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Mafuta a Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

(1 kasitomala review)

Mafuta a Lorcaserin hydrochloride hemihydrate powder ndi .......


Chikhalidwe: Mu Kupanga Misa
Unit: 25kg / Drum
mphamvu: 1280kg / mwezi

Kufotokozera

Mafuta a Lorcaserin hydrochloride hemihydrate powder (856681-05-5) kanema

Mafuta a Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Malangizo

Name mankhwala Yaikulu Lorcaserin hydrochloride hemihydrate ufa
Mankhwala Name (R) -8-chloro-1-tetrahydro-2,3,4,5-methyl-1h-3-benzazepine hydrochloride hemihydrate (R) -8-chloro-2,3,4,5-methyl-1-benzazepine hydrochloride hemihydrate;
Brand NAme Belviq
Kalasi ya Mankhwala 5-HT2C receptor inhibitor
Nambala ya CAS 856681-05-5
InChIKey WRZCAWKMTLRWPR-VSODYHHCSA-N
Maselo Fmphutsi C22H32Cl4N2O
Maselo Wasanu ndi atatu 482.31
Misa ya Monoisotopic 480.1268745
Kusungunula Pmafuta Palibe deta yomwe ilipo
Fkubwezeretsanso Pmafuta Palibe deta yomwe ilipo
Halimo Half-Life Lorcaserin ali ndi moyo wa hafu ya plasma ya ~ maola 11
mtundu White powder
Kutupa Madzi Kutentha 0.0709 mg / mL
yosungirako Tkutentha Palibe deta yomwe ilipo
Amalingaliro Yaikulu Lorcaserin hydrochloride hemihydrate ufa ntchito monga anti-kunenepa kwambiri mankhwala. Amakhala ndi chilakolako chofuna kudya komanso serotonergic agonist.

Mafuta a Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Ndemanga

Lorcaserin hydrochloride hemihydrate powder ndi hydrate ndiyo mtundu wa hemihydrate wa lorcaserin hydrochloride. Amagwiritsidwa ntchito monga mankhwala odana ndi kunenepa kwambiri. Amakhala ndi chilakolako chofuna kudya komanso serotonergic agonist. Lili ndi lorcaserin hydrochloride.

Mafuta a Lorcaserin hydrochloride hemihydrate powder amagwiritsidwa ntchito pofuna kuchiza kunenepa kwambiri kamene amakhudzana ndi cholesterol, kuthamanga kwa magazi, kapena mtundu wa 2 shuga.

A FDA amavomereza ufa wochuluka wa Raw Lorcaserin hydrochloride hydrohydrate powder kwa anthu omwe ali ochepa kwambiri (omwe ali ndi mchere wa thupi, kapena BMI, a 30 kapena apamwamba) kapena omwe ali olemera kwambiri (ali ndi BMI ya 27 kapena pamwambapa) komanso ali ndi zolemera chimodzi- zokhudzana ndi umoyo monga mtundu wa 2 shuga, kuthamanga kwa magazi kapena cholesterol.

Mafinya a Lorcaserin hydrochloride amadzimadzi amapanga ntchito poletsa chilakolako - makamaka poyambitsa ubongo wa serotonin, wotsekemera wa ubongo umene umachititsa kuti munthu azikhala wosangalala komanso wokhutira. Serotonin imakhudzidwanso; Mankhwala ambiri odetsa nkhaŵa amagwira ntchito poletsa kubwezeretsa kachilombo ka serotonin ndikusunga ubongo m'madzi. Ochita kafukufuku pa Arena amati mankhwala awo akukonzekera kuti azifufuza okha serotonin receptors zomwe zimakhudza chilakolako.

Lorcaserin hydrochloride hemihydrate powder (856681-05-5) Njira yogwira ntchito

Lorcaserin amakhulupirira kuti amachepetsera zakudya komanso amachititsa kuti thupi likhale losangalala mwa kuyambitsa ziwalo za 5-HT2C pa zovuta zogwiritsira ntchito po-opiomelanocortin neurons yomwe ili mu hypothalamus. Njira yeniyeni ya zochita siidziwika.

