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Mafuta a Avanafil akuda (330784-47-9)

Avanafil ufa umagwiritsidwa ntchito pochiza amuna omwe ali ndi vuto loti azigonana (lotchedwanso kusabala kwa kugonana). Avanafil ndi a gulu la …… ..


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum
mphamvu: 1290kg / mwezi

Kufotokozera

Mawonekedwe a Avanafil akuda (330784-47-9) kanema

Mafuta Avanafil akuda (330784-47-9) Ndemanga

Raw Avanafil ufa ndi PDE5 inhibitor yovomerezeka chifukwa chokhala ndi vuto logontha (ED: kusabala mphamvu; kulephera kupeza kapena kusunga erection mwa amuna). Raw Avanafil ufa amachita mwa kuletsa mtundu wina wa phosphodiesterase 5 enzyme womwe umapezeka m'mizimba yambiri yamthupi, koma makamaka mu corpus cavernosum penis, komanso retina. Imagwira ndikuwonjezera kutuluka kwa magazi kwa mbolo nthawi yokondweretsa. Mankhwala ena ofanana ndi sildenafil, tadalafil ndi vardenafil. Ubwino wa Raw Avanafil ufa ndikuti uli ndi kuyamba mwachangu kwambiri poyerekeza ndi zoletsa zina za PDE5. Imatengeka mwachangu, mpaka kufika pazovuta pafupifupi pafupifupi mphindi za 30-45.Pakati magawo awiri mwa atatu a achinyamata adatha kuchita zachiwerewere mkati mwa mphindi za 15.

Mafuta Avanafil akuda (330784-47-9) Szizindikiro

Name mankhwala Mafuta Avanafil akuda
Mankhwala Name 330784-47-9;STENDRA; (s)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide; TA 1790; TA-1790
Brand NAme Stendra ndi Spedra
Kalasi ya Mankhwala PDE5 inhibitor
Nambala ya CAS 330784-47-9
InChIKey WEAJZXNPAWBCOA-INIZCTEOSA-N
Maselo Fmphutsi C23H26ClN7O3
Maselo Wasanu ndi atatu 483.95
Misa ya Monoisotopic 483.179 g / mol
Kusungunula Pmafuta 150-152 ° C
Fkubwezeretsanso Pmafuta Palibe deta yomwe ilipo
Halimo Half-Life Kuthetsa hafu ya moyo = 5.36 - maola 10.66
Maonekedwe White powder
Szovuta DMSO, Methanol
Smazunzo Tkutentha Sungani ku 4 ° C
ntchito Phosphodiesterase (PDE5) inhibitor, imagwiritsidwa ntchito pochotsa kusowa kwa magazi.

Mafuta Avanafil akuda (330784-47-9) Ndemanga

Avanafil imagwiritsidwa ntchito pochotsa kusowa kwa thupi (ED: kusabala; kusatha kupeza kapena kusunga lingaliro mwa amuna). Avanafil ufa ali mgulu lamankhwala otchedwa phosphodiesterase (PDE) inhibitors. Imagwira ndikuwonjezera kutuluka kwa magazi kwa mbolo nthawi yogonana. Kutuluka kwa magazi kumeneku kumatha kupangitsa kuti erection. Avanafil ufa samachiritsa kusokonezeka kapena kukulitsa chilakolako chogonana. Avanafil imalepheretsa kutenga pakati kapena kufalikira kwa matenda opatsirana pogonana monga kachilombo ka HIV.

