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Mpweya wa Tianeptine wamchere wa sodium (30123-17-2)

(1 kasitomala review)

Tianeptine sodium salt powder ndi tricyclic compound, ndi otsogolera osankhidwa a 5-HT (serotonin; sc-201146) omwe amapezeka mu vitro ....


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum
mphamvu: 1290kg / mwezi

Kufotokozera

Mazira a Tianeptine a sodium salt (30123-17-2) kanema

Mafuta a tianeptine a sodium salt (30123-17-2) Malangizo

Name mankhwala Mpweya wa Tianeptine wamchere wa sodium
Mankhwala Name Tianeptine sodium; Tianeptine mchere wa sodium; 30123-17-2; Msewu; Coaxil;
Brand NAme N / A
Kalasi ya Mankhwala N / A
Nambala ya CAS 30123-17-2
InChIKey HNTRDGDHBBFLPG-UHFFFAOYSA-M
Maselo Fmphutsi C21H24ClN2NaO4S
Maselo Wasanu ndi atatu 458.93
Misa ya Monoisotopic 458.104 g / mol
Kusungunula Pmafuta 1800C
WiritsaniIng Pmafuta 609.2 ° C pa 760 mmHg
Halimo Half-Life N / A
mtundu Yoyera mpaka wofiira
Szovuta DMSO: ≥20mg / mL
Smazunzo Tkutentha Desiccate pa RT
Amalingaliro Tianeptine sodium salt ufa ndi mchere wa Tianeptine.

Tianeptine ndi yodetsa nkhawa.

Mafuta a tianeptine a sodium salt (30123-17-2)

Tianeptine mchere wa sodium ndi mchere wa Tianeptine. Tianeptine, gulu la tricyclic, ndi wotsogolera wotsogolera wa 5-HT (serotonin; sc-201146) omwe amapezeka mu vitro komanso mu vivo. Kuwonjezera apo, Tianeptine imadziwika kuti ndiyo njira yodzitetezera ya dopamine yomwe ikuwoneka ndipo ikufanana ndi amineptine. Tianeptine imakhudza kwambiri monoamine. Mu kafukufuku wogwiritsa ntchito mankhwala oyeretsa a khungu, Tianeptine inanenedwa kuti imapangitsa serotonin kukonzekera m'madera a ubongo. Ma synaptosomes oyera anapezeka pa makoswe ndipo ankagwiritsidwa ntchito ndi tritium-yotchedwa 5-HT ndi Tianeptine mu vitro. The synaptosomom kenaka anafufuzidwa kuti athandizidwe ndi kutulutsidwa kwa 5-HT pogwiritsa ntchito pepala la scintillation.

Yaiwisi Tianeptine ndi sodium mchere ufa ndi atypical antidepressant ndi zochita zosiyanasiyana, makamaka pa system.It glutamatergic attenuates glutamate kumasuka ndi modulates ntchito ya AMPA receptor.Tianeptine komanso amachita ngati agonist wa cholandilira μ-opioid (EC50s = 194 ndi 641 nM yowalandira anthu ndi mbewa, motsatira). Ndi othandiza kwambiri monga fluoxetine m'mayendedwe a post-traumatic stress disorder.

Tianeptine ndi sodium mchere ali luso nootropic ponena za anthu amene cognition ndi zoipa mwapeza ndi matenda a maganizo ndi amatha kusintha cholinga ndi ndende ku anthu amene ali tcheru osauka chimakwirira komanso.

Tianeptine sodium salt ufa (30123-17-2) Njira yogwira ntchito

Kafukufuku waposachedwapa amasonyeza kuti tianeptine imakhala ngati agonist wathunthu mu mtundu wa opioid receptor (MOR). Tianeptine yatsutsa monoaminergic hypothesis ya kupsinjika maganizo, komanso njira zothandizira kwambiri za monoaminergic zomwe zimawathandiza kuti azidziwidwa bwino kwambiri. Mwachindunji, mankhwalawa akuganiza kuti mosalekeza akusintha glutamate receptor kutuluka kwa hippocampal ya CA3 yogwirizana ndi mgwirizanowo. kafukufuku Current zikusonyeza kuti tianeptine umabala zotsatira zake antidepressant mwa kusinthasintha mawu a ntchito glutamate cholandilira (mwachitsanzo, AMPA zolandilira ndi NMDA zolandilira) kusintha amasulidwe ubongo anachokera neurotrophic Chinthu (BDNF), zomwe zotsatira ubongo plasticity. Kafukufuku waposachedwapa wothandizira kuti ntchito ya tianeptine ikhale yogwirizana ndi ntchito ya glutaminergic mu amygdala, chigawo cha ubongo chogwirizana ndi kukumbukira.

