Anandamide (AEA) (94421-68-8)

March 15, 2020
SKU: 77472-70-9
5.00 kuchokera 5 kutengera 1 kasitomala mlingo

Anandamide, yemwe amadziwikanso kuti N-arachidonoylethanolamine (AEA), ndi mafuta acid neurotransmitter ochokera ku …… ..


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum

Anandamide (AEA) (94421-68-8) kanema

Anandamide (AEA) (94421-68-8) Szizindikiro

Name mankhwala Anandamide (AEA)
Mankhwala Name Arachidonylethanolamide; N-Arachidonoylethanolamine; Anandamide (20.4, n-6);

N-Arachidonoyl-2-hydroxyethylamide; Arachidonoyl ethanolamide; AEA;

Nambala ya CAS 94421-68-8
InChIKey LGEQQWMQCRIYKG-DOFZRALJSA-N
MUZIKONDWERETSA CCCCCC = CCC = CCC = CCC = CCCCC (= O) NCCO
Molecular Formula C22H37NO2
Kulemera kwa maselo 347.53
Misa ya Monoisotopic 347.282429 g / mol
Melting Point N / A
Malo otentha 522.3 ± 50.0 ° C (Wonenedweratu)
kachulukidwe 0.92 g / mL pa 25 ° C (lit.)
mtundu kuwala kofiira
Stempage temp -20 ° C
Kutupa Mowa: sungunuka
ntchito Amagwiritsidwa ntchito kukumbukira, kusuntha, kuzindikira, kusuntha, kupweteka, kusangalatsa ndi chidwi.

Kodi Anandamide (AEA) ndi chiyani?

Anandamide, yemwe amadziwikanso kuti N-arachidonoylethanolamine (AEA), ndi mafuta acid neurotransmitter wotengedwa kuchokera ku non-oxidative metabolism ya eicosatetraenoic acid (arachidonic acid. Ili ndi kapangidwe kofanana ndi ka tetrahydrocannabinol, gawo logwira ntchito la cannabis. chosokonezedwa makamaka ndi enzyme yamafuta acid amide hydrolase (FAAH), yomwe imatembenuzaondamide kukhala ethanolamine ndi arachidonic acid, Pomaliza, Anandamide imapangidwa mu neuron ndi reaction ya reaction yomwe imachitika pakati pa arachidonic acid ndi ethanolamine motsogozedwa ndi calcium ion ndi cyclic monophosphate adenosidase. Ndiwotsogola kwa gulu la zinthu zomwe zimagwira ntchito zolimbitsa thupi (Prostamides) zomwe zimagwira ntchito zambiri zolimbitsa thupi, kuphatikizapo kulakalaka, kukumbukira, kupweteka, kupsinjika, komanso chonde.

Anandamide mumapezeka zinthu zambiri monga sea urchin roe, ubongo wa nkhumba ndi mbewa, ndi zina zambiri, koma kuchuluka kwake ndikochepa. Komanso, ofufuzawo adapezanso Anandamide ndi zinthu ziwiri (N-oleoylethanolamine ndi N-Linoleylethanolamine) mu chokoleti chamdima. Anandamide amapezekanso m'mbewu zina Zopakidwa, (mkate yoyera), Mowa (makamaka, kugwiritsa ntchito kwambiri kapena kumwa kwambiri), shuga woyengedwa, mafuta a Trans, Zakudya zomwe zimaphikidwa m'mafuta a masamba ndi Zakudya zopanda mankhwala omwe amakhala ndi mankhwala osokoneza bongo etc.

Monga gawo la endocannabinoid system (ECS), Anandamide imatchulidwa kuti amawongolera homeostasis limodzi ndi gulu lina la cannabis ngati 2-AG ndi endogenous can receptors thupi lonse. Dongosolo ili limapezeka M'magulu onse am'magazi. Anandamide amatenga mbali pakukhazikitsa njira zamadyetsedwe komanso chidwi cha neurogenic ndi chisangalalo, kusunga thupi lathu ndi malingaliro athu zonse. Kafukufuku wapeza kuti malingaliro athu, chisangalalo, mantha, nkhawa, komanso kuthekera kupilira kupsinjika zonse zimayendetsedwa ndi dongosolo la endocannabinoid, komanso matenda osiyanasiyana kuchokera ku schizophrenia mpaka kukhumudwa amaphatikizidwa ndi milingo yachilendo.