Mafuta Avanafil (330784-47-9) Njira ya Ntchito

Avanafil ndi kusankha kwa phosphodiesterase 5 (PDE5) inhibitor yogwiritsidwa ntchito pochiza matenda osokoneza bongo omwe amayamba chifukwa cha matenda ashuga, zaka zomwe zimapangitsa kupsinjika kwa oxidative kapena zovuta zina. Avanafil ikuletsa cGMP enieni a phosphodiesterase mtundu wa 5 (PDE5) womwe umayambitsa kusokonezeka kwa cGMP mu corpvern cavernosum yomwe ili kuzungulira mbolo. Kulowa kwa penile pa kugonana kumapangitsa kuti magazi azituluka chifukwa cha kupumula kwa mitsempha ndi mafinya osalala. Kuyankha uku kumaphatikizidwa ndi kutulutsidwa kwa nitric oxide (NO) kuchokera kumalo osungira mitsempha ndi maselo a endothelial, omwe amachititsa kaphatikizidwe ka cGMP maselo osalala. Cyclic GMP imapangitsa kupumula kwa minofu ndikuwonjezereka kwa magazi kulowa mu corpus cavernosum. Kuletsa kwa phosphodiesterase mtundu 5 (PDE5) ndi avanafil kumawonjezera ntchito pakukulitsa kuchuluka kwa cGMP.

Ntchito ya Avanafil powder (330784-47-9)

Avanafil ufa umagwiritsidwa ntchito pochiza amuna omwe ali ndi vuto lotha kugona (lotchedwanso kusabala kwa kugonana).

Pulogalamu ya Avanafil yotchulidwa (330784-47-9) Mlingo

Kwa anthu ambiri, chiyambi choyamba cha avanafil powder ndi 100 mg tsiku lililonse kutengedwa maminiti a 30 musanayambe kugonana. Malinga ndi kuyenerera kwa kuyankha kapena zotsatira zake, mlingowo ukhoza kuwonjezeka kufika ku 200 mg kapena wapita ku 50 mg tsiku. Anthu omwe akumwa mankhwala omwe amawonjezera magazi a avanafil sayenera kupitirira mlingo wa 50 mg mu maola 24 (Onani kuyanjana kwa mankhwala).

Ubwino wa ufa wa Avanafil (330784-47-9)

Lekani kugwiritsa ntchito avanafil ndikuitana dokotala mwamsanga ngati muli:

▪ kusintha masomphenya;

▪ kumvetserani, kapena kutaya mwadzidzidzi kumva;

▪ kupweteka, kutupa, kutentha, kapena kufiira m'modzi kapena miyendo yonse;

▪ kupuma pang'ono, kutupa mmanja kapena mapazi;

▪ kumverera kosauka, monga momwe mungathere; kapena

▪ mbolo yomwe imapweteka kapena imatha maola a 4 kapena nthawi yayitali.

Zotsatira zowonjezereka zingaphatikizepo:

▪ kumutu;

▪ kutentha (kutentha, kufiira, kapena kumverera);

▪ zizindikiro zozizira monga mphuno kapena pakhosi, pakhosi; kapena

▪ ululu wammbuyo.

KULAMBIRA NDI KUSINTHA:

Nkhaniyi Ikagulitsidwa Kugwiritsa Ntchito Kafukufuku kokha. Migwirizano Yogulitsa. Osati Zongogwiritsa Ntchito Anthu, kapena Zamankhwala, Zoweta Zanyama, kapena Zogwiritsa Ntchito Panyumba.


Mafotokozedwe ndi zolemba zamagulu

Mafunso a 9 kuti mudzifunse musanatenge Avanafil

Zothandizira

  1. Ryan M Burke, Jeffery D Evans, Avanafil pochiza matenda osokoneza bongo: kuwunikira zomwe angathe kuchita, Vasc Health Risk Manag. 2012; 8: 517-523.
  2. DeRogatis LR, Burnett AL. Mliri wa matenda opatsirana pogonana. J Sex Med. 2008; 5: 289-300.
  3. Zhao C, Kim S, Yan D, et al. Kuchita bwino ndi chitetezo cha avanafil pakuchiza matenda osokoneza bongo: zotsatira za kuyesa kwamitundu yambiri, kusintha kwa khungu, khungu lodziwikiratu, kuyesedwa ndi placebo. BJU Int. 2012 Mar 27;

Shangke Chemical ndi makampani apamwamba kwambiri omwe amagwiritsa ntchito mankhwala omwe amathandiza kwambiri. Pofuna kuyendetsa khalidweli panthawi yopanga, akatswiri ambiri odziwa bwino ntchito, makina oyambirira kupanga zipangizo komanso ma laboratori ndi mfundo zofunika kwambiri.

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