Chithandizo cha Phosphatidylserine (51446-62-9)

March 9, 2020

Phosphatidylserine ndi aminophospholipid ndi amino acid yomwe imapangidwa mwachilengedwe mkati mwa …….

 


Chikhalidwe: Mu Kupanga Misa
Zokonzedwa ndi Zokonzedweratu Zopezeka
mphamvu: 1277kg / mwezi

 

Phosphatidylserine (51446-62-9) kanema

Phosphatidylserine Makulidwe

Name mankhwala Phosphatidylserine
Mankhwala Name Phosphatidyl-L-serine ; 1,2-Dioctadecanoyl-sn-glycero-3-phosphoserine ; Ptd-L-Ser ; PS ;
Name Brand N / A
Kalasi ya Mankhwala N / A
Chiyeretso 20% 、 50% 、 70%
Nambala ya CAS 51446-62-9
InChIKey TZCPCKNHXULUIY-RGULYWFUSA-N
Maselo Fmphutsi C42H82NO10P
Maselo Wasanu ndi atatu 792.1 g / mol
Misa ya Monoisotopic 791.567635 g / mol
Malo otentha  816.3 ± 75.0 ° C (Wonenedweratu)
Fkubwezeretsanso Pmafuta N / A
Halimo Half-Life N / A
mtundu ufa wachikasu
Szovuta  sungunuka ku Chloroform, Toluene; insonuble mu Ethanol,

Methanoli, Madzi

 

Smazunzo Tkutentha  gulani pa -20 ° C
Amalingaliro amagwiritsidwa ntchito pazakudya zowonjezera

mu zakumwa zinchito

mkaka wa mkaka wa makanda

 

Chidule cha Phosphatidylserine

Phosphatidylserine ndi aminophospholipid ndi amino acid yomwe imapangidwa mwachilengedwe mthupi. M'malo mwake, ndi phospholipid yomwe imapanga gawo lalikulu laubongo wamunthu. Tiyenera kudziwa, komabe, kuti ngakhale thupi limatha kupanga PS lokha, zambiri zimachokera mchakudya chathu. Tsoka ilo, zakudya zamakono masiku ano sizikhala ndi PS yokwanira. Pokhapokha mutakhala ndi thandizo lalikulu la Atlantic mackerel, mtima wa nkhuku, lecithin ya soya, ubongo wa ng'ombe, ndi hering'i ya Atlantic, mukufunika kuti mutenge PS yanu kuchokera ku chowonjezera. PS imagwiranso ntchito ngati chizindikiritso cha apoptosis, yomwe ndi njira yofananira yakufa kwa khungu komwe ndikofunikira kuti thupi likule ndikukula. Tithokoze mayesero azachipatala omwe adachitika ku Italy, mawu ofunikira pakukweza kukumbukira mwachangu afalikira padziko lonse lapansi, zomwe zidapangitsa kuti pakadali pano azifunafuna nootropic.

 

Kodi Phosphatidylserine?

Phosphatidylserine (Ptd-L-Ser kapena PS), ndi michere ya phospholipid yomwe imapezeka mu nsomba, masamba obiriwira obiriwira, soya ndi mpunga, ndipo ndizofunikira pakugwira ntchito kwawoko kwamankhwala am'mimba a neuronal ndikuyambitsa Protein kinase C (PKC) yomwe yawonetsedwa kukhala ndi gawo la kukumbukira. Mu apoptosis, phosphatidyl serine imasamutsidwa ku tsamba lakunja la membrane wa plasma. Ichi ndi gawo limodzi mwa njira yomwe khungu limayang'ana ku phagocytosis. PS yawonetsedwa kuti ikuyenda pang'onopang'ono mitundu ya nyama. PS yafufuzidwa pamiyeso yaying'ono ya malo osavomerezeka kawiri ndipo yawonetsedwa kuti ikuwonjezera magwiridwe antchito kukumbukira kwa okalamba. Chifukwa cha mapentail ozindikira bwino a phosphatidylserine, chinthucho chimagulitsidwa ngati chowonjezera cha zakudya kwa anthu omwe amakhulupirira kuti akhoza kupindula ndi kuchuluka kowonjezera.

Zakudya zowonjezera zidakonzedwa kuchokera ku magwero a bovine komabe matenda a Prion amawopsya mu 1990s adaletsa izi, ndipo njira yokhazikitsidwa ndi soya idalandiridwa.

Phosphatidylserine Powder, Organic Phosphatidylserine amapangidwa mu thupi la ma serine, Italy, Scandinavia ndi maiko ena aku Europe amagwiritsidwa ntchito kwambiri pophika mankhwala a phosphatidylserine kuchitira kuchepa kwa magazi chifukwa cha kukalamba komanso kukumbukira kwakalamba kwa okalamba.

