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Lithium orotate (5266-20-6)

Lithium orotate ndi mchere womwe umakhala ndi lithiamu (chitsulo cha alkali) ndi orotic acid (wopanga mwachilengedwe m'thupi) …….


Chikhalidwe: Mu Kupanga Misa
Zokonzedwa ndi Zokonzedweratu Zopezeka
mphamvu: 1277kg / mwezi

Kufotokozera

Lithium orotate (5266-20-6) zofunika

Name mankhwala Lithium orotate
Mankhwala Name orotic acid lithiamu mchere monohydrate ; lithiamu; 2,4-dioxo-1H-pyrimidine-6-carboxylate; Lithiiorotasmonohydricum; UNII-L2N7Z24B30;
Nambala ya CAS 5266-20-6
InChIKey IZJGDPULXXNWJP-UHFFFAOYSA-M
MUZIKONDWERETSA [Li +]. C1 = C (NC (= O) NC1 = O) C (= O) [O-]
Molecular Formula C5H5LiN2O5
Kulemera kwa maselo 180.04
Misa ya Monoisotopic 162.025285 g / mol
Melting Point ≥300 ° C
Malo otentha N / A
mtundu woyera
ntchito ver-the-counter lithiamu orotate imalimbikitsidwa ngati chowonjezera chaumoyo chogwiritsidwa ntchito ngati gwero la lithiamu lotsika; itha kugwiritsidwa ntchito kwa mankhwala ochepetsa mphamvu ya lithiamu orotate pochiza matenda osokoneza bongo, migraines, ndi kuvutika maganizo komwe kumachitika chifukwa cha kupuma kwamatenda.

Kodi Lithium orotate ndi chiyani?

Lithium orotate ndi mchere womwe umakhala ndi lithiamu (chitsulo cha alkali) ndi orotic acid (wopanga mwachilengedwe m'thupi). Pazipangazi, ma lithiamu samamangiriridwa kumaso kwa orion ya orotate, mmalo motengera kabati kaboni kapenanso zinthu zina, komanso monga mchere wina, amasiyana ndi lingaliro kuti apange ma lithiamu aulere. Ambiri mwa mafuta omwe amapezeka ndi lithiamu orotate amaperekedwa mu njira zamankhwala othandizira kudya, omasulidwa ngati chithandizo chachilengedwe pamavuto osiyanasiyana amisala yamaganizidwe, ngakhale amafufuzidwa pang'ono chabe pakati pa 1973-1986 kuti athandize ena pazamankhwala, monga uchidakwa ndi matenda a Alzheimer's .

Monga njira ina yothandizira, lithiamu orotate imatha kusintha lithiamu ndikugwiritsidwa ntchito pochiza komanso kupewa ma episode a mania mwa anthu omwe ali ndi vuto la kupuma. Lithium akuti amathandizira komanso kupewa ma epicode a manic pochepetsa kuchepa kwa ubongo.

Ngakhale orotic acid nthawi zina amatchedwa vitamini B13, sikuti kwenikweni imakhala mavitamini. Mthupi la munthu, orotic acid imatha kupangidwa kuchokera ku tizilombo tating'onoting'ono topezeka m'matumbo. Kuphatikiza apo, ilinso ndi zina zambiri zogwiritsa ntchito mu ubongo ndi thupi.

Kodi Lithium orotate imagwira ntchito bwanji?

Mafuta a lithiamu a orotic acid (lithiamu orotate) amasintha zotsatira zenizeni za lifiyamu yambiri poonjezera kugwiritsidwa ntchito kwa lifiyamu. The orotates imayendetsa lifiyamu kupita kumtundu wa mitochondria, lysosomes ndi maselo a glia. Lithium orotate imakhazikitsa michere ya lysosomal ndikuletsa ma enzyme zochita zomwe zimayambitsa kutsika kwa sodium komanso kusowa kwamadzi mu zina za mchere wa lithiamu.

Mapindu a Lithium orotate

Lithium orotate amagwiritsidwa ntchito pochiza matenda owopsa kapena kuvutika mtima kwa odwala omwe ali ndi vuto la kupuma, komanso kupewa kutenganso kubwereza kwa ma epicode a manic. Itha kupindulitsanso iwo omwe ali ndi nkhawa kwambiri kuchokera ku PTSD ndipo angathandize ngati chikhazikitso cha mantha.

Pakati pa 80s kafukufuku wamowa adachitika ndipo adapeza kuti mankhwala a Lithium orotate tsiku lililonse amathandizira oledzera paulendo wawo kuti asiye kumwa. Omwe ali ndi vuto la OCD komanso matenda oonera amatha kupindula nawo. Kuphatikiza apo, Lithium orotate samangogwiritsa ntchito chithandizo chaupangiri, komanso amathandizanso kupirira pakukonzanso.

Komanso Lithium orotate imathandizanso poteteza ubongo. Lithium orotate amateteza ubongo poletsa kutayika kwa maselo aubongo ndikupanga maselo ena amtundu waubongo. Zawonetsa kusintha kwa matenda a Parkinson, matenda a Alzheimer's and dementia. Kafukufuku wazinyama amawonetsa lithiamu orotate akuwonetsa kuwongolera pamavuto azakhungu ndi mikwingwirima. Ikhozanso kukhala yopindulitsa ngati yoteteza mu kuwonongeka kwamitsempha yamagetsi chifukwa cha matenda a Lyme komanso itha kutetezedwa ku ubongo shrinkage.