Lorcaserin pa mlingo woyenera tsiku ndi tsiku amalumikizana ndi othandizira a 5-HT2C poyerekeza ndi zizindikiro za 5-HT2A ndi 5-HT2B (onani Table 5), zina 5-HT receptor subtypes, 5-HT receptor transporter, ndi 5-HT malo obwereza .

ntchito ya Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

  • Kulakalaka chakudya: Agent amene amagwiritsidwa ntchito kuchepetsa chilakolako.
  • serotonergic agonist: Wothandizira omwe ali ndi chiyanjano kwa serotonin receptors ndipo amatha kutsanzira zotsatira za serotonin mwa kulimbikitsa ntchito ya physiologic m'maselo olandira maselo. Magulu a agonoton a Serotonin amagwiritsidwa ntchito monga anti-depressants, nkhaŵa zowopsya, komanso pochiza matenda a migraine.

Analimbikitsa Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

Popeza kuti mfundo zogwiritsira ntchito Lorcaserin hydrochloride hemihydrate sizikupezeka, mfundo zotsatirazi ndizo:

Lorcaserin HCL ufa 846589-98-8 imabwera mu mawonekedwe apiritsi ndipo imatengedwa nthawi zambiri 1-2 pa tsiku, kapena popanda chakudya. Lorcaserin iyenera kugwiritsidwa ntchito limodzi ndi zakudya zochepa zowonjezera kalori komanso ndondomeko yochita masewera olimbitsa thupi.

Mlingo wovomerezeka wa lorcaserin ndi 10 mg omwe amalandiridwa kamodzi pa tsiku. Lorcaserin ikhoza kutengedwa popanda kudya chakudya. Lorcaserin iyenera kuthetsedwa kwa odwala omwe amalephera kukwaniritsa osachepera 5% kulemera kwa sabata pa sabata 12 chifukwa odwalawa sangakhale ndi vuto lolemera kwambiri ndi mankhwala opitilira.

ubwino Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

Lorcaserin hydrochloride hemihydrate powder ndi yosankha 5-HT2C receptor agonist yomwe imalingalira kuchepetsa kudya chakudya kudzera pakatikati POMC dongosolo. Lorcaserin HCL powder phindu:

  • Lorcaserin hydrochloride hemihydrate powder amagwiritsidwa ntchito limodzi ndi zakudya ndi masewera olimbitsa thupi kuti athetse kunenepa kwambiri.
  • Nthaŵi zina Lorcaserin hydrochloride mafuta m'thupi amapangidwa kuti athetse kunenepa kwambiri komwe kungakhale kokhudzana ndi shuga, cholesterol yapamwamba, kapena kuthamanga kwa magazi.
  • Lorcaserin hydrochloride hemihydrate powder sichidzachiza matenda aliwonse omwe ali ndi matenda (monga matenda a mtima, shuga, kuthamanga kwa magazi).

Zotsatira zoyipa ya Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

Lorcaserin hydrochloride hemihydrate powder amagwiritsidwa ntchito pochiza kasamalidwe kalemera kolemera kwa akuluakulu omwe ali ndi chiwerengero cha mthupi (XIUMX) cha 30 kapena chachikulu (owonjezera) monga kuwonjezera pa zakudya zochepa zomwe zimachepetsa zakudya. Amavomerezedwa kuti agwiritsidwe ntchito ndi anthu akuluakulu omwe ali ndi BMI ya 27 kapena oposa (olemera kwambiri) ndipo omwe ali ndi vuto limodzi lolemera, monga kuthamanga kwa magazi (hypertension), kapena cholesterol (dyslipidemia). Komabe, zingakhalenso ndi zotsatira zina. Monga pansipa:

Tzotsatira zake zofala:

  • -Mafupi,
  • -Dzinessess,
  • -Wotopa,
  • -Nkhani,
  • -Khala mkamwa,
  • -Constipation, ndi
  • -Hayglycemia (shuga wotsika magazi).

Zotsatira zina zochepa koma zovuta zomwe zimakhudzana ndi lorcaserin zikuphatikizapo:

  • -Sinthani mavuto a valve,
  • -Makondwerero akumbukira kapena kukumbukira,
  • -Mabvuto a m'mtima,
  • -Kusokonezeka kapena maganizo a kudzipha,
  • -Kusintha kwabwino,
  • -Kukonda mtima pang'ono,
  • -Kuthyoka muwerengero wa magazi, ndi
  • -Zowonjezera mahomoni, prolactin.


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1 review kwa Mafuta a Lorcaserin hydrochloride hemihydrate powder (856681-05-5)

  1. phcoker -

    Wakulira Lorcaserin hydrochloride hemihydrate powder kuti ayese, kuyesa zotsatira kumasonyeza kwambiri khalidwe labwino ndi chiyero!

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