Beta-Lactoglobulin (9045-23-2)

March 11, 2020

β-Lactoglobulin ndiye puloteni wamkulu wamkaka wa ng'ombe ndi nkhosa (~ 3 g / l), ndipo umapezekanso m'mayamwidwe ena ambiri …….

 


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

 

Beta-Lactoglobulin (9045-23-2) kanema

Beta-Lactoglobulin (9045-23-2) Szizindikiro

Name mankhwala Beta-Lactoglobulin
Mankhwala Name β-Lactoglobulin (LG); BLG; β -Lg
Brand NAme N / A
Kalasi ya Mankhwala N / A
Nambala ya CAS 9045-23-2
InChIKey N / A
Maselo Fmphutsi N / A
Maselo Wasanu ndi atatu 18,300
Misa ya Monoisotopic N / A
Malo otentha  N / A
Fkubwezeretsanso Pmafuta N / A
Halimo Half-Life N / A
mtundu White powder
Szovuta  H2O: 10 mg / mL
Smazunzo Tkutentha  2-8 ° C
Amalingaliro β-Lactoglobulin A wa mkaka wa bovine wagwiritsidwa ntchito:
• ngati choyimira pakuwongolera chipangizo cha TriWave
• monga muyezo kuzindikiritsa ndi kusintha kwa to-lactoglobulin mu mkaka wa bovine mwa kusinthanso gawo lalikulu lamadzimadzi amadzimadzi (HPLC)
• pakuyeretsa komanso muyeso wa kulemera kwa maselo a proteinase
β-Lactoglobulin idagwiritsidwa ntchito pozindikira mitundu ya mitundu ya κ-kesiin mu mkaka ndi isoelectric yoyang'ana kwambiri electrophoresis.

 

Beta-Lactoglobulin (9045-23-2) Mwachidule

β-Lactoglobulin ndiye puloteni yayikulu yamkaka wa ng'ombe ndi nkhosa (~ 3 g / l), ndipo imapezekanso mumitundu ina yambiri yamamayi; chosiyana pokhala anthu. Pafupifupi 20% yamapuloteni amkaka amphongo ndi ma whey mapuloteni, chomwe chimakhala beta-lactoglobulin. β-Lactoglobulin nthawi zambiri imakhala chinthu chofunikira kwambiri pama Whey-based protein powders.

Mapuloteni amakoko amatha kukhala owopsa pakudya. Mkaka wa Bovine ndi imodzi mwazofunikira kwambiri pazakudya za allergenic, makamaka kwa ana. Zotsatira zake, kulembera kwa beta-lactoglobulin kapena mkaka ndizovomerezeka m'maiko ambiri. Ngakhale palibe malire azovomerezeka zamapuloteni a Whey, ndikofunikira kuti opanga zakudya azitha kuyesa zotsika kwambiri kuti ateteze anthu omwe samakonda komanso kupewa ziwonetsero za allergen.

Kodi Beta-Lactoglobulin ?

Beta-Lactoglobulin (ß-lactoglobulin, BLG) ndiye mapuloteni akuluakulu amkaka wowonekera ndipo amapezekanso mkaka wa nyama zina. Pafupifupi 20% ya mapuloteni amkaka a bovine ndi mapuloteni amadzi, ndipo gawo lake lalikulu ndi beta-lactoglobulin. Beta-Lactoglobulin nthawi zambiri amapanga kwambiri michere yama protein.

Beta-lactoglobulin ndi mapuloteni apadziko lonse a banja la lipocalin. Ili ndi maselo 18,300 ndipo imakhala ndi zotsalira za amino acid 162, kuphatikiza kuchuluka kwa ma amino acid (BCAAs).

Beta-lactoglobulin (b-lactoglobulin / BLG) ndi imodzi mwazofunikira kwambiri mkaka wa ng'ombe. Ndi imodzi mwamapuloteni omwe amadziwika kwambiri mumkaka kupangitsa kuti thupi lawo lisagwire, ngakhale kuti anthu ambiri amasiyana ndi mitundu yambiri ya mkaka. BLG ndiye mapuloteni ochulukirapo kwambiri mu Whey, chifukwa 50% ya mapuloteni athunthu mu kachigawo ka lactoserum ndi pafupifupi 10% ya mkaka wa ng'ombe.

Mokulira, ma globulin ndi mapuloteni ang'onoang'ono omwe amapinda bwino, ndipo ma lactoglobulin ndi ma globulins amapezeka mkaka. Ngati casein amatsuka mkaka (mwachitsanzo, ndi rennet kapena acidity), ma lactoglobulins amakhalabe kumbuyo kwa Whey (limodzi ndi lactalbumin, lactose, mchere, ndi ma immunoglobulins). Mapuloteni ndi pafupifupi 10% ya zothetsera zowuma za Whey, ndipo beta-lactoglobulin ndi pafupifupi 65% ya 10% imeneyo.

Alfa-lactoglobulin amatenga nawo lactose synthesis. Cholinga cha beta-lactoglobulin sichimveka bwino, ndipo ngakhale chimatha kumanga mamolekyulu ambiri a hydrophobic, cholinga chake chachikulu ndikungokhala ngati gwero la amino acid. Beta-lactoglobulin yawonetsedwanso kuti ikhoza kumangiriza chitsulo kudzera m'makola am'mimba ndipo mwanjira imeneyi imatha kukhala ndi gawo polimbana ndi tizilombo toyambitsa matenda.

