Nicotinamide riboside mankhwala enaake (NR-CL) (23111-00-4)

March 11, 2020

Nicotinamide riboside (NR) ndi nicotinamide adenine dinucleotide (NAD +) yoyambitsa mavitamini. The …….

 


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

 

Kanotinamide riboside chloride (NR-CL) (23111-00-4) kanema

Nicotinamide riboside mankhwala enaake (NR-CL) (23111-00-4) S.zizindikiro

Name mankhwala Nicotinamide riboside mankhwala enaake (NR-CL) (23111-00-4)
Mankhwala Name NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium mankhwala enaake; Nicotinamide ribose mankhwala enaake; 3-Carbamoyl-1- (β-D-ribofuranosyl) pyridinium mankhwala enaake; 3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-ium mankhwala enaake; Nicotinamide BD Riboside mankhwala enaake (WX900111); NR-CL;
Nambala ya CAS 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
MUZIKONDWERETSA C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
Molecular Formula C11H15ClN2O5
Kulemera kwa maselo 290.7002
Misa ya Monoisotopic 290.066949 g / mol
Melting Point N / A
mtundu woyera
Stempage temp -20 ° C Freezer
ntchito zakudya zowonjezera zakudya, gawo la mankhwala

 

Kodi Nicotinamide riboside mankhwala enaake(NR-CL)?

Nicotinamide riboside (NR) ndi mtundu wongotulutsa kumene wa nicotinamide adenine dinucleotide (NAD +). Fomu la crystalline la NR chloride limatchedwa NIAGEN, womwe ndi mtundu wa nicotinamide riboside ndi gwero kuchokera pomwe nicotinamide mu mawonekedwe a nicotinic acid imatha kupezeka bioavava ndipo imadziwika kuti ndi yotetezeka (GRAS). NR chloride ndi mutu wa zidziwitso zatsopano ziwiri zophatikiza zakudya, zomwe zimagwiritsidwa ntchito kwambiri pazakudya.

Nicotinamide Riboside Chloride ndichinthu chachilengedwe chomwe chimapezeka mkaka. Amakhudzana kwambiri ndi niacin ndi mitundu ina ya vitamini B3. Kafukufuku wina apeza kuti Nicotinamide Riboside Chloride ili ndi mawonekedwe ena apadera omwe angalimbikitse kagayidwe kamunthu kothandiza mafuta owonjezera mafuta ndikupewa kunenepa. Kuphatikiza pa kuchepa thupi, zimathandizanso kukulitsa mphamvu ya minofu, kuwonjezera mphamvu zamagetsi, ndikuchepetsa zomwe zimayambitsa matenda ashuga.

Komanso, kafukufuku wokhudza anthu awonetsa kuti onse a Nicotinamide Riboside Chloride amakweza milingo ya NAD +, yomwe imathandizira kukongoletsa zochitika zina zokhudzana ndi zaka zambiri, ngakhale kuti posachedwa kwambiri kudziwa momwe zidzakhalire.

 

ubwino Nicotinamide riboside mankhwala enaake(NR-CL)

Nicotinamide riboside chloride ndi mtundu wa nicotinamide riboside, maubwino ake / ntchito ndi chimodzimodzi ndi nicotinamide riboside. Kuchita nawo kagayidwe kake m'thupi, kutha kugwiritsidwa ntchito pellagra kapena matenda ena amtundu wa niacin ndikutsitsa cholesterol ndi triglycerides m'magazi. Amagwiritsidwanso ntchito pochepetsa chiopsezo cha matenda amtima mwa anthu omwe ali ndi cholesterol yambiri yomwe idakhalapo ndi vuto la mtima. Nthawi zina amagwiritsidwa ntchito pochiza matenda amitsempha (atherosclerosis), kuteteza ubongo ndi chiwindi (mtima, matenda ashuga, matenda a Alzheimer's).

Kupatula apo, Nicotinamide riboside chloride imapindulitsanso anthu:

  • Chimbudzi choyenera ndi mayamwidwe a mapuloteni ndi mafuta;
  • Thandizani kusintha kofunikira kwa amino acid tryptophan kukhala niacin;
  • Kuchepetsa kusanza, ndikuchepetsa zotsatira za kutenga ma antidepressants chifukwa mkamwa youma komanso kuvuta kukodza;
  • Limbikitsani synthesis wa nucleic acid ndikuletsa kukalamba kwa minofu ndi ziwalo, potero ndikwaniritsa cholinga chachedwetsa ukalamba;
  • Pang'onopang'ono minofu minofu, kupindika ziwalo ndi dzanja ndi phazi neuritis;
  • Chithandizo cha kobadwa nako hypometabolism ndi kupititsa patsogolo kagayidwe;
  • Kupewa komanso chithandizo cha kuchepa kwa vitamini B6;
  • Chithandizo cha carpal tunnel syndrome;
  • Imathandizira kuchepetsa thupi komanso kumalimbitsa ntchito ya minofu.
  • Limbikitsani kulimbana kwa thupi ndi maselo a khansa
  • Pewani kumvetsera
  • Ndi okodzetsa achilengedwe.
  • Kumwa Mlingo waukulu kungathandize kuti musiye mankhwala osokoneza bongo komanso kuti mukhale ndi zotsatira zabwino.
  • Sinthani magwiridwe antchito a ma cell a epidermal, komanso ntchito za ma cell ena mthupi la munthu, kuti khungu liziwala.

 

Nicotinamide riboside mankhwala enaake(NR-CL) ntchito

Chifukwa Nicotinamide riboside chloride ili ndi mankhwala othandizira, imagwiritsidwa ntchito popititsa patsogolo zakudya, mankhwala ndi chakudya.

 

 

Tsamba:

  • Conze D, Brenner C, Kruger CL. Chitetezo ndi Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) mu Randomized, Double-Blind, Placebo -awule Clinical Tental of Healthy Overweight Adults. Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • Bogan, KL, Brenner, C. (2008). "Nicotinic acid, nicotinamide, ndi nicotinamide riboside: kuwunika kwama molekyulu a mavitamini a NAD + omwe amatsogolera m'thupi la anthu". Annu. Rev. Nutr. 28: 115-130. onetsani: 10.1146 / annurev.nutr.28.061807.155443. MAFUNSO OTHANDIZA:
  • Chi Y, Sauve AA (Novembala 2013). "Nicotinamide riboside, yomwe imapezeka m'zakudya, ndi vitamini B3 yomwe imakhudza mphamvu zamagetsi zamagetsi ndi chitetezo cha mthupi". Curr Opin Clin Nutruthi Kusamalira Metab. 16 (6): 657-61. onetsani: 10.1097 / MCO.0b013e32836510c0. PMID 24071780. (Adasankhidwa)