Anandamide, wofanana ndi THC, ndi wogwirizira pang'ono wa CB1R. Itha kuyambitsa kupititsa patsogolo kwa "machitidwe athunthu" a ubongo. Ndizofunikira kudziwa kuti izi zonse zomwe zimapangitsa Anandamide kuwoneka ngati ikulimbikitsidwa ndi kuponderezedwa kwa pharmacologic popewa kuchepa kwake kwa kagayidwe kachakudya. Kupezeka kwa Anandamide kungapangitse kuti pakhale banja latsopano la mankhwala othandizira.

Ubwino wa Anandamide (AEA)

Anandamide, yemwe amadziwikanso kuti "bliss molekyule", ndiwothandiza kupukusira, neurotransmitter ndi endocannabinoid, yomwe ili ndi mapindu ambiri azaumoyo ndi malingaliro:

Anandamide amachepetsa kupanga maselo a khansa mwachangu. Mu 1998, gulu la asayansi aku Italy lidazindikira kuti anandamide imatha kulimbikitsa neurogeneis ndikupanga maselo atsopano amitsempha, amachedwa kupanga mapangidwe / kuwonjezera phindu la maselo a khansa ya m'mawere.

Kutha kwa Anandamide kulimbikitsa neurogeneis (mapangidwe a ma neurons atsopano) kumathandizira pakuwongolera machitidwe odyetsa komanso kupanga chidwi ndi chisangalalo cha mbewa. Izi zimathandiza kuthetsa zizindikiro za kukhumudwa ndi nkhawa. Kafukufuku wopangidwa mu 2015 wa anthu ndi mbewa adapeza kuti kuchuluka kwa anandamide kumatha kulimbikitsa kusintha kwa malingaliro ndi kuchepetsa mantha.

Kuphatikiza apo, kuthekera kwa anandamide kumangiriza ku CB1 ndi CB2 receptors kudzakhudzanso kwambiri zochita zamagetsi, kuwonetsa zabwino pokhudzana ndi kukumbukira, kusuntha, kuzindikira, kusuntha, kuwongolera kupweteka, kusangalatsa kudya komanso chonde.

Momwe mungakulitsire anandamide(AEA) milingo mthupi la munthu?

Chifukwa anandamide ali ndi gawo ngati neurotransmitter, othandizira wa vasodilator ndi seramu metabolite yaumunthu, komanso maubwino azachipatala ndi zamaganizidwe, mungafune kuwonjezera kuchuluka kwa anandamide m'thupi lanu. Nazi njira zina zokulitsira kwakanthawi mthupi mwa munthu:

- Zolimbitsa ThupiIng

Kafukufukuyu adapeza kuti patatha mphindi 30 zokha kuthamanga, zomwe achiamide (AEA) za anthu ndi agalu adakula. Ngati mukufuna kupindula kwambiri, chitani masewera olimbitsa thupi nthawi zambiri.

-Kudya chokoleti chakuda

Chokoleti chakuda chimakhala ndi gawo lalitali kwambiri la theobromine mu chokoleti chathanzi, ndipo theobromine imathandizira kukulitsa kupanga kwaamamide mu ubongo ndipo imachedwetsa kuwonongeka kwake.

- Kudya truffle wakuda

Black truffle (bowa wakuda) mwachilengedwe imakhala ndi anandamide. Ngakhale bowa sangathe kugwiritsa ntchito anandamide mwanjira iliyonse, ofufuza akukhulupirira kuti amagwiritsidwa ntchito kukopa nyama kuti idye ndikubala zipatso zake.

- Kuyang'ana kwambiri

Kafukufuku akuwonetsa kuti munthu akakhala mu dera (lotchedwa "kuyenda" kapena "dera",) lakuchuluka kwambiri, kugwira ntchito, komanso kusungika kwambiri, sikuti mungakhale wopanga zambiri kapena kupanga ntchito zabwino mu ubongo wanu. kuchuluka kwa mankhwala, monga serotonin, dopamine, endorphin ndi anandamide.

Komanso, tiyi, coriander ndi udzu winawake zingathandizenso kukulitsa kupanga kwa anandamide.

Tsamba:

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