+ 86 (1812) 4514114 info@phcoker.com

Mafuta akuluakulu a Tadalafil (171596-29-5)

(1 kasitomala review)

Mafuta akuluakulu a Tadalafil omwe amagwiritsa ntchito dzina la Cialis amagwiritsidwa ntchito pochiza matenda osokoneza bongo (impreence) ndi zizindikiro za prostatic zoopsa .........


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum
mphamvu: 1190kg / mwezi

Kufotokozera

Tadalafil ufa video

Mfundo Zachidule

Name mankhwala Tadalafil powder
Mankhwala Name (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methylpyrazino[1′,2′:1,6]pyrido[3,4-b]indole-1,4-dione
Brand NAme Cialis, Adcirca
Kalasi ya Mankhwala PAH, PDE-5 Inhibitors; Phosphodiesterase-5 Enzyme Inhibitors
Nambala ya CAS 171596-29-5
InChIKey WOXKDUGGOYFFRN-IIBYNOLFSA-N
Maselo Fmphutsi C22H19N3O4
Maselo Wasanu ndi atatu 389.4
Misa ya Monoisotopic 389.138 g / mol
Kusungunula Pmafuta 298-300 ° C
Fkubwezeretsanso Pmafuta 2 ℃
Halimo Half-Life hours 17.5
mtundu Yoyera mpaka Yoyera Yogwedeza Mpweya Wolimba
Szovuta Sungunulani mu DMSO (78 mg / ml pa 25 ° C), methanol, madzi (<1 mg / ml pa 25 ° C), dichloromethane, ndi ethanol (<1 mg / ml pa 25 ° C)
Smazunzo Tkutentha Sungani kutentha kutentha pakati pa 59 ° F ndi 86 ° F (15 ° C ndi 30 ° C). Musasunge mankhwala awa kumalo amvula kapena amchere.
Tadalafil Amalingaliro Mafuta akuluakulu a Tadalafil, mapepala ogonana, ma khofi akugonana, ndi zina zotero.

Kufotokozera

(6-trans) -6- (1,3-benzodioxol-5-yl) -2,3,6,7,12,12-hexahydro-2-methyl-pyrazino [1 ', 2': 1,6] pyrido [3,4-b] indole-1,4-dione ( Cialis), ndi mtundu wa PDE5 inhibitor ndi mankhwala ovomerezeka pamlomo. Ndizochokera ku b-carboline ndipo imasiyanasiyana ndi vardenafil (Levitraw) ndi sildenafil (Viagraw), zonsezi ndi PDE5 zowonongeka pogwiritsa ntchito piritsi pyrimidine. Tadalafil powder (CAS 171596-29-5) imapangitsa kuti magazi alowe mu corpus cavernosum potulutsa mitsempha ya magazi, ndipo izi zimapangitsa munthu kukwaniritsa. Tadalafil powder inavomerezedwa ndi United States (US) Chakudya ndi Drug Administration (FDA) ku 2003 pofuna kuchiza matenda osokoneza bongo (ED), ndipo anagulitsa padziko lonse pansi pa dzina la Cialis. Amagwiritsidwanso ntchito pochiza matenda opatsirana kwambiri ndi benign prostatic hyperplasia, vuto limene prostate gland limakula, zomwe zimayambitsa mavuto.

Mbali ya pharmacologic yosiyana ndi Tadalafil ndiyo yautali kwambiri (maola 17.5) poyerekeza ndi Viagra ndi Levitra (maola 4-5). Kutalika kwa theka la moyo kumakhalapo nthawi yaitali ndipo ndi mbali yodziwika ndi dzina lachidziwitso la "mapiritsi a mapeto a sabata." Kutalika kwa theka la moyo ndilo maziko a kafukufuku wamakono wa ntchito ya tadalafil mu mitsempha yowopsa kwambiri. mankhwala amodzi patsiku.

Njira yogwira ntchito

Penile erection pakukakamiza kugonana kumatheka chifukwa cha kumasuka kwa mitsempha ya penile ndi corpus cavernosal yosalala minofu, zomwe zimapangitsa kuwonjezeka kwa magazi ku limba. Kupumula uku kumapangitsa kuwonjezeka kwamagazi kudzera m'mitsempha ya penile, pamene magazi awa amadzaza zipinda ziwiri mkati mwa mbolo yotchedwa corpora cavernosa. Pamene zipinda zimadzaza magazi, mbolo imakula molimba. Kukonzekera kumathera pamene mgwirizano wa minofu ndi magazi ophatikizidwa amatha kutuluka mumtsempha wa penile.

