Nicotinamide riboside chloride (NR-CL) (23111-00-4)

March 11, 2020
SKU: 129938-20-1
5.00 kuchokera 5 kutengera 1 kasitomala mlingo

Nicotinamide riboside (NR) ndi mtundu wongotulutsa kumene wa nicotinamide adenine dinucleotide (NAD +) wotsogola. The …….


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

Kanotinamide riboside chloride (NR-CL) (23111-00-4) kanema

Nicotinamide riboside chloride (NR-CL) (23111-00-4) Szizindikiro

Name mankhwala Nicotinamide riboside chloride (NR-CL) (23111-00-4)
Mankhwala Name NRC; 3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride; Cotoride ya nitotinamide; 3-Carbamoyl-1- (β-D-ribofuranosyl) mankhwala a pyridinium chloride; 3-carbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-ium chloride; Nicotinamide BD Riboside Chloride (WX900111); NR-CL;
Nambala ya CAS 23111-00-4
InChIKey YABIFCKURFRPPO-IVOJBTPCSA-N
MUZIKONDWERETSA C1 = CC (= C [N +] (= C1) C2C (C (C (O2) CO) O) O) C (= O) N. [Cl-]
Molecular Formula C11H15ClN2O5
Kulemera kwa maselo 290.7002
Misa ya Monoisotopic 290.066949 g / mol
Melting Point N / A
mtundu woyera
Stempage temp -20 ° C Freezer
ntchito zakudya zowonjezera zakudya, gawo la mankhwala

Kodi Nicotinamide riboside chloride(NR-CL)?

Nicotinamide riboside (NR) ndi mtundu wongotulutsa kumene wa nicotinamide adenine dinucleotide (NAD +). Fomu la crystalline la NR chloride limatchedwa NIAGEN, womwe ndi mtundu wa nicotinamide riboside ndi gwero kuchokera pomwe nicotinamide mu mawonekedwe a nicotinic acid imatha kupezeka bioavava ndipo imadziwika kuti ndi yotetezeka (GRAS). NR chloride ndi mutu wa zidziwitso zatsopano ziwiri zophatikiza zakudya, zomwe zimagwiritsidwa ntchito kwambiri pazakudya.

Nicotinamide Riboside Chloride ndi mankhwala achilengedwe omwe amapezeka mkaka. Zimagwirizana kwenikweni ndi niacin ndi mitundu ina ya vitamini B3. Kafukufuku wina wapeza kuti Nicotinamide Riboside Chloride ali ndi zinthu zina zapadera zomwe zingalimbitse kagayidwe kazake kuti athandize kuwotcha mafuta ambiri komanso kupewa kunenepa. Kuphatikiza pa kuchepa thupi, zimathandizanso kuwonjezera minofu, kuwonjezera mphamvu zamagetsi, komanso kuchepetsa ziwopsezo za matenda ashuga.

Komanso, kafukufuku wokhudza anthu awonetsa kuti onse a Nicotinamide Riboside Chloride amakweza milingo ya NAD +, yomwe imathandizira kukongoletsa zochitika zina zokhudzana ndi zaka zambiri, ngakhale kuti posachedwa kwambiri kudziwa momwe zidzakhalire.

ubwino Nicotinamide riboside chloride(NR-CL)

Nicotinamide riboside chloride ndi mtundu wopanga wa nicotinamide riboside, maubwino / ntchito yake ndi yofanana ndi nicotinamide riboside. Ichita nawo kagayidwe kachakudya mthupi, imatha kugwiritsidwa ntchito popegra kapena matenda ena a niacin komanso kutsitsa cholesterol ndi triglycerides m'magazi. Amagwiritsidwanso ntchito kuchepetsa chiopsezo cha matenda a mtima mwa anthu omwe ali ndi cholesterol yayikulu omwe ali ndi vuto la mtima. Nthawi zina amagwiritsidwa ntchito pochiza matenda amitsempha yamagazi (atherosulinosis), kuteteza ubongo ndi chiwindi (zamtima, matenda ashuga, matenda a Alzheimer's).

Kupatula apo, Nicotinamide riboside chloride imapindulitsanso anthu:

  • Chimbudzi choyenera ndi mayamwidwe a mapuloteni ndi mafuta;
  • Thandizani kusintha kofunikira kwa amino acid tryptophan kukhala niacin;
  • Kuchepetsa kusanza, ndikuchepetsa zotsatira za kutenga ma antidepressants chifukwa mkamwa youma komanso kuvuta kukodza;
  • Limbikitsani synthesis wa nucleic acid ndikuletsa kukalamba kwa minofu ndi ziwalo, potero ndikwaniritsa cholinga chachedwetsa ukalamba;
  • Pang'onopang'ono minofu minofu, kupindika ziwalo ndi dzanja ndi phazi neuritis;
  • Chithandizo cha kobadwa nako hypometabolism ndi kupititsa patsogolo kagayidwe;
  • Kupewa komanso chithandizo cha kuchepa kwa vitamini B6;
  • Chithandizo cha carpal tunnel syndrome;
  • Imathandizira kuchepetsa thupi komanso kumalimbitsa ntchito ya minofu.
  • Sinthani thupi kukana maselo a khansa
  • Pewani kumvetsera
  • Ndi okodzetsa achilengedwe.
  • Kumwa Mlingo waukulu kungathandize kuti musiye mankhwala osokoneza bongo komanso kuti mukhale ndi zotsatira zabwino.
  • Sinthani magwiridwe antchito a ma cell a epidermal, komanso ntchito za ma cell ena mthupi la munthu, kuti khungu liziwala.

Nicotinamide riboside chloride(NR-CL) ntchito

Chifukwa Nicotinamide riboside chloride ili ndi mankhwala opindulitsa, nthawi zambiri imagwiritsidwa ntchito muzakudya zowonjezera, mankhwala ndi malo ogulitsa.

Tsamba:

  • Conze D, Brenner C, Kruger CL. Chitetezo ndi Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) mu Randomized, Double-Blind, Placebo -awule Clinical Tental of Healthy Overweight Adults. Sci Rep. 2019 Jul 5; 9 (1): 9772. doi: 10.1038 / s41598-019-46120-z. PMID: 31278280 PMCID: PMC6611812.
  • Bogan, KL, Brenner, C. (2008). "Nicotinic acid, nicotinamide, ndi nicotinamide riboside: kuwunika kwa mavitamini a NAD + omwe ali patsogolo pazakudya za anthu". Annu. Rev. Nutr. 28: 115-130. doi: 10.1146 / annurev.nutr.28.061807.155443. PMID 18429699.
  • Chi Y, Sauve AA (Novembala 2013). "Nicotinamide riboside, michere ya zakudya m'zakudya, ndi vitamini B3 yokhala ndi mphamvu zama metabolism ndi neuroprotection". Curr Opin Clin Nutr Metab Care. 16 (6): 657-61. doi: 10.1097 / MCO.0b013e32836510c0. PMID 24071780.