Lactoferrin (146897-68-9)

March 15, 2020
SKU: 62936-56-5
5.00 kuchokera 5 kutengera 1 kasitomala mlingo

Lactoferrin (LF), yemwe amadziwikanso kuti lactotransferrin (LTF), ndi glycoprotein woyimiriridwa m'madzi osiyanasiyana achinsinsi kuphatikizapo …….


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

Lactoferrin (146897-68-9) kanema

Lactoferrin ufa Szizindikiro

Name mankhwala Lactoferrin
Mankhwala Name lactotransferrin (EA
Brand NAme N / A
Kalasi ya Mankhwala N / A
Nambala ya CAS 146897-68-9
InChIKey N / A
Maselo Fmphutsi C141H224N46O29S3
Maselo Wasanu ndi atatu 87 kDa
Misa ya Monoisotopic N / A
Malo otentha N / A
Fkubwezeretsanso Pmafuta N / A
Halimo Half-Life N / A
mtundu pinki
Szovuta H2O: 1 mg / mL
Smazunzo Tkutentha 2-8 ° C
Amalingaliro N / A

Kodi Lactoferrin?

Lactoferrin (LF), yemwe amadziwikanso kuti lactotransferrin (LTF), ndi glycoprotein woyimiriridwa m'madzi osiyanasiyana achinsinsi kuphatikizapo mkaka. CRM iyi yokhala ndi mapuloteni oyenera ndi yoyenera ngati poyambira kugwiritsa ntchito ma calibrator kapena kuwongolera mitundu yosiyanasiyana ya kuyezetsa kwa LC-MS / MS kuphatikiza kuyesa kwa allergen, kuyezetsa makanda, zakudya kapena kupatsa thanzi komanso kuyesa kugwiritsa ntchito poyesa matenda

Colostrum, mkaka woyamba kupangidwa mwana wabadwa, umakhala ndi lactoferrin wokwanira kuchulukitsa kasanu ndi kawiri kuchuluka kwa mkaka womwe amapangidwa pambuyo pake. Lactoferrin imapezekanso m'madzi amaso, mphuno, thirakiti yopumira, matumbo, ndi kwina. Anthu amagwiritsa ntchito lactoferrin ngati mankhwala.

Lactoferrin amagwiritsidwa ntchito pochiza zilonda zam'mimba ndi zam'mimba, kutsegula m'mimba, ndi hepatitis C. Amagwiritsidwanso ntchito ngati antioxidant komanso kuteteza ku matenda a bacteria ndi ma virus. Ntchito zina zimaphatikizira kukulitsa chitetezo chathupi, kupewa kuwonongeka kwa minofu yokhudzana ndi ukalamba, kulimbikitsa mabakiteriya athanzi am'mimba, kupewa khansa, komanso kuwongolera momwe thupi limapangira chitsulo.

Ofufuza ena amati lactoferrin itha kutenga nawo gawo pakuthana ndi mavuto apadziko lonse monga kuchepa kwachitsulo ndi kutsegula m'mimba kwambiri.

Mu ulimi wama mafakitale, lactoferrin amagwiritsidwa ntchito kupha mabakiteriya pokonza nyama.

Lactoferrin ndi gawo limodzi la chitetezo chathupi ndipo amakhala ndi zochita zowononga chitetezo. Kuphatikiza pa ntchito zazikuluzikulu zophatikiza ndikunyamula chitsulo, Lactoferrin ilinso ndi ntchito komanso mawonekedwe a antibacterial iron, antivirus, kukana tiziromboti, kupha ziwalo, kupewa khansa ndikulimbana ndi khansa, ziwengo Anthu ena amatenga othandizira a lactoferrin kuti apindule ndi antioxidant komanso anti-kutupa.

Mapindu a Lactoferrin

Zotsatira Zotsutsana ndi Kutupa

Ngakhale limagwirira mwachindunji silinakhazikitsidwebe, lactoferrin ndi gawo lodziwika bwino la anti-kutupa mwa anthu.

Lactoferrin mu amniotic madzimadzi ndi gawo lofunikira kwambiri pakuchepetsa kutupa kwa amayi apakati kudzera pakuchepetsa milingo ya IL-6 ndikuchepetsa matenda omwe amachititsa kutupa.

Ili ndi zida zotsutsana ndi kutupa pamene ikuyanjana ndi chitetezo cha mthupi motsutsana ndi kachilombo ka Epstein-Barr, kuchepetsa kutupa mwa kulepheretsa kutseguka kwa TLR2 ndi TLR9 mu virus virus.

Katundu wa antibacterial

Lactoferrin amathandiza kuyimitsa ntchito ya mabakiteriya. Mabakiteriya ambiri amafunika chitsulo kuti azigwira ntchito, ndipo lactoferrin imaletsa mabakiteriya kutenga chitsulo mthupi la munthu.

Kuphatikiza pa izi, zimatha kulepheretsa kagayidwe kazakudya ka bakiteriya, kukhazikitsa makoma maselo awo, kapena kulumikizana ndi ma lysozymes mumkaka kuti aletse mabakiteriya.

Maudindo mu Fetal / Mwana wakhanda

Makanda amafunikira lactoferrin kuti apange ndikusinthana ndi matumbo athu. Imayang'anira kusiyanitsa maselo ang'onoang'ono am'mimba, kukhudza matumbo ochepa, kutalika, ndi kutulutsa mawu.