Yankho limeneli ndiloperekedwa ndi kutulutsidwa kwa nitric oxide (NO) kuchokera kumapeto kwa mitsempha ndi maselo a endothelial, omwe amachititsa kuti kaphatikizidwe ka cGMP mu maselo osakanikirana ndi mitsempha ndiyomwe imayendetsa mitsempha ya magazi yomwe imanyamula magazi kuchokera ku mbolo. Cyclic GMP imachititsa kuti thupi liziyenda bwino komanso kuwonjezeka kwa magazi kulowa mu corpus cavernosum, ndipo imanyozedwa ndi cGMP phosphodiesterase mtundu wa 5 (PDE5) mu corpus cavernosum yomwe ili pafupi ndi mbolo. Tadalafil imaletsa PDE5 ndipo imapangitsa kuti pakhale kuchuluka kwa cGMP. Tadalafil imasiya PDE5 kuti iwononge cGMP ndipo imawonjezera cGMP yomwe ikupezeka kuti ikwaniritse ntchito ya erectile ndipo imapangitsa kuti erection ipitirire kwa nthawi yayitali.

Komabe, pamene hafu ya moyo wa Tadalafil ndi yochepa, zotsatira zake zimatha patsiku la masiku 2 kupanga PDE5 kubwerera ndipo umoyo wanu wa kugonana - umakula. Mungafunike kutenga nthawi yaitali kuti mukwaniritse zomwe mumafuna, monga masiku amphamvu a Cialis 4-5 masiku a 4-5.

ntchito

  • Erectile kulephera (ED)
  • Kupanga mankhwala oopsa
  • Benign Prostatic hyperplasia
  • Analgesic
  • Kuzimitsa kwa Norepinephrine
  • Mu-opiod receptor agonist

Analimbikitsa Tadalafil powder Mlingo

Cialis imakhala ndi mapiritsi a chikasu, ovekedwa ndi mafilimu komanso amondi m'zigawo za 5, 10 ndi 20 milligram (mg). Ndalama yoyamba yoyamba ya Cialis ufa kuti igwiritsidwe ngati momwe osowa ambiri amagwiritsira ntchito ndi 10 mg, kutengedwa musanakhalepo kugonana.

Mlingo woyamba ndi ma XMUMX milligrams (mg) osachepera mphindi 10 musanayambe kugonana. Mlingowo ukhoza kuwonjezeka mpaka 30 mg kapena kuchepa kwa 20 mg, pogwiritsa ntchito mphamvu ndi kulekerera. Koma, chiwerengero chachikulu cha 5 mg ndi mlingo umodzi. Nthawi zambiri odwala ambiri amawadziwitsa nthawi zambiri patsiku. Sitiyenera kutenga mlingo umodzi pa maola 20. Odwala omwe amayembekezera kuti azigonana kamodzi pawiri pa sabata akhoza kutenga mlingo wa 24 mg, ndipo izi zikhoza kuchepetsedwa kukhala 5 mg kamodzi tsiku ndi tsiku, malingana ndi momwe akuchitira.

Nkhumba yamtengo wapatali yogwiritsiridwa ntchito monga momwe ikufunira inasonyezedwa kuti imapangitse ntchito erectile poyerekeza ndi placebo mpaka maola 36 akutsatira dosing. Choncho, pochenjeza odwala kuti azigwiritsa ntchito bwino ufa wa Cialis, izi ziyenera kuganiziridwa.

Ndikoyenera kudziwa kuti kusuta sikudzachitika pokhapokha kutenga mapiritsi. Ndipo musatengere Cialis kuti musagwire ntchito yosavuta ngati mukugwiritsa ntchito Adcirca kuti mukhale ndi matenda oopsa kwambiri. Kupatulapo, Tadalafil chifukwa cholephera kugwiritsira ntchito erectile ndikugwiritsidwa ntchito ndi akuluakulu omwe ali ndi zaka 18 zaka zambiri.

ubwino

• Tadalafil powder akhoza kuthandiza kutulutsa minofu mu prostate yanu ndi chikhodzodzo. Izi zingathandize kusintha zizindikiro za BPH yanu.

• Kuonjezera zizindikiro za ED, ufa wa tadalafil umathandiza kuwonjezera magazi kupita ku mbolo. Izi zingakuthandizeni kupeza ndi kusunga erection. Kwa tadalafil powder kukuthandizani kuti mukhale ndi erection, muyenera kukwatira.

• Kwa PAH, ufa wa tadalafil umayesetsa kukonzanso luso lanu lochita masewera olimbitsa thupi m'mapapo anu. Izi zimapangitsa magazi kuyenda.