Tianeptine imachepetsa yankho la hypothalamic-pituitary-adrenal kupsinjika, ndipo motero imaletsa nkhani zokhudzana ndi khalidwe lachisokonezo. Mu makoswe, kupanikizika kovuta kwambiri kumapangitsa kuchuluka kwa extracellular magutamate m'thupi la amygdala lomwe limaletsedwa ndi tianeptine. Chochititsa chidwi n'chakuti SSRI fluoxetine inakula kwambiri m'magulu amtundu wa glutamate m'thupi la amygdala mosasamala kanthu za mavuto. deta zimenezi zikusonyeza kuti limagwirira cha zochita za tianeptine ndi wosiyana SSRIs ndi kuthandiza amanena kuti limagwirira cha zochita za tianeptine chikukhudza zosinthidwa za ntchito glutaminergic mu amygdala ndi hippocampus.

Kuwonjezera zimagwirira pamwamba, tianeptine ndi antidepressant wapadera ndi mankhwala anxiolytic kumene kumapangitsa munthu kutengedwa wa serotonin (5-hydroxytryptamine; 5-HT), ndipo 5-hydroxyindoleacetic asidi (5-HIAA) mu ubongo minofu.

Ngakhale kuti minoaminergic neurotransmitters serotonin (5-HT), noradrenaline (NA) ndi dopamine (DA) zimatsimikiziridwa kuti zimagwirizana ndi kuchitika kwa matenda ovutika maganizo, tsopano akuzindikira kuti kuchepa kwa monoamine sikukwanira kufotokoza njira yogwiritsira ntchito mankhwala oponderezedwa mankhwala.

ubwino of Tianeptine sodium salt ufa (30123-17-2)

  • Tianeptine mchere wa sodium ukhoza kuchiza matenda aakulu ovutika maganizo.
  • Mchere wa Tianeptine wa sodium uli ndi makhalidwe odana ndi nkhawa komanso otetezeka komanso otchuka.
  • Mchere wa tianeptine umatonthoza mtima komanso umakhala wabwino.
  • Mchere wa Tianeptine wa sodium ukhoza kulepheretsa kuopsa kwa mantha.
  • Mankhwala a tianeptine sodium amachititsa ululu wopangidwa ndi fibromyalgia.
  • Mchere wa tianeptine wa sodium ogwiritsidwa ntchito pochiza kupsinjika kwa amuna omwe ali ndi erectile dysfunction.
  • Tianeptine sodium salt imakhala yothandiza kwambiri kwa ADHD.
  • Tianeptine mchere wa sodium imalimbikitsanso kuti thupi likhale lopanda mphamvu.

akulimbikitsidwa Tianeptine sodium salt ufa (30123-17-2) Mlingo

Sodium ya Tianeptine imakhala ndi theka la moyo pafupipafupi 2.5 hours14, ndipo imafuna kubwezeretsedwa kwa tsiku lonse. Mlingo wa tianeptine sodium ndi 12.5 mg watengedwa katatu tsiku ndi tsiku, okwanira 37.5mg pa tsiku.

Musapitirire 50mg ya Tianeptine Sodium tsiku limodzi. Kuchita zimenezi kungatsegule chitseko cha kuchitiridwa nkhanza komanso kusokoneza bongo.

Zotsatira zoyipa wa Tianeptine sodium salt powder (30123-17-2)

Tianeptine sodium salt ufa imagwirizana ndi mbali zambiri za ubongo kuphatikizapo opiod receptors, zomwe zingapangitse zotsatira zoyipa. Zotsatira zina zotsatirazi ndizo zotsatirazi:

Mutu (mpaka 18%)

Chizungulire (mpaka 10%)

Kugonjetsa / kutentha usiku (mpaka 20%)

Kugona (mpaka 10%)

Pakamwa pakamwa (mpaka 20%)

Zotsatira zina zimaphatikizapo zinthu monga kudzimbidwa, kunyoza, nkhawa kapena chiwindi. Zovuta kwambiri zimaphatikizapo kuchoka pambuyo pozunzidwa ndipo 0.1 - 0.3% ya ogwiritsa ntchito adzakhala ndi vuto ili. Momwe mungathe kuwonera, zotsatira za zotsatira za mankhwala a Tianeptine sodium zidzadalira payekha komanso biochemistry.

Ndikoyenera kudziwa kuti:

Odwala achikulire ayenera kutenga mlingo waung'ono wa tianeptine mchere wa sodium, monga momwe odwala ayenera kuchepa. Mlingo sayenera kusinthira odwala ndi uchidakwa kapena kwa chiwindi kuwonongeka, kapena odwala pa dialysis .While Antidepressants, ngati tianeptine, adakula chiopsezo kawopsedwe chiwindi.


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1 review kwa Mpweya wa Tianeptine wamchere wa sodium (30123-17-2)

  1. phcoker -

    Ali ndi mchere wambiri wa sodium wa sodium kuti ayesedwe, zotsatira zowonetsera zimasonyeza kwambiri khalidwe labwino ndi chiyero!

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