Mu fetus yaumunthu, lactoferrin amagwira ntchito ngati gawo lowongolera mafupa pamagawo oyamba a chitukuko cha mafupa a anthu.

Lactoferrin amalimbikitsa kukula kwa minyewa ya cartilaginous pamagawo osiyanasiyana a chitukuko cha fetal polimbikitsa ma osteocytes ndi ma osteoblasts.

Mu fetus yaumunthu, Lactoferrin amalimbikitsa kuyamwa kwachitsulo ndi kukhazikika kwa malire a burashi, kulola kukula kwathanzi komanso kukula kwa m'matumbo asanabadwe.

Mkulu wa Lactoferrin mu fetus amateteza kumatenda ndi zigawo za fetus kwinaku akuwonjezera ntchito.

Kodi Lactoferrin amagwira ntchito bwanji?

Lactoferrin amathandizira kuyendetsa kuyamwa kwa chitsulo m'matumbo ndi kutumiza kwachitsulo ku maselo.

Zikuwonekeranso kuti zimateteza ku kachilombo ka bakiteriya, mwina poletsa kukula kwa mabakiteriya powachotsera zofunikira kapena kupha mabakiteriya powononga makoma awo. Lactoferrin yomwe ili mkaka wa amayi imadziwika kuti imathandizira kuteteza makanda oyamwitsa ku matenda oyambitsidwa ndi bakiteriya.

Kuphatikiza pa matenda oyambitsidwa ndi bakiteriya, lactoferrin imawoneka kuti imagwira ntchito polimbana ndi matenda oyambitsidwa ndi ma virus ndi mafangasi.

Lactoferrin akuwonekeranso kuti akuphatikizidwa ndi kayendedwe ka mafupa (myelopoiesis), ndipo akuwoneka kuti amatha kukulitsa chitetezo cha mthupi.

Lactoferrin mavuto

Lactoferrin ufa ndi wotetezeka pazakudya zambiri. Kugwiritsa ntchito kuchuluka kwa mkaka wa lactoferrin mkaka wa ng'ombe kungakhale kotetezedwa mpaka chaka chimodzi. Lactoferrin yaumunthu yomwe imapangidwa kuchokera ku mpunga wokonzedwa mwapadera imawoneka yotetezeka mpaka masiku 14. Lactoferrin imatha kuyambitsa matenda otsegula m'mimba. Mlingo wambiri, zotupa pakhungu, kusowa kudya, kutopa, kuzizira komanso kudzimbidwa zanenedwapo.

Lactoferrin ufa ntchito ndi kugwiritsa ntchito

MILK YAKULENGA NDI LACTOFERRIN

Mu makanda obadwa onenepa kwambiri, mkaka wa ana olemeretsedwa ndi lactoferrin (wokhala ndi kapena popanda ma protein) umachepetsa chiopsezo cha kuchedwa kwa septicemia (bakiteriya kapena fungus).

Kuwona mozama zotsatira zake kunawonetsa kuti bovine lactoferrin adachepetsa matenda m'malo mopewa fungus kuti isafalikire. Izi zikusonyeza kuti lactoferrin imatha kuletsa matenda oyamba ndi mafangasi kuti asayambe matenda achilengedwe.

Bovine lactoferrin imatha kutchinga chotchinga cha magazi kudzera mu ma cell receptors, ndikuwongolera ma neuroprotection, neurodevelopment ndi kuphunzira kuthekera kwa zolengedwa.

Reference:

  • Barrington K et al, Mlandu wa Lacuna: woyeserera yekha wakhungu wazoyeserera wa lactoferrin wothandizira mwana wakhanda, J Perinatol. 2016 Aug; 36 (8): 666-9.
  • Lauterbach R et al., Lactoferrin - glycoprotein wa zofunikira zazikulu zochizira, Dev Period Med. 2016 Apr-Jun; 20 (2): 118-25.
  • Nbr1 yoyendetsedwa ndi Autophagy mu kusiyanasiyana kwa Lactoferrin-inachititsa osteoblastic. Zhang Y, Zhang ZN, Li N, Zhao LJ, Xue Y, Wu HJ, Hou JM. Biosci Biotechnol Biochem. 2020 Mar
  • Zotsatira za Bovine Lactoferrin Kulimbikira pa Iron Metabolism of Anemic Infants. Chen K, Zhang G, Chen H, Cao Y, Dong X, Li H, Liu C. J Nutr Sci Vitaminol (Tokyo). 2020
  • Lactoferrin: Wosewera Wotsutsa ku Neonatal Host Defense. Telang S et al. Zakudya zam'madzi. (2018)
  • Udindo wa Lactoferrin ku Neonates ndi makanda: Kusintha. Manzoni P et al. Ndine J Perinatol. (2018)
  • Enteral lactoferrin yowonjezera kupewa sepsis ndi necrotizing enterocolitis mu ana asanakwane. Pammi M et al. Cochrane Database Syst Rev. (2017)
  • Kodi Zowonjezera za Lactoferrin Zimapindulitsa Chiyani Kwa Akuluakulu Ndi Ana Aang'ono?