Zotsatira zoyipa

Pamodzi ndi zotsatira zake zofunikira, mankhwala akhoza kuchititsa zina zosayenera. Ngakhale kuti zovuta zonsezi sizitha kuchitika, ngati zikuchitika zimakhala zofunikira kuchipatala. Chonde onani zotsatira zotsatirazi za tadalafil powder:

Zotsatira zofala

▪ kumutu

▪ amadwala m'mimba

▪ ululu wammbuyo

▪ minofu ya minofu

▪ kusamba (khungu lofiira)

▪ zonyansa kapena mphuno

▪ m'mimba

Zotsatira zoopsa koma zoopsa

Erection yaitali yomwe ingabweretse kuwonongeka kwa mbolo, mavuto a masomphenya, ndi kutaya kwa kumva.

Ngati zotsatirazi ndi zofewa, zimatha kutha masiku angapo kapena masabata angapo. Ngati ali ovuta kwambiri kapena osapitako, lankhulani ndi dokotala kapena wamankhwala.

Anthu omwe ali ndi zifukwa izi sayenera kutenga Cialis pokhapokha ngati dokotala akugwirizana:

Matenda a mtima, angina, kapena mtundu uliwonse wa matenda a mtima

Kuthamanga kwapamwamba kapena kutsika kwa magazi

Kusintha mtima kwa mtima kapena kupweteka kwa miyezi mkati mwa miyezi yotsiriza ya 6, kapena matenda a myocardial mkati mwa miyezi yotsiriza ya 3

Matenda a maselo a matenda, matenda ena a myeloma, hemophilia, khansa ya m'magazi, kapena matenda ena a magazi

Matenda a chiwindi kapena impso

Chilonda cha m'mimba

Retinitis pigmentosa

Kuwonongeka kwa chiwalo cha mbolo, monga matenda a Peyronie

Matenda aliwonse omwe adalangizidwa kuti asagone nawo

Kugwirizana kwa Tadalafil

Mukamagwiritsa ntchito tadalafil, pangakhale mankhwala ena omwe angakhudze mankhwala, omwe angapangitse zotsatirapo. Kugwiritsa ntchito mankhwala osokoneza bongo kungasinthe momwe mankhwala anu amagwiritsira ntchito kapena kuwonjezera chiopsezo chanu chowopsa.

Tadalafil ali ndi mphamvu zochepa zowonjezera kuchepetsa kuchepetsa kuthamanga kwa magazi. Tadalafil ingayambitse kuchepa kwa magazi pamene ikugwiritsidwa ntchito ndi nitrates, zomwe zingayambitse chizungulire, kutaya mtima, komanso kudwala matenda osokonezeka mtima. Musagwiritse ntchito tadalafil ndi zina mwa izi: mankhwala ena ogwiritsidwa ntchito pochizira chifuwa / angina (nitrates monga nitroglycerin, isosorbide), mankhwala osangalatsa omwe amatchedwa "poppers" omwe ali ndi amyl kapena butyl nitrite.

Ngati mukugwiritsanso ntchito mankhwala a alpha blocker (monga doxazosin, tamsulosin) kuti muzitha kutulutsa prostate / BPH yothamanga kapena kuthamanga kwa magazi, kuthamanga kwa magazi kungakhale kotsika kwambiri komwe kungachititse kuti mukhale ndi chizungulire kapena kutaya. Dokotala wanu angayambe kulandira chithandizo ndi mankhwala ochepa a tadalafil kapena kusintha mankhwala anu ochepetsa mankhwala a alpha kuti muchepetse chiopsezo cha kutsika kwa magazi.

M'maphunziro azachipatala, ziwerengero zazikulu zowonjezera zinafotokozedwa ku 36 h potsatira mankhwala osokoneza bongo. Tadalafil imayambitsa matenda ambiri m'chiwindi ndi CYP3A4 ku zinthu zomwe sizilimbana ndi PDE5 ndipo zimadulidwa makamaka ngati metabolites mu nyansi ndi mkodzo. Ma pharmacokinetics a tadalafil sakhudzidwa ndi zinthu monga kudya ndi kumwa mowa, zaka, kukhala ndi matenda a shuga, ndi kuchepa kwachangu. Zochitika zovuta zokhudzana ndi mankhwala osokoneza bongo ndizopweteka, kupweteka kumbuyo, kupweteka, ndi myalgia. Pa 10 ndi 20 mg Mlingo, Tadalafil sichimakhudza kwambiri kuthamanga kwa magazi ndi kuthamanga kwa mtima ndipo sizimapangitsa kuti pakhale kuchuluka kwa matenda a myocardial infarction. Malipoti amtundu wa mazira opitirira nthawi yaitali kuposa 4 h ndi priapism amadziwika pogwiritsa ntchito tadalafil. Kupembedza, ngati sikupanda kuchiritsidwa bwino, kungapangitse kuwonongeka kosasinthika kwa mitsempha ya erectile. Odwala omwe ali ndi erection woposa wamkulu wa 4 amalangizidwa kufunafuna chithandizo chamankhwala. Odwala matenda a shuga, kusintha kwa erectile kugwira ntchito ndi tadalafil mosasamala mtundu wa shuga ndi mtundu wa mankhwala a shuga.

