Mchere wa NADP disodium (24292-60-2)

March 15, 2020
SKU: 164656-23-9

Nicotinamide adenine dinucleotide phosphate (NADP +) ndi cofactor ogwiritsidwa ntchito pamavuto a anabolic. β-Nicotinamide adenine ……


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

NADP disodium mchere (24292-60-2) kanema

β-Nicotinamide adenine dinucleotide phosphate disodium mchere (mchere wa NADP disodium) Szizindikiro

Name mankhwala salt-Nicotinamide adenine dinucleotide phosphate disodium salt (mchere wa NADP disodium)
Mankhwala Name Disodium ya NADP; Nadide phosphate disodium; NADP; β-NADP; Triphosphopyridine nucleotide disodium mchere;
Nambala ya CAS 24292-60-2
InChIKey Gawo #: UNRRSQIQTVFDLS-WUEG
MUZIKONDWERETSA C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)([O-])OP(=O)(O)OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O)C(=O)N.[Na+].[Na+]
Molecular Formula C21H26N7Na2O17P3
Kulemera kwa maselo 787.37
Misa ya Monoisotopic 787.039342 g / mol
Melting Point 175-178 ° C
mtundu Yellow
Stempage temp -20 ° C
Water Kutupa > 50 g / L
ntchito Coenzyme mu mawonekedwe aerobic ndi anaerobic

Kodi mchere wa β-Nicotinamide adenine dinucleotide phosphate disodium salt (NADP disodium salt) ndi uti?

Nicotinamide adenine dinucleotide phosphate (NADP +) ndi cofactor ogwiritsidwa ntchito pamavuto a anabolic. β-Nicotinamide adenine dinucleotide phosphate disodium mchere ndi mchere wa NADP +, ndi coenzyme yofunikira kuti pakhale mowa wambiri wa glucose komanso oxidative dehydrogenation ya zinthu zina. Ndipo zimachitika kwambiri pamankhwala amoyo, makamaka m'chiwindi.

Nicotinamide adenine dinucleotide phosphate (NADP) ndi NADPH amapanga gulu la redox. Chiwerengero cha NADPH / NADP chimayang'anira intracellular redox yothekera, makamaka kuyankha kwa anaerobic, potero kukhudza kuyankha kwa metabolic mthupi. Zitsanzo ndi lipid ndi syntic acid synthesis. NADP ndiwotengera ma coenzyme m'makina osiyanasiyana a cytochrome P450 ndi oxidase / reductase reaction system monga thioredoxin reductase / thioredoxin system.

NADPH imathandizira kuchepetsa kufanananso kwa mitundu iwiri yamagazi yogwirizana ndipo imapatsanso zotsatira za redox kuteteza kuwopsa kwa mitundu yogwiritsa ntchito mpweya wabwino (ROS), potero kubwezeretsanso glutathione (GSH). Amagwiritsidwanso ntchito munjira za anabolic monga cholesterol synthesis ndi mafuta acids Chain.

Kuphatikiza apo, dongosolo la NADPH limakhalanso ndi udindo wopanga ma radicals aulere m'maselo a chitetezo cha mthupi kudzera mwa NADPH oxidase. Ma radicals aulere awa amagwiritsidwa ntchito kuwononga tizilombo toyambitsa matenda m'njira yotchedwa kupumira. Ndi kuchepetsa wofanana ndi gwero la cytochrome P450 hydroxylated aromatics, ma steroid, alcohols, ndi mankhwala osokoneza bongo.

ntchito wa β-Nicotinamide adenine dinucleotide phosphate disodium mchere

Nicotinamide adenine dinucleotide phosphate (NADP) ndi NADPH amapanga gulu la redox. NADP / NADPH ndi coenzyme yomwe imachirikiza mayankho a redox kudzera pa mayendedwe a ma elekitirogiramu munjira zambiri, makamaka zochita za anaerobic monga lipid ndi syntic acid synthesis. NADP / NADPH ndi banja la coenzyme m'machitidwe osiyanasiyana a cytochrome P450 ndi oxidase / reductase reaction, monga thioredoxin reductase / thioredoxin system.

Ma enzyme ena omwe amagwiritsa ntchito NADP ngati coenzyme ndi awa: Mowa dehydrogenase: Wodalirika wa NADP; Aromatic ADH: NADP wodalirika; Forteroxin-NADP reductase; L-Fucose dehydrogenase; Mbiri; Galactose-1-phosphate uridyl kutulutsa; Glucose dehydrogenase; L-Glutamic dehydrogenase; Glycerol dehydrogenase: NADP yapadera; Isocitric dehydrogenase; Ma enzymes a Malic; 5,10-Methylenetetrahydrofolate dehydrogenase; 6-Phosphogluconate dehydrogenase ndi Succinic semialdehyde dehydrogenase.

Tsamba:

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