Chifukwa cholophilicity yake, imatha kudutsa chotchinga ndi magazi ndikulowa muubongo mutakomoka, ndikuchita gawo la minofu yofewa yam'mimba ndikukweza magazi ku ubongo.

Phosphatidylserine amagwiritsidwa ntchito kwambiri pakukonzanso ntchito zamaganizidwe, makamaka okalamba.

 

Phosphatidylserine ubwino

Phosphatidylserine imapezeka mwachilengedwe mu zakudya zina ndipo imagulitsidwanso mu mawonekedwe owonjezera zakudya. Phosphatidylserine zowonjezera zimatulutsidwa ngati njira yachilengedwe yothandizira matenda osiyanasiyana, kuphatikiza:

Chenjerani ndi vuto la kuchepekera kwa vuto loopsa (ADHD)

matenda a Alzheimer

nkhawa

Kusokonezeka maganizo

angapo sclerosis

kupanikizika

Phosphatidylserine imathandizira kuthana ndi zida zowononga zaulere, anti-oxidation.

Phosphatidylserine ali ndi ntchito yoletsa komanso kuchiza matenda amtima komanso a mtima.

Kuphatikiza apo, phosphatidylserine zowonjezera zimapangidwa kuti zisunge kukumbukira, kulimbikitsa kugona bwino, kusintha malingaliro, ndikuthandizira kuchita masewera olimbitsa thupi.

Kodi Phosphatidylserine amagwira ntchito bwanji?

Phosphatidylserine ndi mankhwala ofunikira okhala ndi zinthu zambiri mthupi. Ndi gawo limodzi la maselo ndipo ndi chofunikira kwambiri pakukonza ma cell, makamaka mu ubongo.

 

Phosphatidylserine ufa amagwiritsa ntchito

Phosphatidylserine ufa amagwiritsira ntchito zowonjezera zakudya kuti ubongo ukhale wogwira ntchito, Pewani matenda a Alzheimer's komanso kukumbukira kukumbukira.

Phosphatidylserine ufa amagwiritsira ntchito zakumwa zogwiritsira ntchito kuti athetse kupanikizika kwa kuphunzira ndi kugwira ntchito, kulimbikitsa kuyambiranso kwa kutopa kwaubongo komanso kusinthasintha kwa malingaliro.

Phosphatidylserine ufa umagwiritsa ntchito mkaka wa mkaka wa ana, zopangira mkaka kuti zipangitse khungu la khungu, kukonza luntha; yang'anani chidwi ndikupewa ana omwe ali ndi adhd.

Phosphatidylserine amagwiritsidwa ntchito ngati gawo lachilengedwe la oyendetsa sebum kuti azitha kusintha zotsatira za maphunziro.

 

Reference:

  • Lumikizanani pakati pamatenda oyamba, kupsinjika ndi kukhumudwa. Jagmag T, Tirant M, Lotti T. J Biol Regul Homeost Agents. 2017 Oct-Dec; 31 (4): 1037-1041.
  • Kuperewera kwa Atp8a1 kumalumikizidwa ndi kuposedwa kwa phosphatidylserine mu hippocampus ndikuchedwa kuchepa kwa kuphunzira kwa hippocampus. Levano K, Punia V, Raghunath M, Debata PR, Curcio GM, Mogha A, Purkayastha S, McCloskey D, Fata J, Banerjee P. J Neurochem. 2012 Jan; 120 (2): 302-13. doi: 10.1111 / j.1471-4159.2011.07543.x. Epub 2011 Dec 2.
  • Zotsatira za soy lecithin phosphatidic acid ndi phosphatidylserine complex (PAS) pama endocrine ndi mayankho amisala pamavuto am'mutu. Hellhammer J, Fries E, Buss C, Engert V, Tuch A, Rutenberg D, Hellhammer D. Kupsinjika. 2004 Jun; 7 (2): 119-26.
  • Kuwunikira kwa michere ndi mankhwala m'makina oyang'anira a kuperewera kwa nzeru zachidziwitso.Kidd PM. Altern Med Rev. 1999 Jun; 4 (3): 144-61. Unikani.
  • Antiphospholipid, antinuclear, Epstein-Barr ndi ma cytomegalovirus antibodies, ndi zotumphukira zosakanikirana-2 zolandila odwala osaya mtima. Maes M, Bosmans E, Suy E, Vandervorst C, Dejonckheere C, Raus J. J Afact Disord. 1991 Feb; 21 (2): 133-40.
  • Kafukufuku wakhungu kawiri ndi phosphatidylserine (PS) mwa odwala a parkinsonia omwe ali ndi vuto la misala ya mtundu wa Alzheimer's (SDAT). Fünfgeld EW, Baggen M, Nedwidek P, Richstein B, Mistlberger G. Prog Clin Biol Res. 1989; 317: 1235-46.