Kufotokozera
Mawindo obiridwa a Orlistat (96829-58-2) kanema
Mafuta a orlistat (96829-58-2)
Mafuta owopsa a Orlistat ali m'kalasi la mankhwala omwe amatchedwa lipase inhibitors omwe amagwira ntchito poletsa kutaya kwa 25% mwa mafuta omwe amadya ndipo amagwiritsidwa ntchito kulemera kwa anthu olemera kwambiri, zaka 18 ndi zakale, pamene amagwiritsidwa ntchito pamodzi ndi kuchepetsa-kalori ndi zakudya zonenepa. Mafuta akuluakulu a orlistat ndi mankhwala omwe amachititsa kuti munthu azidya kwambiri. Ntchito yake yaikulu ndikuteteza kutentha kwa mafuta kuchokera ku zakudya zaumunthu, motero kuchepetsa kudya kwa caloric. Mafuta akuluakulu a Orlistat amagwira ntchito poletsa kutentha kwa pancreatic lipase, yomwe imayambitsa triglycerides m'matumbo. Popanda mavitaminiwa, triglycerides kuchokera ku zakudya amaletsedwa kuti asadetsedwe m'malo mwa mafuta omwe amawathandiza kuti azikhala opanda mafuta. Mafuta Odzola Odzola Amagwiritsa ntchito anthu olemera kwambiri omwe angakhale ndi kuthamanga kwa magazi, shuga, cholesterol, kapena matenda a mtima. Mphamvu ya ufa wokhala ndi Raw Orlistat popititsa patsogolo kulemera kwake ndi yeniyeni koma yodzichepetsa. Zosungidwa zomwe zimachokera ku mayesero a zachipatala zimasonyeza kuti anthu amapatsidwa ufa Wowonjezera Wowonjezera, kuphatikizapo zakudya zakusintha, monga zakudya ndi masewero olimbitsa thupi, kutaya 2-3 kilogalamu (4.4-6.6 lb) kuposa omwe samamwa mankhwala pa chaka chimodzi. Mafuta oopsa a orlistat amadzichepetsa komanso amachepetsa kuthamanga kwa magazi ndipo amawoneka kuti amaletsa mtundu wa shuga wa 2, kaya ukhale wolemera kwambiri kapena zotsatira zina. Amachepetsa chiwerengero cha matenda a shuga a mtundu wachiwiri mwa anthu omwe ali ochepa kwambiri kuposa momwe moyo umasinthira.
Mafuta a orlistat (96829-58-2) Mafotokozedwe
| Name mankhwala | Mafuta aakulu a Orlistat |
| Mankhwala Name | Tetrahydrolipstatin, 1-((3-hexyl-4-oxo-2-oxetanyl)methyl)dodecyl-2-formamido-4-methylvalerate |
| Brand NAme | Alli, Xenical |
| Kalasi ya Mankhwala | lipase inhibitors |
| Nambala ya CAS | 96829-58-2 |
| InChIKey | AHLBNYSZXLDEJQ-FWEHEUNISA-N |
| Maselo Fmphutsi | C29H53NO5 |
| Maselo Wasanu ndi atatu | 495.745 g / mol |
| Misa ya Monoisotopic | 495.392 g / mol |
| Kusungunula Pmafuta | <50 ° C |
| Fkubwezeretsanso Pmafuta | Palibe tsiku likupezeka |
| Halimo Half-Life | Malingana ndi deta yochepa, theka la moyo wa ufa wofiira wa Raw Orlistat uli m'kati mwa ma 1 mpaka maola 2. |
| mtundu | White powder |
| Kutupa | DMSO: 19 mg / mL |
| yosungirako Tkutentha | nyengo yosungirako. 2-8 ° C |
| Amalingaliro | Gwiritsani ntchito kuchiza kunenepa kwambiri. |
Zam'mwamba Orlistat ufa (96829-58-2) Kufotokozera
Mafuta owopsa a Orlistat ali m'kalasi la mankhwala omwe amatchedwa lipase inhibitors omwe amagwira ntchito poletsa kutaya kwa 25% mwa mafuta omwe amadya ndipo amagwiritsidwa ntchito kulemera kwa anthu olemera kwambiri, zaka 18 ndi zakale, pamene amagwiritsidwa ntchito pamodzi ndi kuchepetsa-kalori ndi zakudya zonenepa.