Beta-Lactoglobulin amapindula

Podziwa kuti Whey protein ndi chisakanizo cha beta-lactoglobulin, alpha lactalbumin, bovine serum albumin, ndi ma immunoglobins. Anthu amakonda kugwiritsa ntchito ma Whey ngati othandizira, kuphatikiza zolimbitsa thupi, kuti athandizire kukulunga mapuloteni amtundu wa minofu ndikulimbikitsa kukula kwa minofu yowonda.

Phindu lomwe mungakhale nalo limaphatikizapo kuchepetsa kunenepa, katundu wa anti-cancer, Kuchepetsa cholesterol, mphumu, kuthamanga kwa magazi ndi matenda amtima, Kuchepetsa kuchepa kwa anthu omwe ali ndi HIV.

Mosiyana ndi proteni ina yayikulu yama Whey, α-lactalbumin, palibe ntchito yomveka yomwe yadziwika ndi lact-lactoglobulin, izi ngakhale zili gawo lalikulu kwambiri laling'ono lamapuloteni apadziko lonse omwe amakhala kutali ndi whey (β-lactoglobulin ≈⁠ ⁠65%, α-lactalbumin 25⁠ ⁠8%, seramu albumin 2⁠⁠XNUMX%, ina ≈⁠XNUMX%). β-lactoglobulin ndi lipocalin protein, ndipo imatha kulumikiza ma molekyulu ambiri a hydrophobic, kuwonetsa kuti ali ndi gawo ponyamula. β-lactoglobulin yawonetsedwanso kuti imatha kumanga chitsulo kudzera pa siderophores ndipo potero imatha kuthana ndi tizilombo toyambitsa matenda. Homologue wa β-lactoglobulin akusowa mkaka wa m'mawere wa anthu.

Beta-Lactoglobulin (BLG) ndiye mapuloteni ochulukitsitsa kwambiri mkaka wa bovine. LG yaphunziridwa kwambiri pamakampani azakudya chifukwa cha zopatsa thanzi komanso magwiridwe antchito pazinthu zosiyanasiyana zachilengedwe.

Kuphatikiza apo, BLG itha kukhala yotsika mtengo yotsutsana ndi antioxidant michere yomwe imapezeka mosavuta komanso yosavuta. BLG itha kukhala ngati michere ya antioxidant yomwe imapezeka mosavuta komanso yotsika mtengo m'moyo watsiku ndi tsiku. Ripoti lathu lakale lidawonetsa kuti cysteine ​​yaulere ya BLG imathandizira kuteteza mkaka mu antioxidant. BLG imayambitsa 50% ya antioxidant ya mkaka. Sikuti BLG imangokhala ngati michere ya antioxidant, imathanso kunyamula ma antioxidants ena kudzera m'thumba lake lomangirira. Chifukwa chake, zimawonjezera kupezeka kwa bioavailability komanso kuchuluka kwa ma antioxidants.

β-Lactoglobulin ndiye puloteni wamkulu wamkaka wa bovine owerengera pafupifupi 50% ya mapuloteni mu Whey koma samapezeka mkaka wa munthu. β-Lactoglobulin imayambitsa magwiridwe antchito komanso opatsa thanzi zomwe zapangitsa kuti mapuloteniwa akhale zinthu zambiri zogwiritsidwa ntchito pophatikiza zakudya zambiri komanso mitundu yambiri.

 

Beta-Lactoglobulin mavuto

Beta-lactoglobulin (b-lactoglobulin / BLG) ndi imodzi mwazofunikira kwambiri mkaka wa ng'ombe. Ndi imodzi mwamapuloteni omwe amadziwika kwambiri mumkaka kupangitsa kuti thupi lawo lisagwire, ngakhale kuti anthu ambiri amasiyana ndi mitundu yambiri ya mkaka. BLG ndiye mapuloteni ochulukirapo kwambiri mu Whey, chifukwa 50% ya mapuloteni athunthu mu kachigawo ka lactoserum ndi pafupifupi 10% ya mkaka wa ng'ombe.

Zizindikiro za kugunda kwa beta-lactoglobulin:

Zofiyira kapena ming'oma

Kuyabwa

nseru

Kutseka

Kusokonezeka kwa m'mimba

kutsekula

kutupa

kudzimbidwa

Anaphylaxis (chosowa)

 

Beta-Lactoglobulin ufa ntchito

β-Lactoglobulin ndiye puloteni wamkulu wamkaka wa bovine owerengera pafupifupi 50% ya mapuloteni mu Whey koma samapezeka mkaka wa munthu. β-Lactoglobulin imayambitsa magwiridwe antchito komanso opatsa thanzi zomwe zapangitsa kuti mapuloteniwa akhale zinthu zambiri zogwiritsidwa ntchito pophatikiza zakudya zambiri komanso mitundu yambiri.

 

Reference:

Ma β-Lactoglobulin omwe amachititsa kuti kutentha azikhala ngati onyamula mafuta achilengedwe a polyunsaturated. Perez AA, Andermatten RB, Rubiolo AC, Santiago LG Food Chem. 2014 Sep 1; 158 (): 66-72.

Kapangidwe ndi kuwunika kwa ziweto za bovine β-lactoglobulin yothandizidwa ndi radiation ya kuthandizidwa ndi sonication. Yang F, Zou L, Wu Y, Wu Z, Yang A, Chen H, Li X. J Mkaka Sci. 2020 Feb 26

Kusanthula kwa Genomic kwa Zigawo Zama protein a mkaka ku Brown Swiss Cattle. Macedo Mota LF, Pegolo S, Bisutti V, Bittante G, Cecchinato A. Nyama (Basel). 2020 Feb 2