Mlingo wa lithium orotate

Chifukwa cha kuphatikiza kwakukulu kwa lithiamu orotate, mankhwala othandizira ndi ocheperako kuposa mawonekedwe a lithiamu. Pali mapindu ambiri otenga lithiamu orotate pamiyeso yotsika.

Mlingo wamba uli pakati pa asanu ndi 20 mg. Amathanso kuupereka ngati mawonekedwe amadzimadzi, pafupifupi 250mcg. Pa kumwa mankhwalawa, si woopsa.

Panthawi yakukhumudwa kwambiri, mankhwala othandizira a lithiamu orotate ndi 150 mg / tsiku. Izi zikufanizidwa ndi 900-1800 mg wa mitundu yomwe mumalandira. Munthawi iyi ya lithiamu orotate, palibenso zoyipa za ma lithiamu zomwe zimachitika komanso osafunikira kuwunika miyezo ya seramu.

Kugwiritsa ntchito kwa Lithium orotate

Monga chowonjezera chakudya, Lithium orotate ingagwiritsidwe ntchito mu Mlingo wocheperako kuchitira zinthu monga kupsinjika kwa manic, uchidakwa, ADHD ndi ADD, kukhumudwa, kuchita zachiwawa, PTSD, Matenda a Alzheimer's komanso kusamalira kupsinjika konse.

Mankhwala ena, lithiamu orotate angagwiritsidwe ntchito pochiza komanso kupewa zinthu zotsatirazi:

nkhawa

Matenda a bipolar

Mutu wamutu

Kusokonezeka maganizo

Glaucoma

kusowa tulo

Migraine

Matenda a Parkinson

Matenda osokoneza bongo

Komanso, lithiamu orotate imagwiritsidwanso ntchito pokonzanso kukumbukira, kuthetsa ululu komanso kuchepetsa nkhawa.

Lithium orotate zotsatira zoyipa

Kuphatikiza pamapindu omwe ali pamwambapa, lithiamu orotate imayambitsanso mavuto ena mthupi, monga beow:

Ripoti la 2007 lofalitsidwa mu Journal of Medical Toxicology limachenjeza kuti lithiamu orotate ingakhale ndi zotsatira zoyipa, kugwiritsa ntchito lithiamu orotate kungayambitse mseru komanso kunjenjemera. Pamodzi ndi mseru komanso kusanza, zimayambitsanso mtima wamavuto ndi mitsempha. Palinso nkhawa yoti kugwiritsa ntchito lithiamu orotate kungachepetse ntchito ya impso.

Komanso, lithiamu orotate amatha kuyanjana ndi mankhwala ena. monga ACE inhibitors, anticonvulsants, antidepressants, calcium channel blockers, dextromethorphan, loop diuretics, meperidine, methyldopa, ndi monoamine oxidase inhibitors (MAOIs), etc.

Poganizira zoopsa zaumoyo zomwe zimakhudzana ndi poizoni wa thium, muyenera kuyezetsa magazi pafupipafupi kuti muwonetsetse kuti mankhwalawa a mankhwalawa sakupezeka mukamagwiritsa ntchito lithiamu orotate.

Tsamba:

  • ACOG Committee on Exercise Bulletins — Obstetrics. ACOG Practice Bulletin: Maupangiri aupangiri wama kachipatala a maopaleshoni-gynecologists okwana 92, Epulo 2008 (alowa m'malo mwa zipolopolo 87, Novembala 2007). Kugwiritsa ntchito mankhwala amisala pa nthawi ya pakati komanso mkaka wa m`mawere. Obstet Gynecol. 2008; 111: 1001-1020.18378767.
  • Balon R. Zoopsa zomwe zingakhale ndi "mankhwala othandizira" a lithiamu orotate. Ann Clin Psychiatry. 2013; 25 (1): 71.23376874.
  • Barkins R. Low-dose lithiamu ndi zotsatira zake zathanzi. Zotsatira za Nutr. 2016; 39 (3): 32-34.
  • Heim W, Oelschläger H, Kreuter J, Müller-Oerlinghausen B. kumasulidwa kwa lifiyamu kuchokera pakukonzekera kosasunthika. Faniziro la zilembo zisanu ndi ziwirizi. Mankhwala. 1994; 27 (1): 27-31.8159780.
  • Nieper, Hans Alfred (1973), "The matenda a lithiamu orotate. Phunziro la zaka ziwiri ”, Agressologie, 14 (6): 407-11, PMID 4607169.
  • Gong R, Wang P, Dworkin L. Zomwe tiyenera kudziwa pokhudzana ndi lifiyamu pa impso. Ndine J Physiol Renal Physiol. 2016; 311 (6): F1168-F1171.27122541.

KULAMBIRA NDI KUSINTHA:

Nkhaniyi Ikagulitsidwa Kugwiritsa Ntchito Kafukufuku kokha. Migwirizano Yogulitsa. Osati Zongogwiritsa Ntchito Anthu, kapena Zamankhwala, Zoweta Zanyama, kapena Zogwiritsa Ntchito Panyumba.


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Lithium orotate (5266-20-6) kanema

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Shangke Chemical ndi makampani apamwamba kwambiri omwe amagwiritsa ntchito mankhwala omwe amathandiza kwambiri. Pofuna kuyendetsa khalidweli panthawi yopanga, akatswiri ambiri odziwa bwino ntchito, makina oyambirira kupanga zipangizo komanso ma laboratori ndi mfundo zofunika kwambiri.

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