Mafuta aakulu a Orlistat ndi mankhwala omwe amachititsa kuti munthu azidya kwambiri. Ntchito yake yaikulu ndikuteteza kutentha kwa mafuta kuchokera ku zakudya zaumunthu, motero kuchepetsa kudya kwa caloric. Mafuta akuluakulu a Orlistat amagwira ntchito poletsa kutentha kwa pancreatic lipase, yomwe imayambitsa triglycerides m'matumbo. Popanda mavitaminiwa, triglycerides kuchokera ku zakudya amaletsedwa kuti asadetsedwe m'malo mwa mafuta omwe amawathandiza kuti azikhala opanda mafuta. Mafuta Odzola Odzola Amagwiritsidwa ntchito pa anthu olemera kwambiri omwe angakhalenso ndi kuthamanga kwa magazi, shuga, cholesterol, kapena matenda a mtima. Mphamvu ya ufa wokhala ndi Raw Orlistat popititsa patsogolo kulemera kwake ndi yeniyeni koma yodzichepetsa. Zosungidwa zomwe zimachokera ku mayesero a zachipatala zimasonyeza kuti anthu amapatsidwa ufa Wowonjezera Wowonjezera, kuphatikizapo zakudya zakusintha, monga zakudya ndi masewero olimbitsa thupi, kutaya 2-3 kilogalamu (4.4-6.6 lb) kuposa omwe samamwa mankhwala pa chaka chimodzi. Mafuta oopsa a orlistat amadzichepetsa komanso amachepetsa kuthamanga kwa magazi ndipo amawoneka kuti amaletsa mtundu wa shuga wa 2, kaya ukhale wolemera kwambiri kapena zotsatira zina. Amachepetsa chiwerengero cha matenda a shuga a mtundu wachiwiri mwa anthu omwe ali ochepa kwambiri kuposa momwe moyo umasinthira.
Orlistat ufa (96829-58-2) Njira yogwira ntchito
Mafuta a orlistat ndi mtundu wa lipase kulepheretsa kulemera kwa mankhwala ndipo ndizochokera kumalo osungunuka. Orlistat imathandiza kuti mimba lipase ndi pancreatic lipase zisamayende bwino, ngakhale kuti sizimakhudza mavitamini ena am'mimba (monga amylase, trypsin ndi chymotrypsin) komanso phospholipase, komanso samakhudza kapangidwe ka mapuloteni, mapuloteni ndi phospholipids. Mankhwalawa sali okhudzidwa ngakhale ali ndi tsamba la m'mimba ndipo ali ndi vuto loletsa kusokoneza lipase. Orlistat amachititsa kuti michere yambiri ikhale yogwirizana ndi malo otentha a serine pa malo ogwira ntchito m'mimba ndi pancreatic lipase. Izi zimalepheretsa mafuta kudya kuti asatengere mafuta komanso ma diacylglycerol, motero sungathe kutengeka, kuchepetsa zakudya zamtundu wa caloric ndikuthetsa kulemera kwa thupi. Mankhwalawa safunikira kuti thupi lonse lizigwira ntchito. Zolemba za Orlistat ndizomwe zimadalira: mankhwala oyenera a Orlistat (120mg / d, tid, ndi zakudya), kuphatikizapo chakudya chochepa, akhoza kuchepetsa kulemera kwa 30% ya kuyamwa mafuta. Pa kafukufuku woyerekeza ndi odzipereka odziwika bwino komanso owonjezera, Orlistat sanali kwenikweni kutengeka ndi thupi konse ndipo anali ndi maganizo ochepa kwambiri a magazi. Pambuyo pa mlingo umodzi wamphongo (wamkulu kwambiri wa 800mg), magazi a Orlistat m'maola otsatirawa a 8 anali <5 ng / ml. Kawirikawiri, mlingo wa mankhwala a Orlistat umangotengedwa ndi thupi ndipo sungapezeko nthawi yayitali. Muyeso la mavitamini, mavoti a Orlistat ndi mapuloteni ena a seramu anapitirira 99% (mapuloteni omwe anali nawo makamaka anali lipoproteins ndi albumin), ndipo mlingo wake womangidwa ndi maselo ofiira ndi ofooka kwambiri.
