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Mkaka wa AOD 9604 ufa (221231-10-3)

AOD 9604 ufa ndi mawonekedwe osinthika Hormone yomwe ndi 191 amino acid peptide. Zomaliza za 15 amino acid (176-191) ....


Chikhalidwe: Mu Kupanga Misa
Zokonzedwa ndi Zokonzedweratu Zopezeka
mphamvu: 1277kg / mwezi

Kufotokozera

Mawotchi a AOD 9604 powder (221231-10-3) kanema

Mkaka wa AOD 9604 ufa (221231-10-3) Kufotokozera

Mafuta akuluakulu a AOD 9604 powder (221231-10-3) ndi mankhwala omwe amatsutsana ndi kunenepa kwamtundu wa peptide.

AOD 9604 ufa ndi mawonekedwe osinthika Hormone yomwe ndi 191 amino acid peptide. Zomaliza za 15 amino acid (176-191) za polytheptide ya Growth Hormone zatulutsidwa monga peptide yapadera ndipo imatchedwa GH Frag 176-191 kapena AOD 9604.

Zimagwiritsa ntchito kutsanzira njira ya chilengedwe yotchedwa Growth Hormone yomwe imayendetsa mafuta amtundu wa mafuta koma popanda zotsatira zowonjezera shuga kapena kukula kwa magazi komwe kumawoneka ndi Hormone yosawonjezereka. Monga kukula kwa Hormone, yaiwisi ya AOD 9604 imayambitsa lipolysis (kuwonongeka kapena kuwonongeka kwa mafuta) ndipo imaletsa lipogenesis (kusinthidwa kwa zipangizo za nonfat ku mafuta a thupi) zonse mu kuyesa ma laboratory ndi nyama ndi anthu. Zotsatira zaposachedwapa zasonyeza, kuwonjezera pa katundu wake wotayika, AOD 9604 ikupanga zinthu zina zambiri zowonongeka zogwirizana ndi kukula kwa hormone. Pakalipano mayesero akuyambanso kusonyeza kugwiritsa ntchito AOD 9604 mu osteoarthritis, hypercholesterolemia, kukonzanso mafupa ndi khungu. Mafuta a AOD 9604 powder (221231-10-3) ali ndi mbiri yabwino kwambiri yoteteza chitetezo, posachedwapa kupeza malo GRAS ku United States.

Mafuta akuluakulu a AOD 9604 powder, omwe amadziwikanso kuti Tyr-hGH Frag 176-191 adatsimikiziridwa kukhala ndi mphamvu yowononga mafuta, popanda kupanga chilakolako chodyera. Sichikhudza shuga kapena minofu kukula kwa magazi. AOD-9604 imayambitsa kuwonongeka ndi kutentha kwa mafuta (oxidation), mwa njira yomwe siigwiritsira ntchito HGH receptor. Icho chiri ndi kayendedwe kake kopanda HGH. Maphunziro a Laboratory pa makoswe, nkhumba, agalu & anthu adziwe njira ya AOD-9604 yomwe imayambitsa mafuta kutulutsa mafuta owonjezera kwambiri ndipo amagwira ntchito kuti achepetse mafuta atsopano m'maselo ambiri komanso kuwonjezeka kwa mafuta. Chimene chiri chodabwitsa pa AOD-9604 ndi mphamvu yake yochepetsera m'masitolo a m'mimba

Mkaka wa AOD 9604 ufa (221231-10-3) Szizindikiro

Name mankhwala AOD 9604 ufa
Mankhwala Name UNII-7UP768IP4M;7UP768IP4M
L-tyrosyl-L-leucyl-L-arginyl-L-isoleucyl-L-valyl-L-glutaminyl-L-cysteinyl-L-arginyl-L-seryl-L-valyl-L-alpha-glutamyl-glycyl-L- seryl-L-cysteinyl-glycyl-L-phenylalanine (7-> 14) -disideidedi.
Zotsatira Tyr-Leu-Arg-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
Brand NAme N / A
Kalasi ya Mankhwala anti-obesity peptide
Nambala ya CAS 221231-10-3
InChIKey GVIYUKXRXPXMQM-BPXGDYAESA-N
Maselo Fmphutsi C78H123N23O23S2
Maselo Wasanu ndi atatu 1815.1 g / mol
Misa ya Monoisotopic 1813.86 g / mol
Kusungunula Pmafuta 191.0 ~ 193.0ºC
Fkubwezeretsanso Pmafuta N / A
Halimo Half-Life N / A
mtundu White crystalline powder; Powder Lyophilized
Szovuta Sungunulani mumadzi kapena 1% acetic acid
Smazunzo Tkutentha Inatsekedwa, pansi pa 2 ~ 8 C yosungidwa
Amalingaliro Kuchepetsa kunenepa

Peptideyi imakhala ndi chiwerengero cha amino acid chomwe chimatsanzira chigawo cha lipolytic cha hormone ya kukula kwaumunthu (gawo la hormone iyi yomwe imalingalira kuti ndiloyambitsa mafuta) ndipo imalimbikitsidwa mosiyana ngati kuperewera kwa thupi, monga chithandizo cha minofu , ndi chithandizo cha osteoarthritis ndi opanga. Amadziwikanso ngati lipotropin ndi kachidutswa ka Tyr-hGH, ndipo nthawi zambiri amapezeka masiku ano ngati kirimu kapena mankhwala.


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Mafotokozedwe ndi zolemba zamagulu

Peptide AOD 9604 Choonadi: Kodi Chimabweretsa Chiyani Pambuyo Pogwiritsa Ntchito AOD 9604?

Zothandizira

  1. Stier, H., Vos, E., ndi Kenley, D. (2013). Chitetezo ndi Kulephereka kwa Hexadecapeptide AOD-9604 mwa Anthu. Journal of Endocrinology ndi Metabolism.
  2. Ng, FM, Sharma, L., Sun, J., Jiang, WJ, Libinaka, R., ndi Gianello, R. (2000). Maphunziro a Zamadzimadzi a Lipolytic Domain (AOD-9604) ya Hormone ya Kukula kwa Anthu.
  3. Heffernan, M., Ng, FM, Summers, RJ, Thorburn, A., et al. (2001). Zotsatira za Mankhwala a GH ndi Lipolytic Fragment (AOD-9604) pa Lipid Metabolism Potsatira Chithandizo Chachilendo M'magulu Omwe ndi β3-Nkhoswe Zowonongeka.
  4. Heffernan, M., Gianello, R., Ng, FM, et al. (2001). Kuwonjezeka kwa Kutayidwa kwa Mafuta ndi Kutaya Kwambiri Kwambiri M'magulu Omwe Amayambitsa Chithandizo Chachilendo ndi Kukula kwa Hormone ya Anthu kapena Modified C-Terminal Fragment. International Journal of Obesity.

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