Mankhwala ena akhoza kuthandizira kuchotsa tadalafil m'thupi lanu, zomwe zingakhudze momwe tadalafil imagwirira ntchito. Zitsanzo zimaphatikizapo mankhwala a azole (monga itraconazole, ketoconazole), macrolide antibiotics (monga clarithromycin, erythromycin), HIV protease inhibitors (monga fosamprenavir, ritonavir), kachirombo ka hepatitis C protease inhibitors (monga boceprevir, telaprevir), rifampin .

Musamamwe mankhwalawa ndi mankhwala ena aliwonse omwe ali ndi tadalafil kapena mankhwala ena ofanana ndi omwe amachititsa kuti matenda a Erectile asamayende bwino-ED kapena matenda oopsa (monga sildenafil, vardenafil).

Ponena za kugonana kwa tadalafil ndi mankhwala ena ali ndi zochuluka kwambiri, ngati mukufuna kugwiritsa ntchito mankhwala ndi tadalafil powder (CAS 171596-29-5), choyamba kumbukirani kukaonana ndi dokotala ndipo adzakupatsa uphungu komanso wodalirika malangizo. Kubwereza Kwambiri Kwambiri Kwa Tadalafil Generic Kwa ED

Dziwani zambiri

Tadalafil ufa, sildenafil powder, ndi vardenafil powder onse amachita mwa kuletsa puloteni PDE5, koma mankhwalawa amalepheretsanso mitundu ya PDE michere 6, 1, ndi 11 mosiyanasiyana. Mwachitsanzo, Sildenafil ndi vardenafil amalepheretsa PDE6, nyamayi yomwe imapezeka mu diso, kuposa tadalafil. Owerenga ena a sildenafil amatha kuona bluish tinge ndipo amakhala ndi mphamvu zowonjezera chifukwa cha PDE6. Kuwonjezera apo, Sildenafil ndi vardenafil amalepheretsanso PDE1 kuposa tadalafil. PDE1 imapezeka mu ubongo, mtima, ndi minofu yosalala. Zimaganiziridwa kuti kutetezedwa kwa PDE1 ndi sildenafil ndi vardenafil kumatsogolera ku vasodilation, flushing, ndi tachycardia.

Poyerekeza ndi machitidwe a PDE6 ndi PDE1, tadalafil inkagwira ntchito kwambiri pa PDE11. PDE11 imasonyezedwa minofu ya chifuwa, prostate, chiwindi, impso, chifuwa cha pituitary, ndi mayesero. Komabe, zotsatira za thupi loletsa PDE11 sizidziwika.


=

Mafotokozedwe ndi zolemba zamagulu

Kubwereza Kwambiri Kwambiri Kwa Tadalafil Generic Kwa ED

Zothandizira

  • 1.National Center For Information Technology, US. Laibulale ya National Medicine, Tadalafil, Pubchem Zina 1-10.
  • 2.Evelyn C. Cortez, CIALIS (Tadalafil): Ntchito, Mlingo, Zotsatira Zachigawo Zomwe Zimagwiritsidwa Ntchito ndi Kugula Generic Cialis (Tadalafil), Viagra (Sildenafil), ndi Zida Zina Zabwino Zotsika ndi Zosavuta pa Intaneti, Zopangidwa, 13 Dec 2017, tsamba 5-3
  • 3.James Lee Anderson, Cialis, Tadalafil: Amachita Erectile Dysfunction, Zizindikiro za Benign Prostatic Hyperplasia, ndi Pulmonary Arterial Hypertension, BuildSpace Independent Publishing Platform, 26 Mar 2015, tsamba 5-47.

1 review kwa Mafuta akuluakulu a Tadalafil (171596-29-5)

  1. phcoker -

    Tili ndi ma Raw Tadalafil powder kuyesa, kuyesa zotsatira kumasonyeza kwambiri khalidwe ndi chiyero!

Kuwonjezera ndemanga

Anu email sati lofalitsidwa. Amafuna minda amalembedwa *

Shangke Chemical ndi makampani apamwamba kwambiri omwe amagwiritsa ntchito mankhwala omwe amathandiza kwambiri. Pofuna kuyendetsa khalidweli panthawi yopanga, akatswiri ambiri odziwa bwino ntchito, makina oyambirira kupanga zipangizo komanso ma laboratori ndi mfundo zofunika kwambiri.

Lumikizanani nafe