Ubwino wa ufa wa Orlistat (96829-58-2)
▪ Orlistat amachepetsa thupi ndi zambiri kuposa 20% chifukwa cha mafuta
▪ Orlista imakuthandizani kuphunzira kuwerengera ndalama
▪ Orlista imakupatsani umoyo wabwino
▪ Orlista ili ndi zotsatira zabwino zomwe zimapatsa ogwiritsa ntchito chidaliro komanso chisangalalo
▪ Orlista imapereka zotsatira zosatha
▪ Orlista amachepetsa kuopsa kwa matenda monga hypotension, shuga, atherosclerosis komanso
cholesterol.
Analimbikitsa Orlistat ufa (96829-58-2) Mlingo
Mlingo woyenera wa ufa wa Orlistat ndi kapu imodzi ya 120-mg katatu patsiku ndi mafuta aliwonse omwe ali ndi mafuta (nthawi kapena pakutha pa ola la 1 pambuyo pa chakudya). Mankhwala pamwamba pa 120 mg katatu patsiku sanawonetsere kuti amapereka phindu lina.
Anthu ayenera kudya zakudya zopatsa thanzi, zochepa zomwe zimakhala ndi pafupifupi 30% ya mafuta kuchokera ku mafuta. Kudyetsa mafuta tsiku ndi tsiku, mafuta, mavitamini, ndi mapuloteni ayenera kugawidwa pazipangizo zitatu. Ngati chakudya nthawi zina chimasowa kapena mulibe mafuta, mlingo wa ufa wa Orlistat ukhoza kutayidwa.
Chifukwa chakuti ufa wa Orlistat wasonyeza kuchepetsa kuyamwa kwa mavitamini ena osungunula mafuta ndi betacarotene, anthu ayenera kulangizidwa kutenga multivitamin okhala ndi mavitamini osungunuka mafuta kuti athetse chakudya chokwanira. Kupatulapo, mavitamini othandizira ayenera kutengedwa maola ochepa a 2 asanayambe kapena pambuyo pa kayendedwe ka ufa wa Orlistat, monga nthawi yogona.
Zotsatira za ufa wa Orlistat (96829-58-2)
Ndi zachilendo kuona zotsatira za ufa wa Orlistat mutagwiritsa ntchito. Mukhoza kukhala ndi zotsatira zina kapena osati monga mutatha kumwa mankhwala ena onse. Zotsatira zambiri zomwe zimadza ndi kugwiritsa ntchito ufa wa Orlistat zimagwirizana ndi momwe zimagwirira ntchito m'thupi lanu. Nthawi zambiri zimakhala zofewa ndipo zimachitika nthawi zonse mutayamba mankhwala. Zimakhalanso zomwe mutatha mutatenga chakudya chambiri. Mwamwayi, ambiri amachoka pamene mankhwala akupitirira ndikutsatira chakudya choyenera.
Zotsatirazi ndizo zotsatira zofala:
▲ mutu
▲ Kumva ululu / kusokonezeka
▲ Kutaya kwa mafuta
▲ Mafuta odyera
▲ Khungu lachikopa
▲ Ululu wammbuyo
Kupatulapo, ngati mutadutsa zowawa zilizonsezi, muyenera kuchitapo kanthu mwamsanga ndikuitana dokotala mwamsanga. Ali;
▲ Kupweteka kwakukulu kwa m'mimba kumene sikuchoka.
▲ Njuchi kapena kuyabwa kwambiri
▲ Zovuta kumeza
▲ Kuvuta kupuma
|
KULAMBIRA NDI KUSINTHA: Nkhaniyi Ikagulitsidwa Kugwiritsa Ntchito Kafukufuku kokha. Migwirizano Yogulitsa. Osati Zongogwiritsa Ntchito Anthu, kapena Zamankhwala, Zoweta Zanyama, kapena Zogwiritsa Ntchito Panyumba. |
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