kodi Beta-Nicotinamide adenine dinucleotide disodium salt (NADH 2Na) ndi chiyani?

NADH ndi mtundu wa nicotinamide adenine dinucleotide (NAD), fomu yogwira ya coenzyme ya pawiri ndi vitamini B3. NADH (b-Nicotinamide adenine dinucleotide) Disodium Chumwa, yochepetsedwa, yomwe imadziwikanso kuti Nikotinamide adenine dinucleotide, ndi coenzyme mumayendedwe a redox. Ntchito zake monga kukonzanso wopereka ma elekitirodi munjira za catabolic kuphatikiza glycolysis, β-oxidation ndi citric acid mzunguko (Krebs mzunguko, TCA mzunguko). Mchere wa NADH disodium umatenganso zochitika zosonyeza maselo, mwachitsanzo ngati gawo lapansi la ma polymerases a poly (ADP-ribose) (PARPs) pa nthawi ya mayankho a kuwonongeka kwa DNA. Monga mchere wa disodium wa NADH, umagwiritsidwa ntchito pakudya ndi zakudya zowonjezera pothandizira matenda a Parkinson, matenda a kutopa kwambiri, matenda a Alzheimer's ndi matenda amtima.

Beta-Nicotinamide adenine dinucleotide disodium mchere (NADH 2Na) maubwino

Monga coenzyme ya oxidoreductases, mchere wa NADH disodium umagwira gawo lofunikira pakupanga mphamvu ya thupi.

- NADH disodium mchere ungapangitse kumvetsetsa bwino kwamaganizidwe, kukhala tcheru, kuganizira, komanso kukumbukira. Zitha kukulitsa chidwi cha m'maganizo ndipo zimatha kukulitsa chisangalalo. Itha kuwonjezera kuchuluka kwa mphamvu m'thupi ndi kukonza kagayidwe, mphamvu ya ubongo ndi kupirira.

- Thandizani anthu omwe ali ndi nkhawa yachipatala, kuthamanga kwa magazi kapena cholesterol yayikulu;

- Sinthani masewera;

- Kuchepetsa kukalamba ndikusunga umphumphu wa maselo amitsempha kuti athandizire dongosolo lamanjenje;

- Amatha kuchiza matenda a Parkinson, kusintha ntchito ya ma neurotransmitters mu ubongo wa odwala omwe ali ndi matenda a Parkinson, kuchepetsa kulumala kwakuthupi komanso zosowa zamankhwala;

- Therg aakulu fatigue syndrome (CFS), matenda a Alzheimer's ndi matenda amtima;

- Tetezani ku zotsatira zoyipa za mankhwala a Edzi otchedwa zidovudine (AZT);

- Tsutsani zakumwa za chiwindi;

- Kutopa kwapaulendo wandege

Beta-Nicotinamide adenine dinucleotide disodium mchere (NADH 2Na) mavuto:

Pakadali pano, mchere wa NADH disodium umawoneka wotetezeka kwa anthu ambiri akagwiritsidwa ntchito moyenera komanso mwachidule, mpaka sabata 12. Anthu ambiri samakumana ndi vuto lililonse akamamwa mankhwala omwe tsiku lililonse ndi 10 mg.

Komabe, palibe nkhokwe zokwanira zamagwiritsidwe ntchito ka mchere wa NADH disodium panthawi ya pakati komanso poyamwitsa., Chifukwa chake ayenera kukhala kumbali yotetezeka ndikupewa kugwiritsidwa ntchito.

Tsamba:

  • Birkmayer JG, Vrecko C, Volc D, Birkmayer W. Nicotinamide adenine dinucleotide (NADH) - njira yatsopano yothandizira matenda a Parkinson. Kuyerekeza pamlomo ndi ntchito ya makolo. Acta Neurol Scand Suppl 1993; 146: 32-5.
  • Budavari S, ed. The Merck Index. 12th. Whitehouse Station, NJ: Merck & Co, Inc., 1996.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Oral yafupika ya B-nicotinamide adenine dinucleotide (NADH) imakhudza kuthamanga kwa magazi, lipid peroxidation, ndi mbiri ya lipid mu makoswe oopsa (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Bushehri N, Jarrell ST, Lieberman S, et al. Oral yafupika ya B-nicotinamide adenine dinucleotide (NADH) imakhudza kuthamanga kwa magazi, lipid peroxidation, ndi mbiri ya lipid mu makoswe oopsa (SHR). Geriatr Nephrol Urol 1998; 8: 95-100.
  • Castro-Marrero J, Cordero MD, Segundo MJ, et al. Kodi pakamwa coenzyme Q10 kuphatikiza NADH yowonjezera kumatha kutopa ndi magawo amomwe am'magazi mu kutopa kwamatenda? Antioxid Redox Signal 2015; 22 (8): 679-85.
  • Dizdar N, Kagedal B, Lindvall B. Chithandizo cha matenda a Parkinson ndi NADH. Acta Neurol Scand 1994; 90: 345-7.

KULAMBIRA NDI KUSINTHA:

Nkhaniyi Ikagulitsidwa Kugwiritsa Ntchito Kafukufuku kokha. Migwirizano Yogulitsa. Osati Zongogwiritsa Ntchito Anthu, kapena Zamankhwala, Zoweta Zanyama, kapena Zogwiritsa Ntchito Panyumba.


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Kanema wa NADH 2Na (606-68-8)

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